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WDR5 antibody (C-Term)

WDR5 Reactivity: Human ChIP, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6972909
$605.00
Plus shipping costs $45.00
100 μL
Shipping to: United States
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  • Target See all WDR5 Antibodies
    WDR5 (WD Repeat Domain 5 (WDR5))
    Binding Specificity
    • 11
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 65
    • 33
    • 25
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 59
    • 6
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 52
    • 15
    • 1
    Polyclonal
    Conjugate
    • 36
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This WDR5 antibody is un-conjugated
    Application
    • 45
    • 35
    • 10
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
    Characteristics
    WDR5 (WD repeat-containing protein 5) is a component of the Set1 histone methyltransferase / MLL1/MLL complex that is involved in methylation and dimethylation of 'Lys-4' of Histone H3. H3K4 methylation represents a specific tag for epigenetic transcriptional activation. WDR5 is also a component of the NSL complex and it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. WDR5 is also core component of other methyltransferase-containing complexes including MLL2/3 (also named ASCOM complex) and MLL4/WBP7. WDR5 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation and Western blot, it has been shown to react with Human samples.
    Purification
    Affinity Purified
    Immunogen
    This antibody was raised against a peptide within the C-terminal region of human WDR5.
    Isotype
    IgG
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    WDR5 (WD Repeat Domain 5 (WDR5))
    Alternative Name
    WDR5 (WDR5 Products)
    Synonyms
    BIG-3, SWD3, 2410008O07Rik, AA408785, AA960360, Big, Big-3, zgc:56591, zgc:76895, wu:fk47f04, wdr5-a, MGC80538, wdr5-b, MGC81485, big-3, swd3, xwdr5, WDR5B, WD repeat domain 5, WD repeat domain 5 L homeolog, WD repeat domain 5 S homeolog, WDR5, Wdr5, wdr5, wdr5.L, wdr5.S
    Background
    WDR5 (WD repeat-containing protein 5) is a component of the Set1 histone methyltransferase / MLL1/MLL complex that is involved in methylation and dimethylation of 'Lys-4' of Histone H3. H3K4 methylation represents a specific tag for epigenetic transcriptional activation. WDR5 is also a component of the NSL complex and it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. WDR5 is also core component of other methyltransferase-containing complexes including MLL2/3 (also named ASCOM complex) and MLL4/WBP7.
    Molecular Weight
    40 kDa
    NCBI Accession
    NP_060058
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