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anti-UDP-Glucose 6-Dehydrogenase (UGDH) Antibodies

The protein encoded by UGDH converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. Additionally we are shipping UGDH Proteins (16) and UGDH Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UGDH 7358 O60701
UGDH 83472 O70199
UGDH 22235 O70475
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Top anti-UGDH Antibodies at antibodies-online.com

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB UGDH Antibody (C-term) (ABIN656544) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB UGDH Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of UGDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. UGDH Antibody (C-term) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the UGDH antibody detected the UGDH protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: Ugdh  Sample Tissue: Rat Stomach lysates  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-UGDH AntibodyTitration: 1.0 µg/mL  Positive Control: HepG2 Whole Cell  UGDH is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COLO cells, using UGDH Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image UGDH antibody detects UGDH protein by Western blot analysis. A. 30 µg HepG2 whole cell lysate/extract 7.5 % SDS-PAGE UGDH antibody , dilution: 1:10000 IHC-P Image UGDH antibody detects UGDH protein at cytosol on human hepatoma by immunohistochemical analysis. Sample: Paraffin-embedded hepatoma tissue. UGDH antibody , dilution: 1:500. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Cow Rabbit Biotin DB, EIA, ID, IF, IP, RIA, WB   1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Mouse Rabbit Un-conjugated IHC, WB Immunofluorescence analysis of HeLa cell using UGDH antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 9 Days
$302.50
Details

UGDH Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-UGDH Antibodies

  1. Human Polyclonal UGDH Primary Antibody for EIA, IHC (p) - ABIN955441 : Wang, Pan, Fu, Chang: Down-regulation of UDP-glucose dehydrogenase affects glycosaminoglycans synthesis and motility in HCT-8 colorectal carcinoma cells. in Experimental cell research 2010 (PubMed)
    Show all 4 references for ABIN955441

  2. Human Polyclonal UGDH Primary Antibody for IHC (p), WB - ABIN656544 : Huang, Casale, Tian, Lele, Pisarev, Simpson, Hemstreet: Udp-glucose dehydrogenase as a novel field-specific candidate biomarker of prostate cancer. in International journal of cancer. Journal international du cancer 2009 (PubMed)

More Antibodies against UGDH Interaction Partners

Xenopus laevis UDP-Glucose 6-Dehydrogenase (UGDH) interaction partners

  1. UDP-glucose dehydrogenase has a role in hyaluronan synthesis

Human UDP-Glucose 6-Dehydrogenase (UGDH) interaction partners

  1. UGDH protein level in osteoarthritis cartilage was much lower than in control cartilage.

  2. UGDH displays hysteresis because of a slow isomerization from an inactive state (E*) to an active state (E). We show that the structure of E* constrains UGDH in a conformation that favors feedback inhibition at physiological pH.

  3. Kinetic analysis of wild-type UGDH and hexamer T325A showed that upon increasing enzyme concentration, which favors the hexameric species, activity was decreased and exhibited cooperativity. Cooperative kinetics was not observed in obligate dimer T325D.

  4. Mammalian UGDH displays hysteresis (observed as a lag (show STMN1 Antibodies) in progress curves), indicating that the enzyme undergoes a slow transition from an inactive to an active state. Human UGDH is sensitive to product inhibition during the lag (show STMN1 Antibodies).

  5. both missense mutations significantly reducing the ability of UGDH to provide precursors for cardiac cushion formation, which is essential to subsequent valve formation.

  6. Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates.

  7. An alternate crystal structure of human UGDH (hUGDH) in complex with UDP-glucose (show UGCG Antibodies) at 2.8 A resolution, is reported.

  8. A structurally detailed model of UDP-alpha-D-glucose 6-dehydrogenase (UGDH) demonstrates hinge-bending motion that represents allosteric feedback inhibition and substrate-product exchange during the catalytic cycle.

  9. high UGDH levels may underlie susceptibility of the orbit to localized overproduction of hyaluronan in Graves disease.

  10. Structure and mechanism of human UDP-glucose 6-dehydrogenase.

Mouse (Murine) UDP-Glucose 6-Dehydrogenase (UGDH) interaction partners

  1. Six proteins were regulated at both basal and inducible levels exhibiting the largest dynamic range of Nrf2 (show NFE2L2 Antibodies) regulation: cytochrome CYP2A5, GSTM3 (show glutathione S-transferase mu 3 (brain) Antibodies), GSTM1 (show GSTM1 Antibodies), ENTPD5 (show ENTPD5 Antibodies),UDPGDH, and EPHX1 (show EPHX1 Antibodies).

UGDH Antigen Profile

Protein Summary

The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with UGDH

  • sugarless (sgl) antibody
  • UDP-glucose dehydrogenase (ugdh) antibody
  • UDP-glucose 6-dehydrogenase (ugdh-b) antibody
  • UDP-glucose 6-dehydrogenase (UGDH) antibody
  • UDP-glucose 6-dehydrogenase (ugdh) antibody
  • UDP-glucose 6-dehydrogenase (ugdh-a) antibody
  • UDP-glucose 6-dehydrogenase (hasB) antibody
  • UDP-glucose 6-dehydrogenase (ugdH) antibody
  • UDP-glucose 6-dehydrogenase (ugd) antibody
  • UDP-glucose 6-dehydrogenase (SCO3052) antibody
  • UDP-glucose 6-dehydrogenase (CNL06460) antibody
  • UDP-glucose 6-dehydrogenase (Ugdh) antibody
  • UDP-glucose dehydrogenase (Ugdh) antibody
  • 8310 antibody
  • AGR_L_1413 antibody
  • BA5434 antibody
  • BG01214 antibody
  • CG10072 antibody
  • Dmel\\CG10072 antibody
  • GDH antibody
  • ik:tdsubc_2a8 antibody
  • kiwi antibody
  • l(3)05007 antibody
  • l(3)08310 antibody
  • l(3)65CEd antibody
  • l(3)10503 antibody
  • l(3)SG9 antibody
  • SCBAC19G2.07 antibody
  • Sgl antibody
  • ska antibody
  • sl antibody
  • tdsubc_2a8 antibody
  • udg antibody
  • UDP-GlcDH antibody
  • udpg antibody
  • Udpgdh antibody
  • UGD antibody
  • ugdh antibody
  • ugdha antibody
  • ugdhb antibody
  • XIII antibody
  • xugdh antibody
  • xx:tdsubc_2a8 antibody

Protein level used designations for UGDH

CG10072-PA , UDP-glucose 6-dehydrogenase , UDP-glucose dehydrogenase , distal W5.4 group XIII , kiwi , lethal(3)SG9 , sgl-PA , suppenkasper , jek , jekyll , UDP-glucose dehydrogenase b , UDP-glucose dehydrogenase a , UDP-Glc dehydrogenase , uridine diphospho-glucose dehydrogenase , UDP-GlcDH , UDP-glucose dehydrogeanse , UDPGDH

GENE ID SPECIES
38760 Drosophila melanogaster
116991 Danio rerio
379152 Xenopus laevis
471171 Pan troglodytes
541452 Xenopus (Silurana) tropicalis
734199 Xenopus laevis
901876 Streptococcus pyogenes M1 GAS
994258 Streptococcus pyogenes MGAS8232
1048955 Bradyrhizobium diazoefficiens USDA 110
1050618 Bradyrhizobium diazoefficiens USDA 110
1085034 Bacillus anthracis str. Ames
1098485 Streptomyces coelicolor A3(2)
1136023 Agrobacterium fabrum str. C58
1172269 Shewanella oneidensis MR-1
1208739 Coxiella burnetii RSA 493
1248624 Salmonella enterica subsp. enterica serovar Typhi str. CT18
1796512 Rhodopirellula baltica SH 1
2686288 Geobacter sulfurreducens PCA
3104468 Methylococcus capsulatus str. Bath
3176517 Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
3255012 Cryptococcus neoformans var. neoformans JEC21
7386467 Agrobacterium vitis S4
10978101 Zobellia galactanivorans
100016058 Monodelphis domestica
100055067 Equus caballus
100174620 Pongo abelii
100355018 Oryctolagus cuniculus
7358 Homo sapiens
83472 Rattus norvegicus
281564 Bos taurus
479107 Canis lupus familiaris
100627727 Sus scrofa
422792 Gallus gallus
22235 Mus musculus
Selected quality suppliers for anti-UGDH (UGDH) Antibodies
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