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Uroporphyrinogen III Synthase Proteins (UROS)

The protein encoded by UROS catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Additionally we are shipping Uroporphyrinogen III Synthase Antibodies (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UROS 7390 P10746
UROS 22276 P51163
Rat UROS UROS 309070  
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Top Uroporphyrinogen III Synthase Proteins at antibodies-online.com

Showing 9 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Arabidopsis thaliana His tag   1 mg Log in to see 56 to 66 Days
$2,610.67
Details
Yeast Rice His tag   1 mg Log in to see 56 to 66 Days
$2,647.33
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$522.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

UROS Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced Uroporphyrinogen III Synthase Proteins

  1. Human UROS Protein expressed in Escherichia coli (E. coli) - ABIN667456 : Géronimi, Richard, Lamrissi-Garcia, Lalanne, Ged, Redonnet-Vernhet, Moreau-Gaudry, de Verneuil: Lentivirus-mediated gene transfer of uroporphyrinogen III synthase fully corrects the porphyric phenotype in human cells. in Journal of molecular medicine (Berlin, Germany) 2003 (PubMed)
    Show all 2 references for ABIN667456

More Proteins for Uroporphyrinogen III Synthase (UROS) Interaction Partners

Cow (Bovine) Uroporphyrinogen III Synthase (UROS) interaction partners

  1. Study substantiated that insufficient activity of UROS is the cause of CEP in the family studied here. and provided strong evidence for LD between markers within the region and the phenotype.

Human Uroporphyrinogen III Synthase (UROS) interaction partners

  1. REVIEW: Structural, thermodynamic, and mechanistical studies in uroporphyrinogen III synthase and molecular basis of congenital erythropoietic porphyria

  2. Intracellular rescue of the uroporphyrinogen III synthase activity in enzymes carrying the hotspot mutation C73R.

  3. Data show that branchpoint sequence (BPS)mutation reduced the wild-type transcript and UROS enzyme activity in CEP lymphoblasts to approximately 10% and 15% of normal, respectively.

  4. two novel misense mutations in the UROS gene.

  5. NMR analyses of URO-synthase titrated with competitive inhibitors N(D)-methyl-1-formylbilane or URO'gen III, revealed resonance perturbations of specific residues lining the cleft between 2 major domains of URO synthase that mapped enzyme's active site.

  6. The decrease in the expression of ubiquitous HMBS (show HMBS Proteins) and UROS mRNAs under hypoxia is associated with accumulation of hypoxia-inducible factor 1alpha protein.

  7. UROS mutations related to erythropoietic porphyria identify a key helix for protein stability.

Mouse (Murine) Uroporphyrinogen III Synthase (UROS) interaction partners

  1. Data show that in adult UROS C73R mice, spleen and liver weights were 8.2- and 1.5-fold increased, respectively.

Arabidopsis thaliana Uroporphyrinogen III Synthase (UROS) interaction partners

  1. Data show that AtDuf3 genes were expressed in roots, leaves, shoot apical meristems, anthers and pollen grains. They may form homodimers or homopolymers, but did not interact with other members of the same family.

Uroporphyrinogen III Synthase (UROS) Protein Profile

Protein Summary

The protein encoded by this gene catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunther's disease).

Gene names and symbols associated with UROS

  • uroporphyrinogen III synthase (uros)
  • uroporphyrinogen III synthase (UROS)
  • uroporphyrinogen-III synthase (UroS) (AFUA_6G12800)
  • uroporphyrinogen-iii synthase (UROS)
  • uroporphyrinogen III synthase (UroS)
  • uroporphyrinogen III synthase (Uros)
  • Uroporphyrinogen-III synthase (HEMD)
  • Afu6g12800 protein
  • AI415298 protein
  • ARABIDOPSIS THALIANA UROPORPHYRINOGEN III SYNTHASE protein
  • ATDUF3 protein
  • ATUROS protein
  • DOMAIN OF UNKNOWN FUNCTION 724 3 protein
  • DUF3 protein
  • MGC85561 protein
  • T9J22.21 protein
  • T9J22_21 protein
  • UROIIIS protein
  • UROPORPHYRINOGEN III SYNTHASE protein
  • UROS protein
  • Uros3 protein
  • wu:fd13d11 protein
  • zgc:110240 protein

Protein level used designations for UROS

uroporphyrinogen-III synthase , uroporphyrinogen III synthase (congenital erythropoietic porphyria) , hydroxymethylbilane hydrolyase, cyclizing , uroporphyrinogen-III cosynthetase , uroporphyrinogen-iii synthase , uroporphyrinogen III synthase , hydroxymethylbilane hydrolyase , uroporphyrinogen-III cosynthase , URO-synthase , UROIIIS , hydroxymethylbilane hydrolyase (cyclizing) , urogen III synthase , uroporphyrinogen III co-synthase

GENE ID SPECIES
404731 Danio rerio
426223 Gallus gallus
450813 Pan troglodytes
492116 Canis lupus familiaris
613425 Bos taurus
696043 Macaca mulatta
3508465 Aspergillus fumigatus Af293
5722253 Chlamydomonas reinhardtii
7452914 Thalassiosira pseudonana CCMP1335
100037610 Triticum aestivum
447178 Xenopus laevis
7390 Homo sapiens
22276 Mus musculus
309070 Rattus norvegicus
817195 Arabidopsis thaliana
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