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USF2 encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. Additionally we are shipping Upstream Transcription Factor 2, C-Fos Interacting Antibodies (95) and Upstream Transcription Factor 2, C-Fos Interacting Kits (3) and many more products for this protein.
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Pdx1 (show PDX1 Proteins), USF1 (show USF1 Proteins) and USF2 co-ordinately regulate Alx3 (show ALX3 Proteins) gene expression in pancreatic beta-cells.
AGTRAP (show AGTRAP Proteins) expression is regulated by USF1 (show USF1 Proteins) and USF2
USF1 (show USF1 Proteins) and USF2 are important regulatory factors for Alx3 (show ALX3 Proteins) gene expression in different cell types
Data suggest that both USF1 (show USF1 Proteins) and USF2 are essential for angiotensinogen (AGT (show AGT Proteins)) transcriptional regulation, and distinct sex-specific and tissue-specific mechanisms are involved in the activities of these transcription factors.
USF-1 but not USF-2 was strongly enriched at Dbeta2 in chromatin from either Rag2-/- double-negative thymocytes or Rag2-/- thymocytes that express a rearranged Tcrb transgene.
USF binding to the E-box at -893/-888 serves to trans-repress basal expression and IL-1beta (show IL1B Proteins) induction of the iNOS (show NOS2 Proteins) promoter.
USF1 (show USF1 Proteins) and USF2 play a functional role in RANKL (show TNFSF11 Proteins)-dependent TRAP expression during osteoclast differentiation.
Blood oxytocin concentrations on d 9 postpartum were also lower in Usf2-/- mice than Usf2+/+ mice
Data show that USF1 (show USF1 Proteins)/-2 and CREB (show CREB1 Proteins) transcription factors binding to the cyclooxygenase-2 (show PTGS2 Proteins) promoter induced H. pylori-dependent cox-2 transcription.
transcription factors upstream stimulatory factor (USF) and c-Myc (show MYC Proteins) may exert opposing effects on PIGR (show PIGR Proteins) promoter activity
USF2, and its target gene PAI-1 (show SERPINE1 Proteins), regulate serum-stimulated keratinocyte growth, and likely the cadence of cell cycle progression in replicatively competent cells as part of the injury repair program.
Increased upstream stimulatory factor in HCC (show FAM126A Proteins) is associated with heparanase (show HPSE Proteins) expression. USF might be an important factor in regulating HPSE (show HPSE Proteins) expression and act as a novel marker of metastatic recurrence of HCC (show FAM126A Proteins) patients
RNA Pol II on HIF1 (show HIF1A Proteins) or HIF2 (show EPAS1 Proteins) target genes is primarily associated with HIF1alpha (show HIF1A Proteins) or HIF2alpha (show EPAS1 Proteins) in a STAT3 (show STAT3 Proteins) or USF2 dependent manner
USF2 functionally interacts with YY1 (show YY1 Proteins) blocking its inhibitory activity, in favor of CEBPB (show CEBPB Proteins) transactivation.
USF2 and hypoxia-inducible factor 2alpha (HIF2alpha (show EPAS1 Proteins)) cooperatively activate HIF2 (show EPAS1 Proteins) target genes during hypoxia.
Transcription factors upstream stimulatory factor 1 (USF-1 (show USF1 Proteins)) and USF-2 are indispensable for the transcription of RORgammaT in human lymphocytes.
Bone morphogenetic proteins and ID1 (show ID1 Proteins) exerted an anti-apoptotic effect in mesangial cells by inhibition of USF2 transcriptional activity.
These data indicate that an E-box motif (RBE1) within the core promoter in the long terminal repeat of HIV-1 is a bona fide binding site for the RBF (show ATP5I Proteins)-2 transcription factor complex USF1 (show USF1 Proteins), USF2, and TFII-I (show GTF2I Proteins).
data established that high glucose stimulated USF2 expression in HK-2 (show HK2 Proteins) cells, at least in part, through angiotensin II-AT1 (show AGTR1 Proteins)-dependent activation of CREB (show CREB1 Proteins), which can contribute to diabetic tubulointerstitial fibrosis
Usf2 mediates quercetin-induced suppression of PAI-1 (show SERPINE1 Proteins) gene expression in human endothelial cells
bovine upstream stimulatory factor 1 (show USF1 Proteins) and 2 have roles regulating the prostaglandin G/H synthase-2 (show PTGS2 Proteins) promoter in granulosa cells [USF1 (show USF1 Proteins)/USF2]
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene.
upstream transcription factor 2, c-fos interacting
, upstream stimulatory factor 2
, major late transcription factor 2
, FOS-interacting protein
, c-fos interacting protein
, class B basic helix-loop-helix protein 12
, transcription factor USF2