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Involved in proliferation and apoptosis in myeloid precursor cells (By similarity). Additionally we are shipping Yippee-Like 3 (Drosophila) Proteins (4) and many more products for this protein.
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Human Polyclonal YPEL3 Primary Antibody for EIA, IF - ABIN1450137
Hosono, Sasaki, Minoshima, Shimizu: Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species. in Gene 2004
Studies with mouse YPEL3, originally named small unstable apoptot (show ARHGAP24 Antibodies)ic prote (show CKAP4 Antibodies)in (SUAP), confirmed th (show TP53 Antibodies)at the gene encodes a growth suppressive highly unstable protein.[review]
YPEL3 expression, which is induced by the removal of estrogen or treatment with tamoxifen triggers cellular senescence in MCF-7 cells while loss of YPEL3 increases the growth rate of MCF-7 cells.
YPEL3 is downregulated in colon tumors.
In this review we show that transcriptionally active forms of p73 (show TP73 Antibodies) and p63 (show RPE65 Antibodies), family members of p53 (show TP53 Antibodies), can transactivate the human YPEL3 gene[review]
Findings point to YPEL3 being a novel tumor suppressor, which upon induction triggers a permanent growth arrest in human tumor and normal cells.
Involved in proliferation and apoptosis in myeloid precursor cells (By similarity).
protein yippee-like 3
, small ubiquitinated apoptotic protein
, yippee-like 3