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VCX2 belongs to the VCX\\/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells.
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This gene belongs to the VCX\\/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number\\\\; different individuals may have a different number of VCX genes. VCX\\/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX\\/Y members are nuclear proteins. This gene contains 2 repeats of the 30-bp unit.
, variable charge X-linked protein 2
, variable charge protein on X with two repeats
, variably charged X-B
, variably charged protein X-B