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Tumor Protein, Translationally-Controlled 1 Proteins (TPT1)

Involved in calcium binding and microtubule stabilization (By similarity).. Additionally we are shipping Tumor Protein, Translationally-Controlled 1 Antibodies (151) and Tumor Protein, Translationally-Controlled 1 Kits (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat TPT1 TPT1 100360791  
TPT1 7178 P13693
TPT1 22070 P63028
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Top Tumor Protein, Translationally-Controlled 1 Proteins at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$437.80
Details
Yeast Mouse His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$528.00
Details
Yeast Schistosoma mansoni His tag   1 mg Log in to see 56 to 66 Days
$2,379.67
Details
Yeast REACT_Alfalfa His tag   1 mg Log in to see 56 to 66 Days
$2,383.33
Details

TPT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , ,
,
Mouse (Murine) ,

Top referenced Tumor Protein, Translationally-Controlled 1 Proteins

  1. Human TPT1 Protein expressed in Escherichia coli (E. coli) - ABIN666938 : Vonakis, Macglashan, Vilariño, Langdon, Scott, MacDonald: Distinct characteristics of signal transduction events by histamine-releasing factor/translationally controlled tumor protein (HRF/TCTP)-induced priming and activation of human basophils. in Blood 2008 (PubMed)
    Show all 2 references for ABIN666938

  2. Human TPT1 Protein expressed in Wheat germ - ABIN1323472 : Sirois, Raymond, Brassard, Cailhier, Fedjaev, Hamelin, Londono, Bendayan, Pshezhetsky, Hébert: Caspase-3-dependent export of TCTP: a novel pathway for antiapoptotic intercellular communication. in Cell death and differentiation 2011 (PubMed)

  3. Human TPT1 Protein expressed in Escherichia coli (E. coli) - ABIN2006320 : Thaw, Baxter, Hounslow, Price, Waltho, Craven: Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones. in Nature structural biology 2001 (PubMed)

More Proteins for Tumor Protein, Translationally-Controlled 1 (TPT1) Interaction Partners

Fruit Fly (Drosophila melanogaster) Tumor Protein, Translationally-Controlled 1 (TPT1) interaction partners

  1. TCTP may promote the progression of epithelial ovarian cancer and reduce the sensitiveness of HO8910 cells to cisplatin.

  2. TCTP has a role in regulating ATM (show ATM Proteins) activity to control genome stability and organ development in Drosophila melanogaster

  3. Our studies identify TCTP as a direct regulator of Rheb (show RHEB Proteins) and a potential therapeutic target for tuberous sclerosis disease.

  4. Drosophila TCTP (dTCTP) displays GEF (show SLC2A4RG Proteins) activity to Rheb (show RHEB Proteins) and is essential for Rheb (show RHEB Proteins) activation in organ growth

Cow (Bovine) Tumor Protein, Translationally-Controlled 1 (TPT1) interaction partners

  1. pretreatment of donor cells with phosphorylated TCTP peptide has a beneficial effect on the potential of bovine somatic cell nuclei to develop into normal cloned calves.

Pig (Porcine) Tumor Protein, Translationally-Controlled 1 (TPT1) interaction partners

  1. A 'Y' transition single feature polymorphism in TCTP between Meishan and white composite swine breeds was identified by expression profiling using the in silico procedure Click-'N-SNP.

  2. This work describes the cloning and structural analysis of a Tpt1 cDNA coding for the porcine translationally controlled tumor protein (TCTP) molecule and its expression in porcine cells and tissues.

Silk Worm Tumor Protein, Translationally-Controlled 1 (TPT1) interaction partners

  1. BmTCTP as a dual-functional protein involved in both the cellular and the humoral immune response of the silkworm

Arabidopsis thaliana Tumor Protein, Translationally-Controlled 1 (TPT1) interaction partners

  1. TCTP has molecular properties similar to animal TCTPs, such as tubulin (show TUBB Proteins)- and calcium-binding, and that it functions in ABA-mediated stomatal movement, in addition to regulating the growth of plants.

  2. The results identify TCTP as an important regulator of growth in plants and imply a function of plant TCTP as a mediator of TOR activity similar to that known in nonplant systems.

Human Tumor Protein, Translationally-Controlled 1 (TPT1) interaction partners

  1. Downregulation of the expression of TCTP inhibits the migration and invasion of glioma cells.

  2. These data may suggest an involvement of translationally controlled tumor protein in normal physiology and carcinogenesis.

  3. High HRF expression is associated with non-Hodgkin lymphomas.

  4. Results demonstrate that TCTP mRNA translation is regulated by signalling through the PI3-K (show PIK3CA Proteins)/Akt (show AKT1 Proteins)/mTORC1 pathway in neoplasms.

  5. High phospho-TCTP expression levels are associated with aggressive breast cancer.

  6. TCTP binds to hemin and functions as a "buffer protein", controlling cellular homeostasis.

  7. analysis of how TCTP-PTD (show BCS1L Proteins) penetrates A549 human lung cancer cell membranes and promotes protein internalization

  8. Data indicate that Tanshinone IIA (Tan-IIA)T upregulated the protein expression of CHOP (show DDIT3 Proteins) and Bax (show BAX Proteins), but downregulated the protein expression of BiP (show GDF10 Proteins), TCTP, Mcl-1 (show MCL1 Proteins) and Bcl-xL (show BCL2L1 Proteins).

  9. Targeting Hsp27 (show HSPB1 Proteins) interaction with TCTP, a partner protein identified in a genetic screen, increases therapy sensitivity, and could decrease or abolish toxicity to normal cells.

  10. TCTP is functionally implicated in the progression of NF1 (show NF1 Proteins)-associated tumors.

Mouse (Murine) Tumor Protein, Translationally-Controlled 1 (TPT1) interaction partners

  1. results demonstrate that TCTP is a microtubule-associating protein required to regulate spindle microtubule dynamics during meiotic maturation in mouse oocytes.

  2. TCTP over-expression-induced RhoA (show RHOA Proteins) activation indicates that silencing of cellular TCTP may offer therapeutic approaches for the regulation of hypertension by inhibiting RhoA (show RHOA Proteins)/Rho kinase (show ROCK2 Proteins) pathway and modulating vascular contractility.

  3. osteoclastogenic activity of translationally-controlled tumor protein (TCTP) with reciprocal repression of p21

  4. TPT1 is a p53 (show TP53 Proteins) target gene that promotes cell survival.

  5. Fortilin, induced in the proatherosclerotic microenvironment in macrophages, protects macrophages against Bax (show BAX Proteins)-induced apoptosis, allows them to propagate, and accelerates atherosclerosis.

  6. Overexpression of translationally controlled tumor protein increases the severity of atherosclerosis and hypertension in apolipoprotein E (show APOE Proteins) knock-out mice

  7. These findings suggest that TCTP might play an important role in the process of podocyte hypertrophy under diabetic conditions via the regulation of mTORC1 activity and the induction of cell-cycle arrest.

  8. The TCTP downregulates the Oct4 (show POU5F1 Proteins) expression by binding the Sf1 (show SF1 Proteins) site of Oct4 (show POU5F1 Proteins) promoter in mouse pluripotent cells.

  9. TCTP may play a significant role in embryo implantation in mice

  10. knockdown of Tctp resulted in increased amounts of P53 (show TP53 Proteins) accompanied by a 50% reduction in the efficiency of tumor mammosphere formation

Xenopus laevis Tumor Protein, Translationally-Controlled 1 (TPT1) interaction partners

  1. Tctp supports the development of the retinotectal projection via its regulation of pro-survival signalling and axonal mitochondrial homeostasis, and establish a novel and fundamental role for Tctp in vertebrate neural circuitry assembly.

  2. Tpt1 activates transcription of oct4 and nanog in transplanted somatic nuclei.

Tumor Protein, Translationally-Controlled 1 (TPT1) Protein Profile

Protein Summary

Involved in calcium binding and microtubule stabilization (By similarity).

Gene names and symbols associated with TPT1

  • translationally controlled tumor-like protein (LOC548038)
  • Translationally controlled tumor protein (Tctp)
  • tumor protein, translationally-controlled 1 (tpt1)
  • tumor protein, translationally-controlled 1 (TPT1)
  • tumor protein, translationally-controlled 1 (LOC100294923)
  • tumor protein, translationally-controlled 1 (Tpt1)
  • tumor protein, translationally-controlled 1 (LOC100360791)
  • translationally controlled tumor protein (TCTP)
  • translationally controlled tumor protein (Tctp)
  • translationally controlled tumor protein-like protein (TCTP)
  • translationally-controlled tumor protein-like protein (TCTP)
  • CG4800 protein
  • Dmel\\CG4800 protein
  • dTCTP protein
  • fa28a02 protein
  • HRF protein
  • id:ibd2078 protein
  • MGC79720 protein
  • p02 protein
  • p21 protein
  • p23 protein
  • PCHK23 protein
  • TCT1 protein
  • tctp protein
  • Tpt1 protein
  • translationally controlled tumor protein protein
  • Trt protein
  • wu:fa28a02 protein

Protein level used designations for TPT1

translationally-controlled tumor protein homolog , CG4800-PA , Tctp-PA , translationally controlled tumor protein , tumor protein, translationally-controlled 1 , translationally-controlled tumor protein , bmTCTP , fortilin , histamine-releasing factor , p23 , 21 kDa polypeptide under translational control , translationally regulated transcript (21 kDa) , TCTP , lens epithelial protein , growth-related translationally controlled tumor protein , growth-related translationally-controlled tumor protein , translationally controlled tumor protein (TCTP) , translationally controlled tumor protein 3 , translationally controlled tumor protein 4

GENE ID SPECIES
548038 Glycine max
41341 Drosophila melanogaster
30723 Danio rerio
476924 Canis lupus familiaris
493436 Xenopus (Silurana) tropicalis
711798 Macaca mulatta
100294923 Bos taurus
100307058 Cavia porcellus
100360791 Rattus norvegicus
397664 Sus scrofa
732859 Bombyx mori
541981 Zea mays
820916 Arabidopsis thaliana
7178 Homo sapiens
22070 Mus musculus
116646 Rattus norvegicus
396363 Gallus gallus
326599 Bos taurus
100008854 Oryctolagus cuniculus
379839 Xenopus laevis
452575 Pan troglodytes
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