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UPF3B Proteins

(UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
UPF3B Protein (AA 1-483) (His tag) UPF3B Protein (AA 1-483) (His tag) UPF3B Protein (AA 1-483) (His tag) (ABIN3094948)

Crystallography grade UPF3B Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA

UPF3B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) UPF3B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) UPF3B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2735037)

UPF3B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

UPF3B Proteins by Grade

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UPF3B Proteins by Origin

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UPF3B Proteins by Source

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UPF3B Proteins by Protein Type

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UPF3B Proteins by Application

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Popular UPF3B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3094948
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2735037
Quantity 20 μg
Datasheet Datasheet

Aliases for UPF3B Proteins

UPF3B, regulator of nonsense mediated mRNA decay (UPF3B) Proteins
UPF3 regulator of nonsense transcripts homolog B (yeast) (Upf3b) Proteins
UPF3B, regulator of nonsense mediated mRNA decay (Upf3b) Proteins
5730594O13Rik Proteins
AI317193 Proteins
AW541158 Proteins
HUPF3B Proteins
MRXS14 Proteins
RENT3B Proteins
RGD1560264 Proteins
UPF3X Proteins
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