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ETS1 encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. Additionally we are shipping V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) Kits (14) and V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) Proteins (10) and many more products for this protein.
Showing 10 out of 189 products:
Human Polyclonal ETS1 Primary Antibody for EIA, FACS - ABIN952130
Harris, Yamakuchi, Kondo, Oettgen, Lowenstein: Ets-1 and Ets-2 regulate the expression of microRNA-126 in endothelial cells. in Arteriosclerosis, thrombosis, and vascular biology 2010
Show all 4 references for 952130
Human Monoclonal ETS1 Primary Antibody for IHC, ELISA - ABIN1724736
Chen, Shin, Lin: Ets1 was significantly activated by ERK1/2 in mutant K-ras stably transfected human adrenocortical cells. in DNA and cell biology 2005
Show all 2 references for 1724736
Human Monoclonal ETS1 Primary Antibody for ICC, FACS - ABIN1724735
Kessler, Schroeder, Brar, Handwerger: Transcription factor ETS1 is critical for human uterine decidualization. in Molecular human reproduction 2006
Show all 2 references for 1724735
Cow (Bovine) Polyclonal ETS1 Primary Antibody for IHC, WB - ABIN2792530
Yordy, Li, Sementchenko, Pei, Muise-Helmericks, Watson: SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion. in Oncogene 2004
Human Polyclonal ETS1 Primary Antibody for IF, IHC - ABIN1532334
Gao, Peng, Liang, Shahbaz, Liu, Wang, Sun, Niu, Niu, Liu, Wang, Lin, Wang, Niu: β6 integrin induces the expression of metalloproteinase-3 and metalloproteinase-9 in colon cancer cells via ERK-ETS1 pathway. in Cancer letters 2014
Human Monoclonal ETS1 Primary Antibody for ELISA, IHC - ABIN4309665
Meerson, Traurig, Ossowski, Fleming, Mullins, Baier: Human adipose microRNA-221 is upregulated in obesity and affects fat metabolism downstream of leptin and TNF-α. in Diabetologia 2013
Dynamically and epigenetically coordinated GATA2 (show GATA2 Antibodies)/ETS1SOX7 transcription factor expression is indispensable for endothelial cell differentiation.
data reveal ETS1 as a critical regulator of ILC2 expansion and cytokine production and implicate ETS1 in the regulation of Id2 at the inception of ILC2 development.
Ets1 predominantly binds distal nucleosome-occupied regions in double negative thymocytes and nucleosome-depleted regions in double positive thymocytes. importantly, Ets1 induces chromatin remodeling by displacing H3K4me1-marked nucleosomes.
reduced lung levels of PPARgamma (show PPARG Antibodies) and increased levels of microRNA-27a (miR (show MLXIP Antibodies)-27a), v-ets avian erythroblastosis virus E26 oncogene (show RAB1A Antibodies) homolog 1 (ETS1), endothelin-1 (ET-1 (show EDN1 Antibodies)), and markers of endothelial dysfunction (platelet/endothelial cell adhesion molecule 1 (show PECAM1 Antibodies) and E selectin (show SELE Antibodies)).
the affinities of two sequence-divergent ETS homologs, PU.1 and Ets-1, to DNA sites harboring a hemi- and fully methylated CpG dinucleotide, were measured.
data support a general model in which Ets-1 interacts with nonspecific DNA via dynamic electrostatic interactions, whereas hydrogen bonding drives the formation of well-ordered complexes with specific DNA
Ets-1 links glucotoxicity to pancreatic beta cell dysfunction through inhibiting PDX-1 (show PDX1 Antibodies) expression in type 2 diabetes.
Akt2 (show AKT2 Antibodies) upregulates dendritic cell migration at least in part by ETS1-dependent stimulation of IP3R2 (show ITPR2 Antibodies) transcription.
The short nose, otitis media, and hearing impairment in Jacobsen syndrome are likely because of hemizygosity for ETS1 and FLI1 (show FLI1 Antibodies).
Ets1 and Sox10 (show SOX10 Antibodies) interact to promote proper melanocyte and enteric ganglia development from the neural crest.
ZEB1 (show ZEB1 Antibodies) upregulation by SPRY2 (show SPRY2 Antibodies) results from the combined induction of ETS1 transcription factor and the repression of microRNAs (miR (show MLXIP Antibodies)-200 family, miR (show MLXIP Antibodies)-150) that target ZEB1 (show ZEB1 Antibodies) RNA. Moreover, SPRY2 (show SPRY2 Antibodies) increased AKT (show AKT1 Antibodies) activation by epidermal growth factor (show EGF Antibodies), whereas AKT (show AKT1 Antibodies) and also Src (show SRC Antibodies) inhibition reduced the induction of ZEB1 (show ZEB1 Antibodies).
Ets1 induces ZEB (show ZEB1 Antibodies) expression and activates the ZEB1 (show ZEB1 Antibodies) promoter.
Interaction with ZMYND11 (show ZMYND11 Antibodies) mediates opposing roles of Ras-responsive ETS1 and ETS2 (show ETS2 Antibodies).
a novel mechanism of miR (show MLXIP Antibodies)-29b regulation by MAPK (show MAPK1 Antibodies)-driven ETS1 expression which leads to downstream changes in TET1 (show TET1 Antibodies)-mediated epigenetic modifications.
Lipopolysaccharides-induced CDKN2A (show CDKN2A Antibodies) expression coincided with a 4.5-fold increase in ETS1 (ETS proto-oncogene (show RAB1A Antibodies) 1) mRNA, suggesting that ETS1 is involved in regulating CDKN2A (show CDKN2A Antibodies) This idea was confirmed by RNAi-mediated suppression or genetic deletion of ETS1, which blocked CDKN2A (show CDKN2A Antibodies) expression and reduced cholangiocyte senescence.
Ets-1 p27 (show PAK2 Antibodies) isoform is cleaved in the same manner as Ets-1 p51 (show ZNF398 Antibodies) isoform within the exon VII (show TH Antibodies)-encoded region, thus generating a stable C-terminal fragment that induces cell death by initiating apoptosis.
Our results indicated that ETS1 induced autophagy after inhibition of glycolysis, and thus led to comparative decrease of cell viability. These results implied that ETS1 could be a potential target for tumor metabolic therapy.
Furthermore, mir106a transfection resulted in decreased expression of MMP-2 (show MMP2 Antibodies) and diminished binding activity of transcription factor Ets (show ETV7 Antibodies)-1 in EJ cells.
Integrin b6 markedly promoted the proliferation and invasion of pancreatic carcinoma cells and induced ETS1 phosphorylation in an ERK (show EPHB2 PLURAL_@27060@)-dependent manner, leading to the upregulation of matrix metalloprotease (show ADAM8 PLURAL_@27060@)-9, which is essential for b6-mediated invasiveness of pancreatic carcinoma cells
The activity of Gata4 (show GATA4 Antibodies) cardiac enhancer in transgenic embryos and in cultured aortic endothelial cells is dependent on four ETS sites.
Ets-1 up-regulation is involved in the development of retinal neovascularization.
This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
v-ets erythroblastosis virus E26 oncogene homolog 1
, Ets protein
, v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
, protein c-ets-1-B
, C-ets-1 protein (p54)
, avian erythroblastosis virus E26 oncogene 1
, protein C-ets-1
, tumor progression locus 1
, ELK channel 3
, ether-a-go-go-like potassium channel 1
, ether-a-go-go-like potassium channel 3
, potassium voltage-gated channel subfamily H member 8
, potassium voltage-gated channel, subfamily H, member 8
, voltage-gated potassium channel subunit Kv12.1
, Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1
, ets protein
, v-ets avian erythroblastosis virus E2 oncogene homolog 1
, Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1)
, TNFAIP3 interacting protein 1
, c-ets-1 oncogene
, p54 transcription factor
, transforming protein p54/c-ets-1
, transforming protein p68/c-ets-1
, virion-associated nuclear-shuttling protein
, v-ets erythroblastosis virus E26 oncogene-like protein 1