V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) Proteins (MAFB)

The protein encoded by MAFB is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. Additionally we are shipping MAFB Antibodies (44) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAFB 9935 Q9Y5Q3
MAFB 54264 P54842
MAFB 16658 P54841
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Top MAFB Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
$2,830.67
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
$2,847.17
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 60 to 71 Days
$2,867.33
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,867.33
Details
Yeast Zebrafish His tag   1 mg Log in to see 60 to 71 Days
$2,970.00
Details

MAFB Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) Interaction Partners

Human V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) interaction partners

  1. these results demonstrate that MAFB critically determines the acquisition of the anti-inflammatory transcriptional and functional profiles of human macrophages

  2. The present study demonstrated that miR (show MLXIP Proteins)-152 was downregulated in NPC (show NPC1 Proteins) tissues and cell lines. In addition, miR (show MLXIP Proteins)-152 expression and MAFB knockdown inhibited cell proliferation, migration and invasion, and miR (show MLXIP Proteins)-152 suppressed the expression of MAFB at the mRNA and protein levels.

  3. Epidermal differentiation gene regulatory networks are controlled by MAF (show MAF Proteins) and MAFB.

  4. Loss of MAFB Function Causes Duane Syndrome, Aberrant Extraocular Muscle Innervation, and Inner-Ear Defects.

  5. Results indicate a hepatocellular carcinoma (HCC (show FAM126A Proteins)) regulatory pathway involving MafB transcription factor and cyclin D1 (show CCND1 Proteins), the dysfunction of which drives proliferative character in HCC (show FAM126A Proteins).

  6. DNMT3A (show DNMT3A Proteins) R882 mutation is associated with elevated expression of MAFB and M4/M5 immunophenotype of acute myeloid leukemia (show BCL11A Proteins) blasts.

  7. MAFB is a regulator and a marker of adipose tissue inflammation, a process that subsequently causes insulin (show INS Proteins) resistance

  8. MAFB represents a unique signature and likely important regulator of the primate islet beta-cell.

  9. The rs2902940A allele carriers in the MAFB conferred a decreased serum ApoAI level in controls and an increased risk of coronary artery disease and ischemic stroke.

  10. Gata3 (show GATA3 Proteins) interacted with Gcm2 (show GCM2 Proteins) and MafB, two known transcriptional regulators of parathyroid development, and synergistically stimulated the PTH (show PTH Proteins) promoter.

Zebrafish V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) interaction partners

  1. Vegfc (show VEGFC Proteins) signaling increases mafba expression to control downstream transcription

Mouse (Murine) V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) interaction partners

  1. Increased mafB at the common myeloid progenitor stage steers their lineage away from the megakaryocyte erythrocyte progenitor production and drives the terminal fate of these progenitors to form macrophages vs. dendritic cells, causing anemia, monocytosis, and dendritic cell loss. It is a transcriptional activator of M-CSFR (show CSF1R Proteins) and a repressor of transferrin (show Tf Proteins) receptors, promoting macrophages and plasmacytoid dendritic cells.

  2. An elevation of MSR1 (show MSR1 Proteins) levels in infiltrating myeloid cells observed 3 d after experimental stroke was dependent on the transcription factor Mafb. Mafb deficiency in infiltrating myeloid cells caused impaired clearance of DAMPs, more severe inflammation, and exacerbated neuronal injury in a murine model of ischemic stroke.

  3. a Mafb-driven Cre strain was generated to determine whether any dendritic cells (DCs) identified by Zbtb46 (show ZNF340 Proteins)-green fluorescent protein expression originate from a Mafb-expressing population.

  4. MafB deletion in maternal beta-cells also produced GDM, with inadequate beta-cell expansion accompanied by failure to induce PRLR (show PRLR Proteins)-dependent target genes regulating beta-cell proliferation. These results unveil molecular roles for PRLR (show PRLR Proteins) signaling in orchestrating the physiologic expansion of maternal beta-cells during pregnancy.

  5. MafB play an important role in promoting hindbrain choroid plexus development during embryogenesis

  6. Meanwhile, the observed reduction in the phagocytic activity of the MafB-shRNA-expressing cells was attenuated by ectopic expression of Fcgr3. Together, the results presented here indicate that MafB influences the phagocytic activity of macrophages by promoting Fcgr3, but not Fcgr2b, expression.

  7. Loss of MAFB Function Causes Duane Syndrome, Aberrant Extraocular Muscle Innervation, and Inner-Ear Defects.

  8. MafB and c-Maf (show MAF Proteins) have different expression patterns in macrophages, suggesting differences in function.

  9. MAFB is an important transcription factor involved in lymphangiogenesis.

  10. Study provides insights to elucidate mechanisms of gene regulation through androgen response elements present in Mafb 3'UTR for a better understanding of the processes of urethral masculinization.

MAFB Protein Profile

Protein Summary

The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns.

Gene names and symbols associated with MAFB

  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) (MAFB)
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (mafb)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B (mafb)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B (MAFB)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B (Mafb)
  • v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (mafba)
  • v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb)
  • b-maf protein
  • kr protein
  • Kreisler protein
  • Krml protein
  • Krml1 protein
  • Maf-B protein
  • mafb protein
  • MCTO protein
  • MGC108453 protein
  • val protein
  • valentino protein
  • wu:fc22d11 protein
  • wu:fj82a09 protein
  • XMafB protein

Protein level used designations for MAFB

v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) , v-maf musculoaponeurotic fibrosarcoma oncogene protein B , v-maf musculoaponeurotic fibrosarcoma oncogene homolog B , Transcription factor MafB , bzip transcription factor mafB , transcription factor MafB , Kreisler maf-related leucine zipper homolog , MAFB/Kreisler basic region/leucine zipper transcription factor , Kreisler maf-related leucine zipper homolog (b-maf) , maf-B , transcription factor Maf-1 , v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B , transcription factor Val , valentino , Kreisler (maf-related) leucine zipper protein , V-maf musculoaponeurotic fibrosarcoma oncogene homolog B , segmentation protein Kr

GENE ID SPECIES
469941 Pan troglodytes
554333 Ovis aries
595086 Xenopus (Silurana) tropicalis
399156 Xenopus laevis
9935 Homo sapiens
532376 Bos taurus
54264 Rattus norvegicus
30210 Danio rerio
16658 Mus musculus
419173 Gallus gallus
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