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anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) Antibodies

The protein encoded by UBE2K belongs to the ubiquitin-conjugating enzyme family. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2K Proteins (19) and Ubiquitin-Conjugating Enzyme E2K Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBE2K 3093 P61086
UBE2K 53323 P61087
UBE2K 289623  
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Top anti-Ubiquitin-Conjugating Enzyme E2K Antibodies at antibodies-online.com

Showing 10 out of 107 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-UBE2K Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-UBE2K Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN184891 staining (1.5µg/ml) of Jurkat lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IF, WB HIP2 Antibody (D124) (ABIN1882088) western blot analysis in 293,mouse C2C12 cell line lysates (35 µg/lane). This demonstrates the HIP2 antibody detected the HIP2 protein (arrow). HIP2 Antibody (D124) (ABIN1882088) western blot analysis in 293,mouse C2C12 cell line lysates (35 µg/lane). This demonstrates the HIP2 antibody detected the HIP2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB UBE2K Antibody (N-term) (ABIN1881965) western blot analysis in 293,Hela,mouse C2C12 cell line and mouse brain tissue lysates (35 µg/lane). This demonstrates the UBE2K antibody detected the UBE2K protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Cow Rabbit Un-conjugated WB Figure 1. Western Blot using HIP2 antibody (at 1/1000 dilution): Sample (30 µg of whole cell lysate) A: HCT116 12% SDS PAGE 0.1 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-HIP2 Polyclonal Antibody, Unconjugated (ABIN1387369) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details

UBE2K Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-Ubiquitin-Conjugating Enzyme E2K Antibodies

  1. Human Polyclonal UBE2K Primary Antibody for WB - ABIN1881965 : Bae, Kho, Lee, Rhim, Kang: Hip2 interacts with and destabilizes Smac/DIABLO. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 5 references for ABIN1881965

  2. Human Polyclonal UBE2K Primary Antibody for IF, WB - ABIN1882088 : Furukawa, Kubo, Kikuchi, Tokura, Fujita, Sakurabayashi: Regulation of macrophage-specific gene expression by degenerated lipoproteins. in Electrophoresis 2000 (PubMed)
    Show all 4 references for ABIN1882088

  3. Chicken Polyclonal UBE2K Primary Antibody for WB - ABIN2787510 : Christensen, Brzovic, Klevit: E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages. in Nature structural & molecular biology 2007 (PubMed)
    Show all 2 references for ABIN2787510

  4. Cow (Bovine) Polyclonal UBE2K Primary Antibody for WB - ABIN374290 : Kalchman, Graham, Xia, Koide, Hodgson, Graham, Goldberg, Gietz, Pickart, Hayden: Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme. in The Journal of biological chemistry 1996 (PubMed)

More Antibodies against Ubiquitin-Conjugating Enzyme E2K Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2K (UBE2K) interaction partners

  1. The crystal structure of a Ube2K~ubiquitin conjugate has been described, and it was shown that even though it is monomeric, Ube2K can synthesize Lys48-linked ubiquitin chains.

  2. Hip2, a ubiquitin-conjugating enzyme (show Ube2t Antibodies), can overcome radiation-induced G2/M cell cycle arrest and trigger the entry into mitosis.

  3. An extract of bark from the tropical rainforest plant Byrsonima crassifolia was screened for inhibition of diubiquitin (show UBD Antibodies) formation by the human ubiquitin-conjugating enzyme E2-25K.

  4. one of the roles of the C-terminal UBA domain, in the context of E2-25K, is to increase processivity in Lys48-linked polyubiquitin (show UBB Antibodies) chain synthesis, possibly through increased binding to the ubiquitinated substrate.

  5. Results suggest that the interaction between E2-25K and UBB (show UBB Antibodies)(+1) is critical for the synthesis and accumulation of UBB (show UBB Antibodies)(+1)-anchored polyubiquitin (show UBB Antibodies), which results in proteasomal inhibition and neuronal cell death.

  6. This study suggests that Hip2 might be involved in the regulation of Smac (show DIABLO Antibodies)-mediated apoptosis.

  7. Results suggest that in permeabilized, US11-expressing cells polyubiquitination of the MHC class I heavy chain substrate can be catalyzed by E2-25K.

  8. E2-25K is involved in aggregate formation of expanded polyglutamine proteins and polyglutamine-induced cell death.

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2K (UBE2K) interaction partners

  1. E2-25K/Hip-2 is thus an essential upstream regulator of the expression and activation of caspase-12 (show CASP12 Antibodies) in endoplasmic reticulum stress-mediated Abeta (show APP Antibodies) neurotoxicity.

Ubiquitin-Conjugating Enzyme E2K (UBE2K) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with UBE2K

  • ubiquitin-conjugating enzyme E2K (ube2k) antibody
  • ubiquitin-conjugating enzyme E2K (UBE2K) antibody
  • ubiquitin-conjugating enzyme E2K (Ube2k) antibody
  • ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) (ube2kb) antibody
  • AW492011 antibody
  • D5Ertd601e antibody
  • E2-25k antibody
  • Hip2 antibody
  • Hypg antibody
  • Lig antibody
  • UBC1 antibody
  • ube2k antibody
  • zgc:103472 antibody

Protein level used designations for UBE2K

ubiquitin-conjugating enzyme E2K (UBC1 homolog) , huntingtin interacting protein 2 , ubiquitin-conjugating enzyme E2-25K , ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) , ubiquitin-conjugating enzyme E2 K , ubiquitin-conjugating enzyme E2-25 kDa , E2(25K) , HIP-2 , huntingtin-interacting protein 2 , ubiquitin carrier protein , ubiquitin-conjugating enzyme E2(25K) , ubiquitin-conjugating enzyme E2-25 KDA , ubiquitin-protein ligase

GENE ID SPECIES
448153 Xenopus (Silurana) tropicalis
461178 Pan troglodytes
699734 Macaca mulatta
3093 Homo sapiens
379982 Xenopus laevis
428787 Gallus gallus
609531 Canis lupus familiaris
281225 Bos taurus
53323 Mus musculus
289623 Rattus norvegicus
30100 Danio rerio
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