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anti-Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2) Antibodies

The protein encoded by VAMP2 is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Additionally we are shipping VAMP2 Proteins (12) and VAMP2 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
VAMP2 22318 P63044
VAMP2 24803 P63045
VAMP2 6844 P63027
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Top anti-VAMP2 Antibodies at antibodies-online.com

Showing 10 out of 99 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μL Log in to see 6 to 8 Days
$308.00
Details
Human Guinea Pig Un-conjugated ICC, IP, IHC, WB dilution: 1 : 1000, sample: crude synaptosomal fraction of rat brain (P2) Immunocytochemistry on cultured hippocampus neurons (dilution 1 : 1000) 100 μL Log in to see 5 to 6 Days
$358.05
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Human Testis (formalin-fixed, paraffin-embedded) stained with VAMP2 antibody ABIN364330 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with VAMP2 antibody ABIN364330 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, WB IF on 1 day- old mouse cortical cell culture using Rabbit antibody to Vesicle-associated membrane protein 2 (VAMP-2, Synaptobrevin-2, VAMP2, SYB2): whole serum (ABIN351357) at 1: 2000 dilution. DAPI counter stained. WB on rat brain lysate using Rabbit antibody to Vesicle-associated membrane protein 2 (VAMP-2, Synaptobrevin-2, VAMP2, SYB2): whole serum (ABIN351357) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide abolishes the detected band. 100 μL Log in to see 7 to 8 Days
$454.67
Details
Human Mouse Un-conjugated IHC, ELISA, WB 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Mouse Un-conjugated ELISA, WB The recombinant Synaptobrevin 1,2(each 20ng) and the extracts of Rat brain(20 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human Synaptobrevin 2 (1:2,000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 100 μL Log in to see 3 to 4 Days
$376.79
Details
Rat Mouse Un-conjugated ICC, ELISA, WB 100 μg Log in to see 5 to 6 Days
$464.80
Details
Rat Mouse Un-conjugated ICC, ELISA 25 μg Log in to see 5 to 6 Days
$485.80
Details
Rat Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$507.83
Details

VAMP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-VAMP2 Antibodies

  1. Human Polyclonal VAMP2 Primary Antibody for IHC, WB - ABIN351357 : Archer, Ozçelik, Jahn, Francke, Südhof: Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2. in The Journal of biological chemistry 1990 (PubMed)
    Show all 7 references for ABIN351357

  2. Human Polyclonal VAMP2 Primary Antibody for ICC, IP - ABIN1742194 : Kung, Gong, Adedoyin, Ng, Bhargava, Ohara, Jasmin: Evidence for glutamate as a neuroglial transmitter within sensory ganglia. in PLoS ONE 2013 (PubMed)
    Show all 2 references for ABIN1742194

  3. Human Monoclonal VAMP2 Primary Antibody for EIA, IHC (p) - ABIN317061 : Pennuto, Bonanomi, Benfenati, Valtorta: Synaptophysin I controls the targeting of VAMP2/synaptobrevin II to synaptic vesicles. in Molecular biology of the cell 2003 (PubMed)

More Antibodies against VAMP2 Interaction Partners

Zebrafish Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2) interaction partners

  1. findings reveal a novel signalling pathway involved in development of the semicircular canal system, and suggest a previously unrecognized role for NCS-1 (show NCS1 Antibodies) in mitochondrial function via its association with several mitochondrial proteins.

Mouse (Murine) Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2) interaction partners

  1. The balance between synaptophysin (show SYP Antibodies) and sybII levels is critical for the correct targeting of sybII to synaptic vesicles and suggests that alterations in synaptophysin (show SYP Antibodies) levels might affect the localisation of sybII and subsequent presynaptic performance.

  2. Thus, lipid-anchored syb2 provides little or no support for exocytosis, and anchoring syb2 to a membrane by a TMD (show TTN Antibodies) greatly improves its function

  3. Vamp2 mutations impair the ability of Munc18-1 (show STXBP1 Antibodies) to promote trans-SNARE (show VTI1B Antibodies) zippering. These mutations inhibit spontaneous as well as evoked neurotransmitter release, providing evidence for the Vamp2-regulating function of Munc18-1 (show STXBP1 Antibodies) in synaptic exocytosis.

  4. These results provide a novel molecular mechanism for autocrine negative feedback regulation of insulin (show INS Antibodies) secretion.

  5. Results suggest that side chains in the syb2 transmembrane domain influence the kinetics of exocytosis by perturbing the packing of the surrounding lipids

  6. we demonstrate that Syb2 and SNAP25 (show SNAP25 Antibodies) mediate the vesicular release of BDNF (show BDNF Antibodies) in axons and dendrites of cortical neurons

  7. Here we report on transgenic mice expressing a ubiquitinated synaptic vesicle protein (Ub(G76V)-GFP-Syb2) that develop progressive degeneration of motor nerve terminals.

  8. VAMP2 is the major v-SNARE (show GOSR1 Antibodies) involved in GLUT4 (show SLC2A4 Antibodies) trafficking to the surface of 3T3-L1 adipocytes.

  9. These results indicate a role for the syb2 TMD in nascent fusion pores, but in a very different structural arrangement from that of the syntaxin transmembrane domains.

  10. Data show a significant increase of vesicle-associated membrane protein 2 (VAMP-2) mRNA expression, however, the expressions of synaptosome-associated protein of 25 kDa (SNAP-25 (show SNAP25 Antibodies)) and syntaxin 1A (show STX1A Antibodies) did not exhibit the changes in hippocampus.

Human Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2) interaction partners

  1. This study showed that decreased Levels of VAMP2 correlate with Duration of Dementia.

  2. VAMP2-NRG1 (show NRG1 Antibodies) is a novel oncogenic fusion gene representing a new addition to the list of NRG1 (show NRG1 Antibodies) fusion genes, which together may form an important diagnostic and clinical category of lung adenocarcinoma cases

  3. A large vesicular pool of VAMP2 maintained by AP180 (show SNAP91 Antibodies) is crucial to sustain efficient neurotransmission.

  4. SNARE (show NAPA Antibodies) complex genes and their interactions may play a significant role in susceptibility and working memory of ADHD.

  5. miR (show MLXIP Antibodies)-206 regulates lung surfactant secretion by limiting the availability of VAMP-2 protein.

  6. The genetic variations of VAMP2, Synaptotagmin XI (show SYT11 Antibodies) might be indication of the relationship between these genes and idiopathic generalized epilepsy

  7. BoNT/F5 cleaves substrate synaptobrevin-2 in a different location than the other BoNT/F subtypes, between (54)L and (55)E.

  8. unique mechanism of SNARE (show NAPA Antibodies) motif-dependent endocytic sorting and identify the ANTH domain proteins AP180 (show SNAP91 Antibodies) and CALM as cargo-specific adaptors for synaptobrevin 2 endocytosis

  9. VAMP2 mediates the trafficking of alpha5beta1 integrin to the plasma membrane and VAMP2-dependent integrin trafficking is critical in cell adhesion, migration and survival.

  10. SNAP-23 (show SNAP23 Antibodies) and syntaxin-4 (show STX4 Antibodies) are expressed in human eosinophils and are likely candidates for association with VAMP-2 during docking, which is followed by exocytosis

Cow (Bovine) Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2) interaction partners

  1. VAMP-2 is critical to lysosome fusion in membrane raft clustering, and this VAMP-2-mediated lysosome-MR signalosomes contribute to redox regulation of coronary endothelial function.

  2. VAMP2 is restricted from forming the SNARE (show NAPA Antibodies) (soluble N-ethylmaleimide-sensitive fusion protein (show NSF Antibodies) attachment protein receptor) complex in chromaffin granules from adrenal medullae to the same degree as in brain-purified synaptic vesicles.

  3. Lengthening juxtamembrane region of synaptobrevin-2 severely reduced occurrence of rapid single events, leaving slow ones unchanged. It also impaired increase in fast-fusion mode that normally follows elevation of intracellular Ca2 (show CA2 Antibodies)+ levels.

VAMP2 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.

Gene names and symbols associated with VAMP2

  • vesicle-associated membrane protein 2 (vamp2) antibody
  • vesicle-associated membrane protein 2 (synaptobrevin 2) (VAMP2) antibody
  • vesicle-associated membrane protein 2 (synaptobrevin 2) (vamp2-a) antibody
  • vesicle-associated membrane protein 2 (synaptobrevin 2) (LOC100232098) antibody
  • vesicle-associated membrane protein 2 (Vamp2) antibody
  • vesicle-associated membrane protein 2 (synaptobrevin 2) (Vamp2) antibody
  • vesicle-associated membrane protein 2 (synaptobrevin 2) (vamp2-b) antibody
  • RATVAMPB antibody
  • RATVAMPIR antibody
  • SYB antibody
  • Syb-2 antibody
  • syb2 antibody
  • sybII antibody
  • VAMP-2 antibody
  • vamp2 antibody
  • vamp2-a antibody
  • wu:fj61c06 antibody
  • xsybi antibody
  • xsybii antibody
  • zgc:73302 antibody

Protein level used designations for VAMP2

vesicle-associated membrane protein 2 (synaptobrevin 2) , VAMP-2 , synaptobrevin II , synaptobrevin-2 , vesicle-associated membrane 2 , Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2) , Vesicle-associated membrane protein (synaptobrevin 2) , synaptobrevin 2 , vesicle associated membrane protein 2 , vesicle-associated membrane protein 2 , SYBII

GENE ID SPECIES
336281 Danio rerio
747237 Pan troglodytes
394286 Xenopus laevis
100232098 Taeniopygia guttata
22318 Mus musculus
24803 Rattus norvegicus
6844 Homo sapiens
282116 Bos taurus
424827 Gallus gallus
479491 Canis lupus familiaris
100732271 Cavia porcellus
394287 Xenopus laevis
574134 Macaca mulatta
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