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UDP Glucuronosyltransferase 2 Family, Polypeptide B15 Proteins (UGT2B15)

UGT2B15 encodes a member of the UDP-glycosyltransferase (UDPGT) family. Additionally we are shipping UDP Glucuronosyltransferase 2 Family, Polypeptide B15 Antibodies (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UGT2B15 7366 P54855
Rat UGT2B15 UGT2B15 83808  
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Top UDP Glucuronosyltransferase 2 Family, Polypeptide B15 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

UGT2B15 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) Interaction Partners

Human UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) interaction partners

  1. CYP3A4 (show CYP3A4 Proteins), CYP3A7 (show CYP3A7 Proteins), UGT2B11 and UGT2B15 genes are significantly downregulated in melanosis coli.

  2. This descriptive study examines correlations between concentrations of tamoxifen's glucuronide metabolites and genotypes UGT1A4 (show UGT1A4 Proteins), UGT2B7, UGT2B15 and UGT2B17 in 132 patients with estrogen receptor (show ESR1 Proteins)-positive breast cancer under treatment with tamoxifen

  3. miR (show MLXIP Proteins)-376c is inversely linked to UGT2B15 and UGT2B17 expression in high-grade prostate cancer and metastasis.UGT2B15 and UGT2B17 genes are direct targets of miR (show MLXIP Proteins)-376c and thus may influence steroid metabolism during prostate cancer progression.

  4. Data suggest that both 17beta-estradiol and the antiestrogen 4-OHTAM (4-hydroxytamoxifen, a metabolite of tamoxifen and substrate of UGT2B15) up-regulate UGT2B15 in breast cancer cells via the same estrogen receptor alpha (show ESR1 Proteins)- (ERa-)signaling pathway.

  5. Hepatic UGT2B15 protein onset begins in late gestation; however, the greatest rate of change occurs during the first few weeks after birth.

  6. Expression of UGT2B15 and UGT2B17 is negatively regulated by the binding of miR (show MLXIP Proteins)-376c.

  7. UGT2B15 genotype is a major determinant for differences in fasting plasma glucose and HbA1c response to sipoglitazar treatment between Type 2 Diabetes mellitus patients, due to related differences in drug exposure.

  8. A haplotype in UGT2B15 containing a functional variant (rs4148269, K523T) and an intronic SNP (rs6837575) was found to affect rectal cancer risk overall (OR = 2.57, 95% CI = 1.21-5.04) and in females (OR = 3.08, 95% CI = 1.08-8.74).

  9. In the tamoxifen-treated subgroup poor prognosis was related to the combined presence of ESR1 (show ESR1 Proteins) PvuII wt/wt and UGT2B15 wt/wt or wt/*2 genotype.

  10. Novel associations between UGT2B15 and UGT2B17 single nucleotide polymorphism variants and prostate cancer risk.

UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) Protein Profile

Protein Summary

This gene encodes a member of the UDP-glycosyltransferase (UDPGT) family. The UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein displays activity towards several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens.

Gene names and symbols associated with UGT2B15

  • UDP glucuronosyltransferase 2 family, polypeptide B15 (UGT2B15)
  • UDP glucuronosyltransferase 2 family, polypeptide B4 (UGT2B4)
  • UDP glucuronosyltransferase 2 family, polypeptide B15 (Ugt2b15)
  • HLUG4 protein
  • UDPGT 2B8 protein
  • UDPGT2B15 protein
  • UDPGTH3 protein
  • Ugt2b4 protein
  • UGT2B8 protein
  • Ugt2b12 protein
  • UGT2B15 protein
  • UGT2B28 protein
  • Ugt2b36 protein

Protein level used designations for UGT2B15

UDP glycosyltransferase 2 family, polypeptide B28 , UDP glucuronosyltransferase 2 family, polypeptide B15 , UDP glucuronosyltransferase 2 family, polypeptide B4 , UDP glucuronosyltransferase 2 family, polypeptide B17-like , UDP glycosyltransferase 2B15 , UDP-glucuronosyltransferase 2B15 , UDP-glucuronosyltransferase 2B8 , UDP-glucuronosyltransferase UGT2B15 , UDP-glucuronyltransferase, family 2, beta-15 , UDPGT 2B15 , UDPGTh-3 , UDP glucuronosyltransferase 2 family, polypeptide B36 , UDP glycosyltransferase 2 family, polypeptide B4 , UDP-glucuronosyltransferase 2B12 , UDP-glucuronosyltransferase 2B36 , UDP-glucuronosyltransferase 2B4 , UDPGT 2B12 , UDPGT 2B36 , UDPGT 2B4

GENE ID SPECIES
461289 Pan troglodytes
480777 Canis lupus familiaris
540544 Bos taurus
710412 Macaca mulatta
100591991 Nomascus leucogenys
7366 Homo sapiens
83808 Rattus norvegicus
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