YPEL3 antibody (N-Term)

Catalog No. ABIN6991665

Product Details anti-YPEL3 Antibody

Target: YPEL3 (Yippee-Like 3 (YPEL3))

Binding Specificity: AA 20-70, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YPEL3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Purification: YPEL3 Antibody is affinity chromatography purified via peptide column.

Immunogen: YPEL3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human YPEL3. The immunogen is located within amino acids 20 - 70 of YPEL3.

Isotype: IgG

Application Details

Application Notes: YPEL3 antibody can be used for detection of YPEL3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: YPEL3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: YPEL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for YPEL3

Target: YPEL3 (Yippee-Like 3 (YPEL3))

Alternative Name: YPEL3 (YPEL3 Products)

Synonyms: 0610043B10Rik antibody, 1190001G19Rik antibody, Suap antibody, RGD1564579 antibody, yippee-like 3 (Drosophila) antibody, yippee like 3 antibody, yippee-like 3 antibody, Ypel3 antibody, YPEL3 antibody

Background: YPEL3 Antibody: YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.

Gene ID: 83719

NCBI Accession: NP_113665

UniProt: P61236