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WISP3 Products

(Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

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This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured WISP3 Categories

WISP3 Antibodies

High quality antibodies with extensive validation data.

WISP3 ELISA Kits

Reliable ELISA kits for a wide range of species.

WISP3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended WISP3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7175855
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN390189
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7189408
Quantity 100 μg
Datasheet Datasheet

Recommended WISP3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971205
Quantity 96 tests
Datasheet Datasheet

Recommended WISP3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN5509802
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325345
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3075479
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our WISP3 products

Ji, Jia, Jia, Ji, Hargest, Jiang: "WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-? pathways." in: British journal of cancer, Vol. 113, Issue 6, pp. 921-33, (2015) (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).

Kleer, Zhang, Pan, van Golen, Wu, Livant, Merajver: "WISP3 is a novel tumor suppressor gene of inflammatory breast cancer." in: Oncogene, Vol. 21, Issue 20, pp. 3172-80, (2002) (PubMed).

Tanaka, Sugimachi, Shimada, Maehara, Sugimachi: "Variant WISPs as targets for gastrointestinal carcinomas." in: Gastroenterology, Vol. 123, Issue 1, pp. 392-3, (2002) (PubMed).

Synonyms and alternative names related to WISP3

WNT1 inducible signaling pathway protein 3 (WISP3), WNT1 inducible signaling pathway protein 3 (Wisp3), WNT1 inducible signaling pathway protein 3 (wisp3), CCN6, ENSMUSG00000062074, Gm735, LIBC, PPAC, PPD, RGD1564120, si:dkey-119m7.6, WISP-3, WISP3

Protein level used designations for WISP3

  • CCN family member 6
  • WISP-3
  • WNT1-inducible-signaling pathway protein 3
  • WNT1 inducible signaling pathway protein 3
  • WNT1-inducible-signaling pathway protein 3-like
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