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Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. Additionally we are shipping Zinc Finger, CCHC Domain Containing 12 Proteins (4) and many more products for this protein.
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Cow (Bovine) Polyclonal ZCCHC12 Primary Antibody for WB - ABIN2785325
Cho, Lim, Zand, Golden: Sizn1 is a novel protein that functions as a transcriptional coactivator of bone morphogenic protein signaling. in Molecular and cellular biology 2008
The ZCCHC12 gene may be a novel diagnostic molecular marker of primary papillary thyroid carcinoma
data implicate SIZN1 as a candidate gene for X-linked mental retardation and/or as a neurocognitive functional modifier
Data indicate that the SIMs in Sizn1 are required for its PML-NB localization and for the full transcriptional co-activation function in BMP signaling.
ZCCHC12 enhanced the transcriptional activities of activator protein 1 (AP-1) and cAMP response element binding protein (CREB) as a coactivator
Sizn1 is expressed by Cajal-Retzius neurons of the dorsal forebrain, beginning in their progenitor zones
Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression (By similarity).
zinc finger, CCHC domain containing 12
, zinc finger CCHC domain-containing protein 12-like
, paraneoplastic Ma antigen family member 7A
, smad-interacting zinc finger protein 1
, zinc finger CCHC domain-containing protein 12