anti-WW and C2 Domain Containing 1 (WWC1) Antibodies

The protein encoded by WWC1 is a cytoplasmic phosphoprotein that interacts with PRKC-zeta and dynein light chain-1. Additionally we are shipping WW and C2 Domain Containing 1 Kits (11) and WW and C2 Domain Containing 1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
WWC1 23286 Q8IX03
WWC1 211652 Q5SXA9
WWC1    
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Top anti-WW and C2 Domain Containing 1 Antibodies at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-WWC1 Antibody Titration: 1.0 ug/ml Positive Control: PANC1 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WWC1 Antibody (N-term) (ABIN654697) western blot analysis in ZR-75-1 cell line lysates (35 µg/lane). This demonstrates the WWC1 antibody detected the WWC1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB WWC1 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35 µg/lane). This demonstrates the WWC1 antibody detected the WWC1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: KIBRA Antibody [NBP1-92052] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunocytochemistry/Immunofluorescence: KIBRA Antibody [NBP1-92052] - Staining of human cell line A-431 shows positivity in golgi apparatus. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-KIBRA Polyclonal Antibody, Unconjugated (ABIN1387477) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat kidney labeled with Anti-KIBRA Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Guinea Pig Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Cy3 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy5.5 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

WWC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-WW and C2 Domain Containing 1 Antibodies

  1. Human Polyclonal WWC1 Primary Antibody for ICC, IF - ABIN4328780 : Tanaka, Osada, Fujii, Fukatsu, Hida, Horio, Kondo, Sato, Hasegawa, Tsujimura, Sekido: LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade. in Oncogene 2015 (PubMed)

More Antibodies against WW and C2 Domain Containing 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) WW and C2 Domain Containing 1 (WWC1) interaction partners

  1. Merlin (show NF2 Antibodies) and Kibra activate Hippo signaling in parallel to Expanded at a spatially distinct cellular domain, the medial apical cortex.

  2. Kibra, a binding partner of Pez (show PTPN14 Antibodies), stabilizes Pez (show PTPN14 Antibodies) via WW-PY/PPxY interaction.

  3. Kibra regulates starvation-induced autophagy downstream of aPKC.

  4. In the human brain, KIBRA is mainly expressed in hippocampus and interacts with proteins involved in long-term potentiation and synaptic plasticity and effect memory in aged.

  5. The result reveals role for Kibra in neuronal specification and maintenance and show that the Hippo pathway is reimplemented for sensory neuron fate by combining canonical and noncanonical regulatory steps.

  6. Kibra functions as a tumor suppressor protein (show TP53 Antibodies) that regulates Hippo signaling in conjunction with Merlin (show NF2 Antibodies) and Expanded.

  7. Kibra is a regulator of the Salvador/Warts/Hippo signaling network.

  8. Kibra predominantly acts in the Merlin (show NF2 Antibodies) branch upstream of the core kinase cascade to regulate Hippo signaling.

Human WW and C2 Domain Containing 1 (WWC1) interaction partners

  1. Ability to navigate in the wilderness benefits from episodic memory (KIBRA).

  2. Study identifies four likely Tourette disorder risk genes with multiple de novo damaging variants in unrelated probands: WWC1 (WW and C2 domain containing 1), CELSR3 (Cadherin EGF LAG seven-pass G-type receptor 3 (show CELSR3 Antibodies)), NIPBL (show NIPBL Antibodies) (Nipped (show RPL38 Antibodies)-B-like), and FN1 (fibronectin 1 (show FN1 Antibodies)).

  3. study provides a mechanistic link between aberrant tau acetylation, KIBRA deficiency, and dementia in Alzheimer's disease

  4. show that KIBRA is overexpressed in human prostate tumors. Our studies uncover unexpected results and identify KIBRA as a tumor promoter in prostate cancer

  5. No significant differences in allelic or gene frequency distribution of KIBRA SNP rs17070145 were observed between schizophrenic and healthy control groups.

  6. WWC1 variants are involved in AMPA (show GRIA3 Antibodies) receptor trafficking and neuronal plasticity, which are associated with cognitive impairment and schizophrenia susceptibility.

  7. Study observed a trend for a better memory performance and significantly higher volumes and better microstructural integrity in the subfields comprising the CA2 (show CA2 Antibodies)/3 and CA4 (show CA4 Antibodies)/DG of the hippocampus in KIBRA T-allele carriers compared with non-T-carriers

  8. decreased expression of the KIBRA gene on both mRNA and protein levels in depression, is reported.

  9. Phosphorylation-dependent regulation of the DNA damage response of Kibra protein in cancer cells

  10. Study did not find support for an association of KIBRA either alone or in combination with CLSTN2 (show CLSTN2 Antibodies) with memory performance or hippocampal volume, nor did variation in these genes influence longitudinal memory decline or hippocampal atrophy in older adults

Mouse (Murine) WW and C2 Domain Containing 1 (WWC1) interaction partners

  1. study provides a mechanistic link between aberrant tau acetylation, KIBRA deficiency, and dementia in Alzheimer's disease

  2. KIBRA levels in the rodent hippocampus correlate closely both to spatial memory performance in rodents and to PKMzeta

  3. These results indicate that KIBRA regulates higher brain function by regulating AMPAR trafficking and synaptic plasticity.

  4. KIBRA associates with and activates Lats (large tumor suppressor (show LATS1 Antibodies)) 1 and 2 kinases by stimulating their phosphorylation on the hydrophobic motif

  5. KIBRA functions in memory performance via interaction with PKMzeta.

WW and C2 Domain Containing 1 (WWC1) Antigen Profile

Protein Summary

The protein encoded by this gene is a cytoplasmic phosphoprotein that interacts with PRKC-zeta and dynein light chain-1. Alleles of this gene have been found that enhance memory in some individuals. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with WWC1

  • kibra ortholog (kibra) antibody
  • WW and C2 domain containing 1 (WWC1) antibody
  • WW, C2 and coiled-coil domain containing 1 (Wwc1) antibody
  • AA408228 antibody
  • AU017197 antibody
  • BC037006 antibody
  • CG7552 antibody
  • CG12600 antibody
  • CG33967 antibody
  • Dmel\\CG33967 antibody
  • HBEBP3 antibody
  • HBEBP36 antibody
  • kib antibody
  • KIBRA antibody
  • l(3)02404 antibody
  • l(3)j5C3 antibody
  • l(3)neo42 antibody
  • mKIAA0869 antibody
  • ORE-2 antibody
  • RE26350 antibody

Protein level used designations for WWC1

CG33967-PA , kibra-PA , lethal (3) neo42 , HBeAg-binding protein 3 , WW, C2 and coiled-coil domain containing 1 , kidney and brain protein , protein KIBRA , protein WWC1 , WW domain-containing protein 1

GENE ID SPECIES
41783 Drosophila melanogaster
23286 Homo sapiens
211652 Mus musculus
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