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V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) Proteins (MAFB)

The protein encoded by MAFB is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. Additionally we are shipping MAFB Antibodies (44) and MAFB Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAFB 9935 Q9Y5Q3
MAFB 54264 P54842
MAFB 16658 P54841
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Top MAFB Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,830.67
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,847.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,867.33
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,867.33
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,970.00
Details

MAFB Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) Interaction Partners

Human V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) interaction partners

  1. DNMT3A (show DNMT3A Proteins) R882 mutation is associated with elevated expression of MAFB and M4/M5 immunophenotype of acute myeloid leukemia (show BCL11A Proteins) blasts.

  2. MAFB is a regulator and a marker of adipose tissue inflammation, a process that subsequently causes insulin (show INS Proteins) resistance

  3. MAFB represents a unique signature and likely important regulator of the primate islet beta-cell.

  4. The rs2902940A allele carriers in the MAFB conferred a decreased serum ApoAI level in controls and an increased risk of coronary artery disease and ischemic stroke.

  5. Gata3 (show GATA3 Proteins) interacted with Gcm2 (show GCM2 Proteins) and MafB, two known transcriptional regulators of parathyroid development, and synergistically stimulated the PTH (show PTH Proteins) promoter.

  6. MiR (show MLXIP Proteins)-223 negatively regulates the growth and migration of NPC (show NPC1 Proteins) cells via reducing MAFB expression, and this finding provides a novel insight into understanding miR (show MLXIP Proteins)-223 regulation mechanism in nasopharyngeal carcinoma tumorigenesis.

  7. rs6065259 was the most important single nucleotide polymorphism in MAFB (OR6065259-AA=0.45; 95% CI: 0.28 to 0.71; p=0.0027), followed by rs13041247; no association was found between rs11696257 and NSCLP.

  8. These findings indicate that only a few transactivation domain-specific mutations within MAFB cause multicentric carpotarsal osteolysis.

  9. Mafb is responsible for executing one branch of the SGN differentiation program orchestrated by the Gata3 (show GATA3 Proteins) transcriptional network

  10. MAFA (show KLRG1 Proteins), MAFB, NKX6.1 (show NKX6-1 Proteins), and PDX1 (show PDX1 Proteins) activity provides a gauge of islet beta cell function, with loss of MAFA (show KLRG1 Proteins) (and/or MAFB) representing an early indicator of beta cell inactivity

Zebrafish V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) interaction partners

  1. Vegfc (show VEGFC Proteins) signaling increases mafba expression to control downstream transcription

Mouse (Murine) V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) interaction partners

  1. MafB and c-Maf (show MAF Proteins) have different expression patterns in macrophages, suggesting differences in function.

  2. MAFB is an important transcription factor involved in lymphangiogenesis.

  3. Study provides insights to elucidate mechanisms of gene regulation through androgen response elements present in Mafb 3'UTR for a better understanding of the processes of urethral masculinization.

  4. It contributes to the development of hyperglycemia in the Mafa (show MAFA Proteins)-deficient background in adults as well as in embryos.

  5. MafB is only essential to islet alpha-cell activity and not beta-cell.

  6. findings represent the first evidence that the macrophage-affiliated MafB transcription factor participates in the acceleration of atherogenesis

  7. Data, including data from studies using transgenic/knockout mice, confirm the expression of Mafa (show MAFA Proteins) and Mafb is specific to insulin (show INS Proteins)-secreting cells of the pancreas.

  8. Mafb-deficient microglia cultured with GM-CSF (show CSF2 Proteins) barely extended their membrane protrusions, probably due to abnormal activation of RhoA (show RHOA Proteins), a key regulator of cytoskeletal remodeling. MafB is a negative regulator of GM-CSF (show CSF2 Proteins) signaling in microglia.

  9. high-resolution structures of the transcription factor MafB as a homodimer and as a heterodimer with c-Fos bound to variants of the Maf (show MAF Proteins)-recognition element

  10. Mafb is expressed in male genital tubercle (GT) mesenchyme. Exogenous androgen induces its mesenchymal expression in female GTs. AR signaling is necessary for its expression. Mafb KO male GTs have defective embryonic urethral formation.

MAFB Protein Profile

Protein Summary

The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns.

Gene names and symbols associated with MAFB

  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) (MAFB)
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (mafb)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B (mafb)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B (MAFB)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B (Mafb)
  • v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (mafba)
  • v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb)
  • b-maf protein
  • kr protein
  • Kreisler protein
  • Krml protein
  • Krml1 protein
  • Maf-B protein
  • mafb protein
  • MCTO protein
  • MGC108453 protein
  • val protein
  • valentino protein
  • wu:fc22d11 protein
  • wu:fj82a09 protein
  • XMafB protein

Protein level used designations for MAFB

v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) , v-maf musculoaponeurotic fibrosarcoma oncogene protein B , v-maf musculoaponeurotic fibrosarcoma oncogene homolog B , Transcription factor MafB , bzip transcription factor mafB , transcription factor MafB , Kreisler maf-related leucine zipper homolog , MAFB/Kreisler basic region/leucine zipper transcription factor , Kreisler maf-related leucine zipper homolog (b-maf) , maf-B , transcription factor Maf-1 , v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B , transcription factor Val , valentino , Kreisler (maf-related) leucine zipper protein , V-maf musculoaponeurotic fibrosarcoma oncogene homolog B , segmentation protein Kr

GENE ID SPECIES
469941 Pan troglodytes
554333 Ovis aries
595086 Xenopus (Silurana) tropicalis
399156 Xenopus laevis
9935 Homo sapiens
532376 Bos taurus
54264 Rattus norvegicus
30210 Danio rerio
16658 Mus musculus
419173 Gallus gallus
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