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UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. Additionally we are shipping UNC5A Proteins (7) and UNC5A Kits (1) and many more products for this protein.
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Human Polyclonal UNC5A Primary Antibody for WB - ABIN2784134
Arakawa: Netrin-1 and its receptors in tumorigenesis. in Nature reviews. Cancer 2004
FANCC (show FANCC Antibodies) interferes with UNC5A's functions in apoptosis and suggest that FANCC (show FANCC Antibodies) may participate in developmental processes through association with the dependence receptor UNC5A.
these data suggest an important role for UNC5A, a candidate tumor suppressor, in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer
UNC5A is a novel transcriptional target of p53 (show TP53 Antibodies) and plays a role in p53 (show TP53 Antibodies)-dependent apoptosis
may represent tumor suppressor that inhibit tumor extension outside the region of netrin-1 (show NTN1 Antibodies) availability by inducing apoptosis
Unc5h1 was cloned; its expression is restricted to the central nervous system in developing mouse
a mechanism for UNC5H1-mediated apoptosis that requires an interaction with the MAGE (show MAGEB10 Antibodies) protein NRAGE (show MAGED1 Antibodies)
Results suggest that UNC5A promotes neuronal apoptosis during spinal cord development independent of netrin-1 (show NTN1 Antibodies).
UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).
unc-5 homolog A (C. elegans)
, unc-5 homolog A-like
, netrin receptor UNC5A
, netrin receptor Unc5h1
, protein unc-5 homolog 1
, protein unc-5 homolog A
, unc-5 homolog 1
, unc5 (C.elegans homolog) a
, unc5 homolog 1
, transmembrane receptor Unc5H1