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anti-Ubiquitin Specific Peptidase 22 (USP22) Antibodies

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Additionally we are shipping USP22 Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
USP22 23326 Q9UPT9
USP22 216825 Q5DU02
USP22 303201  
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Top anti-USP22 Antibodies at antibodies-online.com

Showing 10 out of 71 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-USP22 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-USP22 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human heart Host: Rabbit   Target Name: USP22   Sample Tissue: Human Fetal Lung  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of USP22 Antibody (C-term) (ABIN388914) in Jurkat cell line lysates (35 µg/lane). USP22 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of USP22 Antibody (N-term) (ABIN388913) in Jurkat cell line lysates (35 µg/lane).USP22(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB USP22 Antibody (C-term) (ABIN1882289) western blot analysis in Daudi cell line lysates (35 µg/lane). This demonstrates the USP22 antibody detected the USP22 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

USP22 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-USP22 Antibodies

  1. Human Monoclonal USP22 Primary Antibody for WB - ABIN1882289 : Bechtel, Rosenfelder, Duda, Schmidt, Ernst, Wellenreuther, Mehrle, Schuster, Bahr, Blöcker, Heubner, Hoerlein, Michel, Wedler, Köhrer, Ottenwälder, Poustka, Wiemann, Schupp: The full-ORF clone resource of the German cDNA Consortium. in BMC genomics 2008 (PubMed)
    Show all 5 references for ABIN1882289

  2. Cow (Bovine) Polyclonal USP22 Primary Antibody for WB - ABIN2787646 : Zhang, Varthi, Sykes, Phillips, Warzecha, Zhu, Wyce, Thorne, Berger, McMahon: The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression. in Molecular cell 2008 (PubMed)

  3. Human Polyclonal USP22 Primary Antibody for IHC (p), WB - ABIN388914 : Wang, Zhu, Guo, Wang, Yang: Decreased H2B monoubiquitination and overexpression of ubiquitin-specific protease enzyme 22 in malignant colon carcinoma. in Human pathology 2015 (PubMed)

  4. Human Polyclonal USP22 Primary Antibody for WB - ABIN388913 : Hong, Lee, Chung: Ubiquitin-specific protease 22 (USP22) positively regulates RCAN1 protein levels through RCAN1 de-ubiquitination. in Journal of cellular physiology 2015 (PubMed)

  5. Human Polyclonal USP22 Primary Antibody for EIA, IHC (p) - ABIN357559 : Kikuno, Nagase, Ishikawa, Hirosawa, Miyajima, Tanaka, Kotani, Nomura, Ohara: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. in DNA research : an international journal for rapid publication of reports on genes and genomes 1999 (PubMed)

More Antibodies against USP22 Interaction Partners

Fruit Fly (Drosophila melanogaster) Ubiquitin Specific Peptidase 22 (USP22) interaction partners

  1. Loss of Ataxin-7 (show ATXN7 Antibodies) results in a toxic gain of activity of the Non-stop deubiquitinase.

  2. Data establish that Nonstop actually functions as an ubiquitin (show UBA52 Antibodies) protease to control the levels of ubiquitinated histone H2B in flies. We further establish that Nonstop is the functional homolog of yeast Ubp8

  3. 3 additional subunits of TFTC/STAGA (dSgf11, non-stop, & en(y)2) help form the deubiquitination module. This module is an enhancer of position effect variegation in Drosophila.

Human Ubiquitin Specific Peptidase 22 (USP22) interaction partners

  1. findings suggest that USP22 may be involved in hepatocellular carcinoma progression in cooperation with survivin (show BIRC5 Antibodies).

  2. These findings provide evidence that high USP22 expression might be important in tumor progression and serves as an independent molecular marker for poor hepatocellular carcinoma prognosis

  3. USP22 attenuated the invasion capacity of colon cancer cells by inhibiting the STAT3 (show STAT3 Antibodies)/MMP9 (show MMP9 Antibodies) signaling pathway.

  4. Our data indicated that USP22 may promote lung adenocarcinoma cell invasion by the induction of EMT (show ITK Antibodies).

  5. Data show that the aggregates formed by polyQ-expanded ataxin 7 (show ATXN7 Antibodies) sequester ubiquitin-specific protease (USP22) through specific interactions.

  6. the deubiquitinating enzyme activity of USP22 is necessary for regulating HeLa cell growth, and it promotes cell proliferation via the c-Myc (show MYC Antibodies)/cyclin D2 (show CCND2 Antibodies), BMI-1 (show BMI1 Antibodies) and p53 (show TP53 Antibodies) pathways in HeLa cells

  7. ShRNA-mediated silencing of the ubiquitin-specific protease 22 gene restrained cell progression and affected the Akt (show AKT1 Antibodies) pathway in nasopharyngeal carcinoma.

  8. Data indicate that ubiquitin specific peptidase 22 (USP22)-mediated sirtuin 1 (SIRT1 (show SIRT1 Antibodies)) deubiquitination inhibits STAT3 (show STAT3 Antibodies) transcription factor acetylation and its transcriptional activation.

  9. USP22 is overexpressed in human NSCLC tissues and cell lines. USP22 silencing downregulates MDMX protein (show MDM4 Antibodies) expression and activates the p53 (show TP53 Antibodies) pathway.

  10. Increased USP22 expression in colon cancer correlated with reduced uH2B expression, and this expression pattern may contribute to tumor progression.

Mouse (Murine) Ubiquitin Specific Peptidase 22 (USP22) interaction partners

  1. Usp22 deficiency impairs intestinal epithelial lineage specification.

  2. USP22 is a transcriptional repressor of the locus encoding the core pluripotency factor sex-determining region Y-box 2 (SOX2 (show SOX2 Antibodies)) in embryonic stem cells.

  3. Genetic deletion of the usp22 gene results in Sirt1 (show SIRT1 Antibodies) instability, elevated p53 (show TP53 Antibodies) transcriptional activity and early embryonic lethality.

USP22 Antigen Profile

Protein Summary

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators, where it is required for transcription (By similarity).

Gene names and symbols associated with USP22

  • ubiquitin specific peptidase 22 (USP22) antibody
  • ubiquitin specific peptidase 22 (usp22) antibody
  • non-stop (not) antibody
  • hypothetical LOC454511 (USP22) antibody
  • ubiquitin specific protease 22 (USP22) antibody
  • universal stress protein (usp22) antibody
  • ubiquitin specific peptidase 22 (Usp22) antibody
  • AI427806 antibody
  • anon-WO0257455.9 antibody
  • CG4166 antibody
  • Dmel\\CG4166 antibody
  • i155 antibody
  • l(3)02069 antibody
  • l(3)j9A6 antibody
  • nonstop antibody
  • NOT antibody
  • UBP8 antibody
  • Upb8 antibody
  • USP3L antibody
  • USP22 antibody
  • zgc:136342 antibody

Protein level used designations for USP22

ubiquitin specific peptidase 22 , ubiquitin thiolesterase 22 , ubiquitin carboxyl-terminal hydrolase 22-like , CG4166-PB , nonstop , not-PB , ubiquitin specific protease 22 , universal stress protein , deubiquitinating enzyme 22 , ubiquitin carboxyl-terminal hydrolase 22 , ubiquitin thioesterase 22 , ubiquitin-specific processing protease 22 , ubiquitin-specific-processing protease 22

GENE ID SPECIES
712098 Macaca mulatta
100053238 Equus caballus
100340977 Oryctolagus cuniculus
100379835 Xenopus (Silurana) tropicalis
100456449 Pongo abelii
100476428 Ailuropoda melanoleuca
40030 Drosophila melanogaster
454511 Pan troglodytes
694018 Macaca mulatta
3129313 Haloarcula marismortui ATCC 43049
23326 Homo sapiens
216825 Mus musculus
692275 Danio rerio
509694 Bos taurus
303201 Rattus norvegicus
416501 Gallus gallus
609588 Canis lupus familiaris
Selected quality suppliers for anti-USP22 (USP22) Antibodies
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