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VAMP2 Products

(Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2))
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008].

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Featured VAMP2 Categories

VAMP2 Antibodies

High quality antibodies with extensive validation data.

VAMP2 ELISA Kits

Reliable ELISA kits for a wide range of species.

VAMP2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended VAMP2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN1513674
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN364330
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN7271313
Quantity 100 μL
Datasheet Datasheet

Recommended VAMP2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960482
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385695
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4885011
Quantity 96 tests
Datasheet Datasheet

Recommended VAMP2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125711
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125710
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5569737
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our VAMP2 products

Mañucat-Tan, Shen, Bobrovskaya, Al-Hawwas, Zhou, Wang, Zhou: "Knockout of p75 neurotrophin receptor attenuates the hyperphosphorylation of Tau in pR5 mouse model." in: Aging, Vol. 11, Issue 17, pp. 6762-6791, (2020) (PubMed).

van Stegen, Dagar, Gottmann: "Release activity-dependent control of vesicle endocytosis by the synaptic adhesion molecule N-cadherin." in: Scientific reports, Vol. 7, pp. 40865, (2017) (PubMed).

Schaefer, Toral, Velez, Cox, Baker, Borcherding, Colgan, Bondada, Mashburn, Yu, Geddes, Tsang, Bassuk, Mahajan: "Calpain-5 Expression in the Retina Localizes to Photoreceptor Synapses." in: Investigative ophthalmology & visual science, Vol. 57, Issue 6, pp. 2509-21, (2016) (PubMed).

Kung, Gong, Adedoyin, Ng, Bhargava, Ohara, Jasmin: "Evidence for glutamate as a neuroglial transmitter within sensory ganglia." in: PLoS ONE, Vol. 8, Issue 7, pp. e68312, (2013) (PubMed).

Kong, Wong, Chan, Lo: "Chronic exposure of adult rats to low doses of methylmercury induced a state of metabolic deficit in the somatosensory cortex." in: Journal of proteome research, Vol. 12, Issue 11, pp. 5233-45, (2013) (PubMed).

Zhang, Wang, Sun, Xu, Chiang, Shin, Wu: "The SNARE proteins SNAP25 and synaptobrevin are involved in endocytosis at hippocampal synapses." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 21, pp. 9169-75, (2013) (PubMed).

Usami, Hatano, Imai, Kubo, Sato, Saiki, Fujioka, Ohba, Sato, Funayama, Eguchi, Shiba, Ariga, Shen, Hattori: "DJ-1 associates with synaptic membranes." in: Neurobiology of disease, Vol. 43, Issue 3, pp. 651-62, (2011) (PubMed).

Fields, Shteyn, Pypaert, Proux-Gillardeaux, Kang, Galli, Fölsch: "v-SNARE cellubrevin is required for basolateral sorting of AP-1B-dependent cargo in polarized epithelial cells." in: The Journal of cell biology, Vol. 177, Issue 3, pp. 477-88, (2007) (PubMed).

Rosado, Redondo, Salido, Sage, Pariente: "Cleavage of SNAP-25 and VAMP-2 impairs store-operated Ca2+ entry in mouse pancreatic acinar cells." in: American journal of physiology. Cell physiology, Vol. 288, Issue 1, pp. C214-21, (2004) (PubMed).

Marshall, Hitman, Partridge, Clark, Ma, Shearer, Turner: "Evidence that an isoform of calpain-10 is a regulator of exocytosis in pancreatic beta-cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 19, Issue 1, pp. 213-24, (2004) (PubMed).

Synonyms and alternative names related to VAMP2

vesicle-associated membrane protein 2 (vamp2), vesicle associated membrane protein 2 (VAMP2), vesicle associated membrane protein 2 S homeolog (vamp2.S), vesicle-associated membrane protein 2 (Vamp2), vesicle-associated membrane protein 2 (synaptobrevin 2) (VAMP2), vesicle associated membrane protein 2 (Vamp2), vesicle associated membrane protein 2 L homeolog (vamp2.L), RATVAMPB, RATVAMPIR, SYB, Syb-2, Syb2, SYB2, syb2, sybII, VAMP-2, VAMP2, vamp2, vamp2-a, wu:fj61c06, xsybi, xsybii, zgc:73302

Protein level used designations for VAMP2

  • vesicle-associated membrane protein 2 (synaptobrevin 2)
  • VAMP-2
  • synaptobrevin II
  • synaptobrevin-2
  • vesicle-associated membrane 2
  • Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2)
  • Vesicle-associated membrane protein (synaptobrevin 2)
  • synaptobrevin 2
  • vesicle associated membrane protein 2
  • vesicle-associated membrane protein 2
  • SYBII
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