WDR5 antibody (N-Term)

Catalog No. ABIN6266021

Product Details anti-WDR5 Antibody

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: WDR5 Antibody detects endogenous levels of total WDR5.

Predicted Reactivity: Pig,Bovine,Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human WDR5, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for WDR5

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Alternative Name: WDR5 (WDR5 Products)

Synonyms: BIG-3 antibody, SWD3 antibody, 2410008O07Rik antibody, AA408785 antibody, AA960360 antibody, Big antibody, Big-3 antibody, zgc:56591 antibody, zgc:76895 antibody, wu:fk47f04 antibody, wdr5-a antibody, MGC80538 antibody, wdr5-b antibody, MGC81485 antibody, big-3 antibody, swd3 antibody, xwdr5 antibody, WDR5B antibody, WD repeat domain 5 antibody, WD repeat domain 5 L homeolog antibody, WD repeat domain 5 S homeolog antibody, WDR5 antibody, Wdr5 antibody, wdr5 antibody, wdr5.L antibody, wdr5.S antibody

Background:

Description: Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

Gene: WDR5

Molecular Weight: 36kDa

Gene ID: 11091

UniProt: P61964