WDR5 antibody (C-Term)

Catalog No. ABIN6242698

Product Details anti-WDR5 Antibody

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Binding Specificity: AA 321-354, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR5 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, Rat, D

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This WDR5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 321-354 amino acids from the C-terminal region of human WDR5.

Clone: RB51448

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for WDR5

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Alternative Name: WDR5 (WDR5 Products)

Synonyms: BIG-3 antibody, SWD3 antibody, 2410008O07Rik antibody, AA408785 antibody, AA960360 antibody, Big antibody, Big-3 antibody, zgc:56591 antibody, zgc:76895 antibody, wu:fk47f04 antibody, wdr5-a antibody, MGC80538 antibody, wdr5-b antibody, MGC81485 antibody, big-3 antibody, swd3 antibody, xwdr5 antibody, WDR5B antibody, WD repeat domain 5 antibody, WD repeat domain 5 L homeolog antibody, WD repeat domain 5 S homeolog antibody, WDR5 antibody, Wdr5 antibody, wdr5 antibody, wdr5.L antibody, wdr5.S antibody

Background: Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

Molecular Weight: 36588

UniProt: P61964