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Wnt1 Inducible Signaling Pathway Protein 3 Proteins (WISP3)

WISP3 encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. Additionally we are shipping Wnt1 Inducible Signaling Pathway Protein 3 Antibodies (40) and Wnt1 Inducible Signaling Pathway Protein 3 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
WISP3 8838 O95389
Mouse WISP3 WISP3 327743 D3Z5L9
Rat WISP3 WISP3 499461  
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Top Wnt1 Inducible Signaling Pathway Protein 3 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 7 to 9 Days
$328.21
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   0.005 mg Log in to see 2 to 3 Days
$178.75
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 15 to 19 Days
$314.16
Details

WISP3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) Interaction Partners

Zebrafish Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) interaction partners

  1. One paralog of mammalian wisp3 was found in zebrafish.

  2. Overexpression of zebrafish Wisp3 protein inhibited bone morphogenetic protein (BMP) and Wnt signaling in developing zebrafish.

Human Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) interaction partners

  1. Studies indicate that the CYR61 (show CYR61 Proteins) CTGF (show CTGF Proteins) NOV (show NOV Proteins) matricellular proteins (CCN family of proteins) comprises the members CCN1 (show CCNA2 Proteins), CCN2 (show CTGF Proteins), CCN3 (show NOV Proteins), CCN4 (show WISP1 Proteins), CCN5 (show WISP2 Proteins) and CCN6 and have been identified in various types of cancer.

  2. WISP3 harbored not only frameshift mutation but also mutational intratumoral heterogeneity and loss of expression, which together might play a role in tumorigenesis of GC and CRC (show CALR Proteins) with MSI (show MSI1 Proteins)-H by inhibiting tumor suppressor functions of WISP3.

  3. WISP3 variant leads to the diagnosis of SEDT (show TRAPPC2 Proteins)-PA.

  4. Novel and recurrent mutations in WISP3 and an atypical phenotype have been described in Indian families with progressive pseudorheumatoid dysplasia.

  5. A novel mutation c.667T>G (p.Cys223Gly) and the c.857C>G (p.Ser286*) mutation were detected in three Chinese patients with PPD (show HPD Proteins).

  6. This study identified 3 different WISP3 mutations in 2 unrelated Chinese families with spondyloepiphyseal dysplasia tarda with progressive arthropathy.

  7. Suggest WISP3-Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) axis may have role in regulating gastric cancer cell proliferation and metastasis.

  8. Novel C223G and C252X mutations in exon 4 of the WISP3 gene are responsible for progressive pseudorheumatoid dysplasia in Chinese patients.

  9. Results are indicative of an operational WISP3-IGF1 (show IGF1 Proteins) regulatory loop whereby WISP3 preserves cartilage integrity by restricting IGF1 (show IGF1 Proteins)-mediated hypertrophic changes in chondrocytes, at least partly, upon interaction with IGF1 (show IGF1 Proteins).

  10. A report on 11 different homozygous mutations and one instance of compound heterozygosity in the WISP3 gene in patients with progressive pseudorheumatoid dysplasia.

Mouse (Murine) Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) interaction partners

  1. demonstrated that CCN6 induced the proliferation of lung fibroblasts by binding to integrin beta1, leading to the phosphorylation of FAK (show PTK2 Proteins)(Y397).

  2. the WISP3 gene is essential to skeletal growth or homeostasis in humans but not in mice [WISP3]

Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) Protein Profile

Protein Summary

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with WISP3

  • WNT1 inducible signaling pathway protein 3 (wisp3)
  • WNT1 inducible signaling pathway protein 3 (WISP3)
  • WNT1 inducible signaling pathway protein 3 (Wisp3)
  • CCN6 protein
  • ENSMUSG00000062074 protein
  • Gm735 protein
  • LIBC protein
  • PPAC protein
  • PPD protein
  • RGD1564120 protein
  • si:dkey-119m7.6 protein
  • WISP-3 protein
  • WISP3 protein

Protein level used designations for WISP3

WNT1 inducible signaling pathway protein 3 , WNT1-inducible-signaling pathway protein 3 , WNT1-inducible-signaling pathway protein 3-like , CCN family member 6 , WISP-3

GENE ID SPECIES
566864 Danio rerio
695430 Macaca mulatta
741440 Pan troglodytes
770827 Gallus gallus
784564 Bos taurus
794092 Danio rerio
100072430 Equus caballus
100124323 Xenopus (Silurana) tropicalis
100440568 Pongo abelii
8838 Homo sapiens
327743 Mus musculus
499461 Rattus norvegicus
100686448 Canis lupus familiaris
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