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anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) Antibodies

TNFRSF18 encodes a member of the TNF-receptor superfamily. Additionally we are shipping TNFRSF18 Proteins (24) and TNFRSF18 Kits (18) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNFRSF18 21936 O35714
TNFRSF18 8784 Q9Y5U5
TNFRSF18 500598  
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Top anti-TNFRSF18 Antibodies at antibodies-online.com

Showing 10 out of 312 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-TNFRSF18 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rat PE FACS   100 Tests Log in to see 6 to 8 Days
$390.50
Details
Mouse Rat Un-conjugated FACS   25 μg Log in to see 6 to 8 Days
$176.00
Details
Human Mouse Fluorescein FACS Detection of GITR/TNFRSF18 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) treated with 1 ug/mL PHA for 24 hours were stained with Mouse Anti-Human GITR/TNFRSF18 Fluorescein-conjugated Monoclonal Antibody. 25 Tests Log in to see 6 to 7 Days
$210.00
Details
Human Mouse PE FACS Detection of GITR/TNFRSF18 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) treated with 1 ug/mL PHA for 24 hours were stained with Mouse Anti-Human GITR/TNFRSF18 PE-conjugated Mono-clonal Antibody. 25 Tests Log in to see 6 to 7 Days
$249.38
Details
Human Mouse Allophycocyanin FACS Detection of GITR/TNFRSF18 in Human Blood CD4+ Lymphocytes by Flow Cytometry. Human peripheral blood CD4+ lymphocytes treated with PHA for 5 days were stained with Mouse Anti-Human GITR/TNFRSF18 APC-conjugated Monoclonal Antibody. 25 Tests Log in to see 6 to 7 Days
$262.50
Details
Mouse Rat Fluorescein FACS Detection of GITR/TNFRSF18 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$315.00
Details
Mouse Rat PE FACS Detection of GITR/TNFRSF18 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$393.75
Details
Mouse Rat Un-conjugated FACS, ELISA, WB FACS: GITR-transfected HEK 293 cells were stained significantly using anti-GITR (mouse), pAb . 100 μg Log in to see 5 to 8 Days
$299.25
Details

TNFRSF18 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TNFRSF18 Antibodies

  1. Human Monoclonal TNFRSF18 Primary Antibody for FACS - ABIN4896950 : Godfrey, Spoden, Ge, Baker, Liu, Levine, June, Blazar, Porter: Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. in Blood 2005 (PubMed)
    Show all 7 references for ABIN4896950

  2. Human Monoclonal TNFRSF18 Primary Antibody for FACS - ABIN4896942 : Tuyaerts, Van Meirvenne, Bonehill, Heirman, Corthals, Waldmann, Breckpot, Thielemans, Aerts: Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells. in Journal of leukocyte biology 2007 (PubMed)
    Show all 3 references for ABIN4896942

  3. Human Monoclonal TNFRSF18 Primary Antibody for FACS - ABIN4896944 : Mandapathil, Hilldorfer, Szczepanski, Czystowska, Szajnik, Ren, Lang, Jackson, Gorelik, Whiteside: Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells. in The Journal of biological chemistry 2010 (PubMed)
    Show all 3 references for ABIN4896944

  4. Mouse (Murine) Monoclonal TNFRSF18 Primary Antibody for FACS - ABIN4895259 : Cobb, Hertweck, Smith, OConnor, Graf, Cook, Smale, Sakaguchi, Livesey, Fisher, Merkenschlager: A role for Dicer in immune regulation. in The Journal of experimental medicine 2006 (PubMed)
    Show all 2 references for ABIN4895259

  5. Mouse (Murine) Monoclonal TNFRSF18 Primary Antibody for FACS - ABIN4895260 : Fecci, Sweeney, Grossi, Nair, Learn, Mitchell, Cui, Cummings, Bigner, Gilboa, Sampson: Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells. in Clinical cancer research : an official journal of the American Association for Cancer Research 2006 (PubMed)

  6. Mouse (Murine) Polyclonal TNFRSF18 Primary Antibody for FACS, ELISA - ABIN1169032 : Yu, Kim, Song, Min, Jeong, Youn: Identification of a ligand for glucocorticoid-induced tumor necrosis factor receptor constitutively expressed in dendritic cells. in Biochemical and biophysical research communications 2003 (PubMed)

  7. Human Polyclonal TNFRSF18 Primary Antibody for IHC, WB - ABIN2792138 : Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ... in Genome research 2003 (PubMed)

  8. Human Polyclonal TNFRSF18 Primary Antibody for WB - ABIN2792139 : Liu, Li, Mahesh, Pantanelli, Hwang, Siu, Nussenblatt: Glucocorticoid-induced tumor necrosis factor receptor negatively regulates activation of human primary natural killer (NK) cells by blocking proliferative signals and increasing NK cell apoptosis. in The Journal of biological chemistry 2008 (PubMed)

  9. Mouse (Murine) Monoclonal TNFRSF18 Primary Antibody for FACS - ABIN120234 : Cobbold, Castejon, Adams, Zelenika, Graca, Humm, Waldmann: Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)

More Antibodies against TNFRSF18 Interaction Partners

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) interaction partners

  1. GITR appears as a potential target for intervention during infection by the parasite Toxoplasma gondii, even though further studies are still necessary to better characterize the immune response triggered by GITR activation during T. gondii infection

  2. our data suggest a critical role for GITR in Treg cell homeostasis and indicate that Ptpn22 (show PTPN22 Antibodies) independently affects the differentiation status of Treg cells and their homeostatic behavior

  3. These findings provide further support for the continued development of agonist anti-GITR antibodies as an immunotherapeutic strategy for osteosarcoma. We suggest that our proposed immunotherapy could be developed further to improve osteosarcoma treatment

  4. Th9 cells and iTregs are developmentally linked and GITR can subvert tolerogenic conditions to boost Th9 immunity.

  5. GITR is a crucial player in differentiation of thymic regulatory T cells and expansion of regulatory T cells, including both thymic regulatory T cells and peripheral regulatory T cells.

  6. enhanced GITR-triggering mediates its protective, anti-viral effect on the CD8 (show CD8A Antibodies) T cell compartment by boosting CD4 (show CD4 Antibodies) T cell help.

  7. A CD4 (show CD4 Antibodies) T cell-intrinsic role for GITR in sustaining early CD8 (show CD8A Antibodies) and late humoral responses to collectively promote control of chronic LCMV clone 13 infection.

  8. GITRL (show TNFSF18 Antibodies) expressed on macrophages drives cytokine release and T cell activation, resulting in neuropathic pain via GITR-dependent actions. The GITRL (show TNFSF18 Antibodies)-GITR pathway might represent a novel target for the treatment of neuropathic pain.

  9. Data show that GITR agonist antibody alters Treg lineage stability inducing an inflammatory effector T cell phenotype. The resultant loss of lineage stability causes Treg to lose their intra-tumor immune suppressive function.

  10. Gene expression in the Gitr locus is regulated by NF-kappaB (show NFKB1 Antibodies) and Foxp3 (show FOXP3 Antibodies) through an enhancer.

Human Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) interaction partners

  1. Aberrant expression of GITR may contribute to systemic lupus erithematosus pathogenesis. Glucocorticoid may achieve its therapeutic effect partly by inducing GITR expression on Tresps rather than Tregs, which initiates the apoptosis of Tresp cells in SLE patients.

  2. GITR expression can enhance the sensitivity to Bortezomib by inhibiting Bortezomib-induced NF-kappaB (show NFKB1 Antibodies) activation.

  3. GITR is a crucial player in differentiation of thymic regulatory T cells and expansion of regulatory T cells, including both thymic regulatory T cells and peripheral regulatory T cells.

  4. Data may suggest a key role of regulatory GITR+CD25 (show IL2RA Antibodies) low/-CD4 (show CD4 Antibodies)+ T cells subset in the modulation of the abnormal immune response in lupus erythematosus (SLE) patients.

  5. results suggest that the GITR rs3753348 polymorphism may be involved in the development and susceptibility of CWP.

  6. these results show a higher susceptibility to apoptosis in patients' versus controls' T(reg (show EXTL3 Antibodies)) cells, suggesting that GITR is a T(reg (show EXTL3 Antibodies))-cell marker that would be primarily involved in T(reg (show EXTL3 Antibodies))-cell survival rather than in their suppressor function.

  7. Our findings indicate the possible involvement of GITR-GITRL (show TNFSF18 Antibodies) pathway in the pathogenesis of pSS (show CDSN Antibodies).

  8. GITR acts as a potential tumor suppressor in MM.

  9. Data indicate that the mRNAs of CTLA-4 (show CTLA4 Antibodies) and GITR genes were expressed at lower levels in CVID (show TNFRSF13B Antibodies) patients compared to control group.

  10. GITR is pathologically expressed on Treg cells in systemic lupus erythematosus.

TNFRSF18 Antigen Profile

Protein Summary

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene names and symbols associated with TNFRSF18

  • tumor necrosis factor receptor superfamily, member 18 (TNFRSF18) antibody
  • tumor necrosis factor receptor superfamily, member 18 (Tnfrsf18) antibody
  • AITR antibody
  • CD357 antibody
  • Gitr antibody
  • GITR-D antibody
  • TNFRSF18 antibody

Protein level used designations for TNFRSF18

tumor necrosis factor receptor superfamily member 18 , glucocorticoid-induced TNFR-related , tumor necrosis factor receptor superfamily, member 18 , glucocorticoid-induced TNFR-related protein , TNF receptor superfamily activation-inducible protein , activation-inducible TNFR family receptor

GENE ID SPECIES
419424 Gallus gallus
516256 Bos taurus
606971 Canis lupus familiaris
699559 Macaca mulatta
741567 Pan troglodytes
21936 Mus musculus
8784 Homo sapiens
500598 Rattus norvegicus
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