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TTYH1 encodes a member of the tweety family of proteins. Additionally we are shipping TTYH1 Antibodies (38) and many more products for this protein.
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In this report, we identify tweety-homolog 1 (Ttyh1), a membrane protein linked to neuronal development, as a potent driver of tumor microtube (TM)-mediated brain colonization by glioma cells.
Ttyh1 plays an indispensable role during mitosis in early embryogenesis, possibly by maintaining Ca(2 (show CA2 Proteins)+) homeostasis in the ER.
TTYH1 was not expressed in either the malignant or the control samples
Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific (show CALY Proteins) DNMT3B (show DNMT3B Proteins) isoform in the embryonal brain tumor.
Nedd4-2 (show NEDD4L Proteins) differentially interacts with and regulates TTYH1-3
While ttyh1 is restricted to proliferative, ventricular zones, ttyh3 (show TTYH3 Proteins) is primarily localized to postmitotic regions of the developing nervous system.
This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-independent, volume-sensitive large conductance chloride(-) channel. Three transcript variants encoding distinct isoforms have been identified for this gene.
, protein tweety homolog 1
, tweety homolog 1 (Drosophila)
, tweety 1
, protein tweety homolog 1-A