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The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. Additionally we are shipping WBP2 Antibodies (36) and many more products for this protein.
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Human WBP2 Protein expressed in Escherichia coli (E. coli) - ABIN1098390
Chen, Einbond, Kwak, Linn, Koepf, Peterson, Kelly, Sudol: Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands. in The Journal of biological chemistry 1997
Show all 2 references for ABIN1098390
The authors reported that the loss of Wbp2 expression leads to progressive high-frequency hearing loss in mouse, as well as in two deaf children, each carrying two different variants in the WBP2 gene.
data indicate that WBP-2 enhances ER transactivation function at certain genes by facilitating the recruitment and/or the stabilization of a histone modifier enzyme that favors a relaxed chromatin structure, permissive of transcription
The WW1 and WW2 domains of YAP2 (show YAP1 Proteins) recognize various PPXY motifs within WBP2 and WBP1 (show DDOST Proteins) in a highly promiscuous and subtle manner.
Data show that direct interaction of Wbp2 with TAZ (show TAZ Proteins) depends on the WW domain of TAZ (show TAZ Proteins).
WW domain binding protein-2, an E6-associated protein interacting protein, acts together with YAP (show YAP1 Proteins) as coactivators of estrogen and progesterone receptors.
This study established WBP2 as a tyrosine phosphorylation target of estrogen signaling via EGFR (show EGFR Proteins) crosstalk.
The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein, which binds to the WW domain of Yes kinase-associated protein by its PY motifs. The function of this protein has not been determined.
WW domain binding protein 2
, WW domain binding protein 2-like
, WW domain-binding protein 2