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anti-WD Repeat Domain 5 (WDR5) Antibodies

WDR5 encodes a member of the WD repeat protein family. Additionally we are shipping WDR5 Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
WDR5 11091 P61964
WDR5 140858 P61965
WDR5 362093 Q498M4
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Top anti-WDR5 Antibodies at antibodies-online.com

Showing 10 out of 91 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB WDR5 Antibody (N-term) western blot analysis in A2058 cell line lysates (35 µg/lane). This demonstrates the WDR5 antibody detected the WDR5 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemistry of WDR5 in 293 cells with WDR5 antibody at 5 ug/mL. Western blot analysis of WDR5 in 293 cell lysate with WDR5 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to WDR5 on HeLa cell (antibody concentration 10 µg/mL). WDR5 monoclonal antibody (M01), clone 2C2. Western Blot analysis of WDR5 expression in A-549. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using WDR5 mouse mAb against Hela (1) cell lysate. 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated IP, IHC, WB WB Suggested Anti-WDR5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 721_B cell lysate WB Suggested Anti-WDR5  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control:.21_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated WB WDR5 Antibody (N-term)  western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the WDR5 antibody detected the WDR5 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated ELISA, WB 50 μL Log in to see 2 to 3 Days
$220.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Wdr5 AntibodyTitration: 1.0 µg/mL  Positive Control: Mouse Pancreas 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details

WDR5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Mouse (Murine)
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Rat (Rattus)



Top referenced anti-WDR5 Antibodies

  1. Human Monoclonal WDR5 Primary Antibody for IF, WB - ABIN395423 : Davis, Butcher, Docherty, Meaburn, Curtis, Simpson, Schalkwyk, Plomin: A three-stage genome-wide association study of general cognitive ability: hunting the small effects. in Behavior genetics 2010 (PubMed)
    Show all 5 references for ABIN395423

  2. Human Polyclonal WDR5 Primary Antibody for EIA, WB - ABIN493562 : Schuetz, Allali-Hassani, Martín, Loppnau, Vedadi, Bochkarev, Plotnikov, Arrowsmith, Min: Structural basis for molecular recognition and presentation of histone H3 by WDR5. in The EMBO journal 2006 (PubMed)
    Show all 4 references for ABIN493562

  3. Human Polyclonal WDR5 Primary Antibody for EIA, WB - ABIN955558 : Yates, Menon, Thompson, Bochar: Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8. in FEBS letters 2010 (PubMed)
    Show all 3 references for ABIN955558

  4. Human Monoclonal WDR5 Primary Antibody for ELISA, WB - ABIN969456 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in 2007 (PubMed)
    Show all 2 references for ABIN969456

  5. Human Monoclonal WDR5 Primary Antibody for EIA, WB - ABIN1109506 : Patel, Vought, Dharmarajan, Cosgrove: A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex. in The Journal of biological chemistry 2008 (PubMed)

  6. Human Polyclonal WDR5 Primary Antibody for EIA, IF - ABIN1449935 : Smith, Gaitatzes, Saxena, Neer: The WD repeat: a common architecture for diverse functions. in Trends in biochemical sciences 1999 (PubMed)

More Antibodies against WDR5 Interaction Partners

Xenopus laevis WD Repeat Domain 5 (WDR5) interaction partners

  1. The WDR5 is essential for vertebrate development, in that WDR5-depleted X. laevis tadpoles exhibit a variety of developmental defects and abnormal spatial Hox (show MSH2 Antibodies) gene expression.

Human WD Repeat Domain 5 (WDR5) interaction partners

  1. WDR5 over-expression is associated with poor breast cancer clinical outcome.

  2. Results identify WDR5 as a key cofactor for N-Myc (show MYCN Antibodies)-regulated transcriptional activation and tumorigenesis and as a novel therapeutic target for MYCN (show MYCN Antibodies)-amplified neuroblastomas.

  3. BIG3 may block the KPNAs (KPNA1 (show KPNA1 Antibodies), KPNA5 (show KPNA5 Antibodies), and KPNA6 (show KPNA6 Antibodies)) binding region(s) of PHB2 (show PHB2 Antibodies).

  4. solution structures of the MLL3 core complex assembled with and without WDR5 by small angle x-ray scattering show similar overall topologies

  5. Target gene recognition by MYC (show MYC Antibodies) depends on its interaction with WDR5. This interaction could create an avidity-based chromatin recognition mechanism allowing MYC (show MYC Antibodies) to select its target genes in response to both genetic and epigenetic determinants. Review.

  6. we have discovered that WDR5 plays an important role in bladder cancer suggesting that WDR5 is a potential biomarker and a promising target in the treatment of bladder cancer.

  7. Wdr5-MLL (show MLL Antibodies) interaction in C/EBPA (show CEBPA Antibodies) N-terminal leukemia is a promising pharmacological target.

  8. findings prove that the TSP-1 (show THBS1 Antibodies)/CD47 (show CD47 Antibodies)/SIRP (show SIRPA Antibodies)-alpha signal axis is important to the evolution of tumor cells in the microenvironment of immunotherapy and identify thrombospondin-1 (show THBS1 Antibodies) as a key signal

  9. results identify WDR5 as a critical epigenomic integrator of histone phosphorylation and methylation and as a major driver of androgen-dependent prostate cancer cell proliferation

  10. BIG3(WRD5)-PHB2 (show PHB2 Antibodies) interaction is critical for the tamoxifen resistance of breast cancer cells; its targeting reverses the resistance.

Mouse (Murine) WD Repeat Domain 5 (WDR5) interaction partners

  1. Wdr5 suppression also reduced IFNgamma, Il-1beta (show IL1B Antibodies), and TNFalpha (show TNF Antibodies) induced chemokine (show CCL1 Antibodies) gene expression in b-cells without affecting islet-cell survival or b-cell function after 48hrs, but did begin to increase islet-cell apoptosis

  2. results suggest that specific RNAs are integral inputs into the WDR5-MLL (show MLL Antibodies) complex for maintenance of the active chromatin state and embryonic stem cell fates

  3. Data show that broad association of myc proto-oncogene protein MYC (show MYC Antibodies) with chromatin depends on interaction with the WD40 (show DCAF12L2 Antibodies)-repeat protein WDR5.

  4. BIG3 inhibits insulin (show INS Antibodies) granule biogenesis and insulin (show INS Antibodies) secretion.

  5. BIG3 negatively regulates insulin (show INS Antibodies) granule exocytosis by restricting insulin (show INS Antibodies) granule biogenesis without the release kinetics of individual granules at the final exocytotic steps being affected.

  6. Depletion of KAT2B (show KAT2B Antibodies) or WDR5 decreased gluconeogenic gene expression.

  7. analysis of a novel mechanism for epigenetic control of SMC (show DYM Antibodies)-marker gene expression during development through interaction of WDR5, homeodomain proteins, and chromatin remodeling enzymes

  8. Study shows that WD repeat domain 5 (Wdr5), a core member of the mammalian Trithorax (show MLLT1 Antibodies) (trxG) complex, positively correlates with the undifferentiated state and is a regulator of ES cell self-renewal.

  9. Characterization of a novel WDR5-binding site that recruits RbBP5 (show RBBP5 Antibodies) through a conserved motif to enhance methylation of histone H3 (show HIST3H3 Antibodies) lysine 4 by mixed lineage leukemia protein-1.

  10. WDR5 is essential in assembling a virus-induced VISA (show MAVS Antibodies)-associated complex and plays an important role in virus-triggered induction of type I interferons.

WDR5 Antigen Profile

Protein Summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.

Gene names and symbols associated with WDR5

  • WD repeat domain 5 (wdr5) antibody
  • WD repeat domain 5 (wdr5-a) antibody
  • WD repeat domain 5 (wdr5-b) antibody
  • WD repeat domain 5 (WDR5) antibody
  • WD repeat domain 5 (Wdr5) antibody
  • 2410008O07Rik antibody
  • AA408785 antibody
  • AA960360 antibody
  • Big antibody
  • Big-3 antibody
  • MGC80538 antibody
  • MGC81485 antibody
  • SWD3 antibody
  • wdr5-a antibody
  • wdr5-b antibody
  • wu:fk47f04 antibody
  • xwdr5 antibody
  • zgc:56591 antibody
  • zgc:76895 antibody

Protein level used designations for WDR5

WD repeat domain 5 , WD repeat-containing protein 5 , BMP2-induced 3-kb gene protein , SWD3, Set1c WD40 repeat protein, homolog , WD-repeat protein 5 , WD repeat-containing protein BIG-3

GENE ID SPECIES
406372 Danio rerio
446809 Xenopus laevis
447447 Xenopus laevis
496891 Xenopus (Silurana) tropicalis
11091 Homo sapiens
140858 Mus musculus
362093 Rattus norvegicus
100125836 Bos taurus
Selected quality suppliers for anti-WDR5 (WDR5) Antibodies
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