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Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1) ELISA Kits

The N-end rule pathway is one proteolytic pathway of the ubiquitin system. Additionally we are shipping UBR1 Antibodies (49) and UBR1 Proteins (2) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
UBR1 197131 Q8IWV7
UBR1 22222 O70481
Anti-Rat UBR1 UBR1 499877  
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Top UBR1 ELISA Kits at antibodies-online.com

Showing 2 out of 4 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.156-10 ng/mL 96 Tests Log in to see 11 to 13 Days
$875.60
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details

More ELISA Kits for UBR1 Interaction Partners

Human Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1) interaction partners

  1. Reduced UBR1 expression affects MGMT (show MGMT ELISA Kits) turnover and DNA repair in the smokers lungs.

  2. For all previously reported and novel UBR1 mutations together with their clinical data, a mutation database has been established at LOVD.

  3. Testing the fetus and the affected sibling with recurrent Johanson-Blizzard syndrome revealed a homozygous truncating mutation in UBR1.

  4. Results confirmed the relevance of specific missense UBR1 alleles to JBS, and suggested that a residual activity of a missense allele is causally associated with milder variants of JBS.

  5. Molecular studies revealed a novel homozygous nonsense mutation in exon 38 of the UBR1 gene, which confirmed the diagnosis of Johanson-Blizzard syndrome.

  6. Ubc2 (show ube2a ELISA Kits)/Rad6 ser (show SIGLEC1 ELISA Kits)(120) regulates ubiquitin-dependent N-end rule targeting by E3{alpha}/Ubr1

  7. Deficiency of UBR1 perturbs the pancreas' acinar cells and other organs, presumably owing to metabolic stabilization of specific substrates of the N-end rule pathway.

  8. Sustained ERK5 activity and the E3 ligase UBR1 regulate the stability and subcellular localization of c-Fos.

  9. Thus we propose that autoISGylation of EFP (show TRIM25 ELISA Kits) negatively regulates its ISG15 (show ISG15 ELISA Kits) E3 ligase activity for 14-3-3sigma.

  10. These results suggest that Rabring7 is involved in the endocytic trafficking of EGFR (show EGFR ELISA Kits) through its E3 ligase activity.

Mouse (Murine) Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1) interaction partners

  1. involved in learning and memory; behavioral characterizations of UBR1 knockout mice

  2. UBR1-/-UBR2 (show UBR2 ELISA Kits)-/- embryos die at midgestation, with defects in neurogenesis and cardiovascular development.

  3. TLX1/HOX11 (show TLX1 ELISA Kits) overexpression and Ubr1 inactivation in promoting chromosome missegregation, permitting the accrual of additional chromosome losses and cytogenic abnormalities en route to malignancy

  4. A STAT3 (show STAT3 ELISA Kits)-dependent E3 ubiquitin ligase, Ubr1, was responsible for rhodopsin (show RHO ELISA Kits) degradation and was up-regulated in the inflamed SOCS3 (show SOCS3 ELISA Kits)-deficient retinas.

UBR1 Antigen Profile

Antigen Summary

The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.

Gene names and symbols associated with UBR1

  • CG9086 gene product from transcript CG9086-RB (CG9086) antibody
  • ubiquitin protein ligase E3 component n-recognin 1 (ubr1) antibody
  • ubiquitin protein ligase E3 component n-recognin 1 (UBR1) antibody
  • Protein UBR-1 (ubr-1) antibody
  • ubiquitin protein ligase E3 component n-recognin 1 (Ubr1) antibody
  • AI504731 antibody
  • Dmel\\CG9086 antibody
  • JBS antibody
  • RGD1562326 antibody
  • UBR1 antibody

Protein level used designations for UBR1

CG9086-PA , CG9086-PB , ubiquitin protein ligase E3 component n-recognin 1 , E3 ubiquitin-protein ligase UBR1 , E3a ligase , N-recognin-1 , ubiquitin ligase E3 alpha-I , ubiquitin-protein ligase E3-alpha , ubiquitin-protein ligase E3-alpha-1 , ubiquitin-protein ligase E3-alpha-I , E3 alpha , ubiquitin-protein ligase e3 componen n-recognin

GENE ID SPECIES
32687 Drosophila melanogaster
568531 Danio rerio
100010751 Monodelphis domestica
100056497 Equus caballus
100511299 Sus scrofa
100558444 Anolis carolinensis
171953 Caenorhabditis elegans
197131 Homo sapiens
22222 Mus musculus
487521 Canis lupus familiaris
522464 Bos taurus
499877 Rattus norvegicus
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