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UPK3A encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Additionally we are shipping Uroplakin 3A Antibodies (45) and Uroplakin 3A Kits (7) and many more products for this protein.
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High expression level of preoperative serum Uroplakin III is associated with biologically aggressive bladder cancer.
High Uroplakin III expression is associated with bladder urothelial carcinoma from malignancy metastatic to the urinary bladder.
a strong association between UPIII and in the group with tumor recurrence
Loss of p63 (show RPE65 Proteins) expression is a prerequisite for uroplakin III expression in urothelial bladder cancer.
Our results indicate that de novo mutations in UPIIIA can be involved in defective early kidney development, but probably constitute only a rare cause of human renal hypodysplasia in a minor subset of individuals [UPIIIA].
uroplakin III and III-delta4 genes were significantly up-regulated only in patients with nonulcerative interstitial cystitis
Uroplakin III mRNA is up-regulated to a greater extent in vesicoureteral reflux than in control exfoliated urinary cells.
Uroplakin III plays a pivotal role in Eshcerichia coli UTI (show AMBP Proteins) pathogenesis.
studies suggest that bacteria-induced UPIIIa signaling is a critical mediator of bladder responses to insult by uropathogenic E. coli
U-CCs (show CCS Proteins) (Uroplakin3a expressing cells )proliferate and generate CCs (show CCS Proteins) and ciliated cells in uninjured airways long-term and, like v-CCs (show CCS Proteins), after Nap (show CTNNBL1 Proteins). U-CCs (show CCS Proteins) have a higher propensity to generate ciliated cells than non-U-CCs (show CCS Proteins)
A UPK3A peptide can induce a peptide-specific CD4 (show CD4 Proteins)+ T cell autoimmunity that mediates painful bladder dysfunction in mice.
The despites a lower level of expression, UPIIIa maintain its plaque association in urothelial preneoplastic lesions.
This gene encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Mutations in this gene may be associated with renal adysplasia. Alternatively spliced transcript variants have been described.
, uroplakin 3
, uroplakin IIIA
, uroplakin III
, proplakin IIIa