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anti-Ubiquitin-Conjugating Enzyme E2I (UBE2I) Antibodies

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2I Proteins (35) and Ubiquitin-Conjugating Enzyme E2I Kits (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBE2I 7329 P63279
UBE2I 22196 P63280
UBE2I 25573 P63281
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Top anti-Ubiquitin-Conjugating Enzyme E2I Antibodies at antibodies-online.com

Showing 10 out of 111 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Goat Un-conjugated EIA, IHC (p), WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-UBE2I Antibody (N-term) (ABIN387910) in A2058 cell line lysates (35 µg/lane). UBE2I(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Goat Un-conjugated EIA, IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-UBE2I Antibody Titration: 2.5ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-UBE2I Antibody Titration: 2.5ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN184894 (0.1 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN184894 (0.3 ug/ml) staining of paraffin embedded Human Kidney.  Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated WB (LEFT) Western blot analysis of anti-UBC9 Antibody (ABIN387788) in Ramos cell line lysates (35 µg/lane). UBC9(arrow) was detected using the purified Mab. (RIGHT) Western blot analysis of anti-UBC9 Antibody (C-term) (ABIN387788) in mouse spleen tissue lysates (35 µg/lane). UBC9(arrow) was detected using the purified Mab. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Chicken Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of Ubc9 on human endothelial lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of Ubc9. Human Endothelial 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of HepG2 cells using UBE2I mouse mAb (green) and negative control (red) . 100 μL Log in to see 3 to 4 Days
$430.10
Details

UBE2I Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-Ubiquitin-Conjugating Enzyme E2I Antibodies

  1. Human Monoclonal UBE2I Primary Antibody for WB - ABIN387788 : Moschos, Jukic, Athanassiou, Bhargava, Dacic, Wang, Kuan, Fayewicz, Galambos, Acquafondata, Dhir, Becker: Expression analysis of Ubc9, the single small ubiquitin-like modifier (SUMO) E2 conjugating enzyme, in normal and malignant tissues. in Human pathology 2010 (PubMed)
    Show all 7 references for ABIN387788

  2. Chicken Monoclonal UBE2I Primary Antibody for IF, IP - ABIN968154 : Buschmann, Lerner, Lee, Ronai: The Mdm-2 amino terminus is required for Mdm2 binding and SUMO-1 conjugation by the E2 SUMO-1 conjugating enzyme Ubc9. in The Journal of biological chemistry 2001 (PubMed)
    Show all 4 references for ABIN968154

  3. Dog (Canine) Polyclonal UBE2I Primary Antibody for EIA, IHC (p) - ABIN782921 : Ihara, Stein, Schultz: UBE2I (UBC9), a SUMO-conjugating enzyme, localizes to nuclear speckles and stimulates transcription in mouse oocytes. in Biology of reproduction 2008 (PubMed)
    Show all 3 references for ABIN782921

  4. Dog (Canine) Polyclonal UBE2I Primary Antibody for EIA, IF - ABIN374291 : Wang, Qiu, Seufert, Taguchi, Testa, Whitmore, Callen, Welsh, Shenk, Deuel: Molecular cloning of the cDNA and chromosome localization of the gene for human ubiquitin-conjugating enzyme 9. in The Journal of biological chemistry 1996 (PubMed)
    Show all 3 references for ABIN374291

  5. Human Polyclonal UBE2I Primary Antibody for IHC (p), WB - ABIN387910 : Watanabe, Fujiwara, Kawai, Shimizu, Takami, Hirano, Okuno, Ozaki, Takeda, Shimada, Nagata, Takaichi, Takahashi, Nakamura, Shin: Cloning, expression, and mapping of UBE2I, a novel gene encoding a human homologue of yeast ubiquitin-conjugating enzymes which are critical for regulating the cell cycle. in Cytogenetics and cell genetics 1996 (PubMed)
    Show all 3 references for ABIN387910

  6. Human Monoclonal UBE2I Primary Antibody for ICC, FACS - ABIN969451 : Mohideen, Capili, Bilimoria, Yamada, Bonni, Lima: A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9. in Nature structural & molecular biology 2009 (PubMed)
    Show all 2 references for ABIN969451

  7. Human Polyclonal UBE2I Primary Antibody for EIA, IHC (p) - ABIN356594 : Tachibana, Iwata, Watanabe, Nobukuni, Ploplis, Kajigaya: Assignment of the gene for a ubiquitin-conjugating enzyme (UBE2I) to human chromosome band 16p13.3 by in situ hybridization. in Cytogenetics and cell genetics 1997 (PubMed)
    Show all 2 references for ABIN356594

  8. Chicken Polyclonal UBE2I Primary Antibody for WB - ABIN2775681 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)

  9. Chicken Polyclonal UBE2I Primary Antibody for WB - ABIN2775680 : Zhu, Zhang, Matunis: SUMO modification through rapamycin-mediated heterodimerization reveals a dual role for Ubc9 in targeting RanGAP1 to nuclear pore complexes. in Experimental cell research 2006 (PubMed)

More Antibodies against Ubiquitin-Conjugating Enzyme E2I Interaction Partners

Pig (Porcine) Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. Analysis of protein interactions showed that K179A, K180A, and K221A substitutions of classical swine fever virus core protein disrupt core-SUMO-1 (show SUMO1 Antibodies) binding, while K220A substitution precludes core-UBC9 binding.

Caenorhabditis elegans (C. elegans) Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. TBX-2 (show TBX2 Antibodies) and SUMO-conjugating enzymes are necessary for ABa-derived pharyngeal muscle, and we hypothesize that TBX-2 (show TBX2 Antibodies) function requires sumoylation.

Human Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. Suggest a novel role of PCGF2 (show PCGF2 Antibodies) in arsenic trioxide-mediated degradation of PML (show PML Antibodies)-RARA (show RARA Antibodies) that PCGF2 (show PCGF2 Antibodies) might act as a negative regulator of UBE2I via direct interaction.

  2. Akt (show AKT1 Antibodies) directly phosphorylates Ubc9 at Thr35 and phosphorylates SUMO1 (show SUMO1 Antibodies) at Thr76. Ubc9 phosphorylation at Thr35 promotes Ubc9 thioester bond formation and SUMO1 (show SUMO1 Antibodies) phosphorylation at Thr76 stabilizes the SUMO1 (show SUMO1 Antibodies) protein.

  3. Characterization and Structural Insights into Selective E1-E2 Interactions in the Human and Plasmodium falciparum SUMO Conjugation Systems.

  4. a high-throughput microscopy screen identified ubiquitin carrier protein 9 (Ubc9) as a negative regulator of energy storage in human sc adipocytes. Ubc9 depletion enhanced energy storage and induced the brown fat gene program in human sc adipocytes.

  5. The authors show that ZNF451 is SUMO2 specific and that SUMO modification of ZNF451 may contribute to activity by providing a second molecule of SUMO that interacts with E2.

  6. The RWD domain binds to a Ubc9 surface that also must interact with E1, E3, and SUMO.

  7. These data show that NS5A is a target protein of small ubiquitin-like modifier (SUMO (show SUMO1 Antibodies)) and is SUMOylated at lysine residue 348 and silencing of UBC9 impaired hepatitis C virus replication.

  8. SUMO E2 ligase Ubc9 has a critical role in oncogenesis driven by the Ras/Raf (show RAF1 Antibodies) pathway

  9. Ubc9 gene plays an important role in cell proliferation in epithelial ovarian cancer through PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway.

  10. Data indicate that protein tyrosine phosphatase 1B (PTP1B (show PTPN1 Antibodies)) association with calnexin (show CANX Antibodies) is ubiquitin conjugating enzyme 9 (UBC9)-dependent.

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. The study reveals a function of SUMO protein modification as a Ubiquitin-independent ESCRT sorting signal, regulating the extracellular vesicle release of alpha-Synuclein (show SNCA Antibodies).

  2. Synaptic trapping of Ubc9 through a PKC (show PKC Antibodies) phosphorylation-dependent increase of Ubc9 recognition to phosphorylated substrates and consequently leads to the modulation of synaptic sumoylation.

  3. UBC9 has a role in promoting proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis

  4. the sole SUMO E2 enzyme Ubc9 plays a critical role in reprogramming fibroblasts to iPS cells and maintaining ESC pluripotency.

  5. Data indicate that knockdown of ubiquitin-conjugating enzyme 9 (UBC9) by small interfering RNA caused significant accumulations of aggregated protein.

  6. Ubc9 negatively regulates osteoblastic differentiation induced by BMP.

  7. expressed Ubc9 at modestly increased levels showed robust resistance to brain ischemia compared to wild type mice

  8. Ubiquitous loss of sumoylation due to loss of UBC9 led to immediate fatal failure of intestinal function. Sumoylation was required for nucleus positioning and polarized organization of actin in the enterocytes.

  9. FOXL2 (show FOXL2 Antibodies) interacts with PIAS1 (show PIAS1 Antibodies) and UBC9, and sumoylated in both human and mouse

  10. The temporal profile of UBC9 induction and its ability to affect C/EBPdelta (show CEBPD Antibodies) mRNA induction support a role for this protein during early adipogenesis

Zebrafish Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. These data indicate an in vivo requirement of Ubc9 for G2/M transition and/or progression through mitosis during vertebrate organogenesis.

Cow (Bovine) Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. Chromosomal assignment of the bovine ubiquitin-conjugating enzyme E2I (UBE2I ) gene to BTA6q34 defines a new fragment of conserved synteny with human chromosome 16.

Ubiquitin-Conjugating Enzyme E2I (UBE2I) Antigen Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with UBE2I

  • ubiquitin-conjugating enzyme E2L (UBE2L) antibody
  • ubiquitin-conjugating enzyme E2I (LOC100358924) antibody
  • ubiquitin-conjugating enzyme E2I (UBE2I) antibody
  • Protein UBC-9 (ubc-9) antibody
  • ubiquitin conjugating enzyme 9 (UBC9) antibody
  • ubiquitin-conjugating enzyme E2I (Ube2i) antibody
  • ubiquitin-conjugating enzyme E2I (ube2i) antibody
  • 5830467E05Rik antibody
  • C358B7.1 antibody
  • F830028O17Rik antibody
  • P18 antibody
  • T13J8.70 antibody
  • T13J8_70 antibody
  • ubc9 antibody
  • UbcE2A antibody
  • Ubce2i antibody
  • ubce9 antibody
  • ube2ia antibody
  • UBIQUITIN-PROTEIN LIGASE antibody
  • ubiquitin conjugating enzyme 9 antibody
  • zUbc9 antibody

Protein level used designations for UBE2I

ubiquitin-conjugating enzyme E2L , ubiquitin-conjugating enzyme E2I , SUMO-conjugating enzyme UBC9 , SUMO-1 conjugating enzyme , ubiquitin conjugating enzyme 9 , ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) , SUMO-1-protein ligase , SUMO-protein ligase , ubiquitin carrier protein 9 , ubiquitin carrier protein I , ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9) , ubiquitin-conjugating enzyme UbcE2A , ubiquitin-like protein SUMO-1 conjugating enzyme , ubiquitin-protein ligase E2I , ubiquitin-protein ligase I , Ubiquitin conjugating enzyme E2I (homologous to yeast UBC9) , SUMO-conjugating enzyme UBC9-A , SUMO-protein ligase A , ubc9.1 , ubiquitin carrier protein 9-A , ubiquitin carrier protein I-A , ubiquitin-conjugating enzyme 9 , ubiquitin-conjugating enzyme E2 I-A , ubiquitin-protein ligase I-A , ubiquitin-conjugating enzyme E2I (UBC9 homolog) , ubiquitin-conjugating enzyme E2 I , Ubiquitin carrier protein 9 , Ubiquitin carrier protein I , Ubiquitin-conjugating enzyme E2 I , Ubiquitin-protein ligase I , ubiquitin conjugating enzyme

GENE ID SPECIES
692788 Bombyx mori
100358924 Oryctolagus cuniculus
100533196 Sus scrofa
3565767 Caenorhabditis elegans
828909 Arabidopsis thaliana
7329 Homo sapiens
22196 Mus musculus
25573 Rattus norvegicus
30622 Danio rerio
380450 Xenopus laevis
374123 Gallus gallus
491332 Canis lupus familiaris
515573 Bos taurus
101843247 Mesocricetus auratus
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