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anti-Zinc Finger, DHHC-Type Containing 17 (ZDHHC17) Antibodies

Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HD. Additionally we are shipping Zinc Finger, DHHC-Type Containing 17 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZDHHC17 320150 Q80TN5
ZDHHC17 23390 Q8IUH5
ZDHHC17 366889  
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Top anti-Zinc Finger, DHHC-Type Containing 17 Antibodies at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-ZDHHC17 Antibody Titration: 0.2-1 ug/mlPositive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN185335 (1µg/ml) staining of Mouse Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Dog Rabbit Un-conjugated WB Figure 1. Western Blot using ZDHHC17 antibody (at 1/1000 dilution): Sample(30 µg whole cell lysate) A: Hela B: HepG2 7.5% SDS PAGE. 0.1 mL Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB ZDHHC17 antibody used at 5 ug/ml to detect target protein. 100 μg Log in to see 3 to 4 Days
$388.93
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 14 Days
$527.15
Details

ZDHHC17 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Human
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, , , , ,
Rat (Rattus)
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Top referenced anti-Zinc Finger, DHHC-Type Containing 17 Antibodies

  1. Chicken Polyclonal ZDHHC17 Primary Antibody for WB - ABIN2782843 : Metzger, Bauer, Tomiuk, Laccone, Didonato, Gellera, Mariotti, Lange, Weirich-Schwaiger, Wenning, Seppi, Melegh, Havasi, Balikó, Wieczorek, Zaremba, Hoffman-Zacharska, Sulek, Basak, Soydan, Zidovska, Kebrdlova, Pandolfo, Ribaï, Kadasi, Kvasnicova, Weber, K: Genetic analysis of candidate genes modifying the age-at-onset in Huntington's disease. in Human genetics 2006 (PubMed)

  2. Dog (Canine) Polyclonal ZDHHC17 Primary Antibody for WB - ABIN374510 : Huang, Yanai, Kang, Arstikaitis, Singaraja, Metzler, Mullard, Haigh, Gauthier-Campbell, Gutekunst, Hayden, El-Husseini: Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins. in Neuron 2004 (PubMed)

More Antibodies against Zinc Finger, DHHC-Type Containing 17 Interaction Partners

Mouse (Murine) Zinc Finger, DHHC-Type Containing 17 (ZDHHC17) interaction partners

  1. The findings of this study identify ZDHHC17 as an important upstream factor of ERK1/2 (show MAPK1/3 Antibodies) to regulate the interaction between TrkA (show NTRK1 Antibodies) and tubulin (show TUBB Antibodies) during neuronal development.

  2. Data show that the ankyrin repeat (AR) domains of S-acyltransferases zDHHC17 and zDHHC13 (show ZDHHC13 Antibodies) recognize peptide sequence in several unrelated proteins.

  3. Loss of Hip14 and Hip14l (show ZDHHC13 Antibodies) leads to early embryonic lethality at day embryonic day 10-11 due to failed chorioallantoic fusion.

  4. Data indicate that thioesterases APT1 (show FAS Antibodies)/APT2 (show TAP2 Antibodies) depalmitoylate nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2 (show NMNAT2 Antibodies)) and zDHHC17 is the strongest candidate palmitoyltransferase for NMNAT2 (show NMNAT2 Antibodies).

  5. In the absence of HIP14, striatal neurons become dysfunctional, leading to impaired motor behavior.

  6. The constitutive absence of Hip14/DHHC17 results in major neurophysiological deficits and associated cognitive dysfunction.

  7. altered palmitoylation mediated by HIP14 may contribute to HD.

  8. Wild-type HTT (show HTT Antibodies) modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14.

  9. Immunohistochemical analysis of pancreatic sections demonstrated that HIP14 is almost exclusively expressed in insulin (show INS Antibodies)-positive cells in islets of Langerhans.

  10. Downregulation of HIP14 in mouse neurons expressing wild-type and mutant htt (show HTT Antibodies) increases inclusion formation, whereas overexpression of HIP14 substantially reduces inclusions

Human Zinc Finger, DHHC-Type Containing 17 (ZDHHC17) interaction partners

  1. This suggests that altered HIP14-HTT (show HTT Antibodies) and HIP14L (show ZDHHC13 Antibodies)-HTT (show HTT Antibodies) interactions in the presence of the HD mutation reduces palmitoylation and promotes mislocalization of HTT (show HTT Antibodies) and other HIP14/HIP14L (show ZDHHC13 Antibodies) substrates

  2. Data show that deletion of huntingtin (show HTT Antibodies) protein (HTT (show HTT Antibodies)) amino acids 1-427 abolishes the interaction of HTT (show HTT Antibodies) with palmitoyl acyltransferases huntingtin interacting protein 14 (HIP14) and huntingtin interacting protein 14-like (HIP14L (show ZDHHC13 Antibodies)).

  3. HIP14 shares a high proportion of interactors with HTT (show HTT Antibodies) resulting in defective palmitoylation of the target proteins which might be an important mechanism towards pathogenesis of Huntington's disease.

  4. DHHC17 is a ClipR-59 (show CLIP3 Antibodies) palmitoyltransferase that modulates ClipR-59 (show CLIP3 Antibodies) plasma membrane binding.

  5. Low levels of human HIP14 are sufficient to rescue neuropathological, behavioural, and enzymatic defects due to loss of murine HIP14 in Hip14-/- mice.

  6. Immunohistochemical analysis of pancreatic sections demonstrated that HIP14 is almost exclusively expressed in insulin (show INS Antibodies)-positive cells in islets of Langerhans.

  7. Novel peptides have been developed that target the jun (show JUN Antibodies) N-terminus kinase (JNK (show MAPK8 Antibodies))-interacting motif on zD17 to selectively block enhancement of the zD17-Jun (show JUN Antibodies) N terminus kinase (JNK (show MAPK8 Antibodies)) interaction and the activation of JNK (show MAPK8 Antibodies) isoforms 2 and 3.

  8. a subset of DHHCs controls STREX palmitoylation and function; DHHC17 may preferentially target cysteine-rich domains

  9. Coexpression of an independent palmitoyl acyltransferase (HIP14) with the GODZ (show ZDHHC3 Antibodies)-DHHS mutant also rescued Ca(2 (show CA2 Antibodies)+) transport.

  10. HIP14 is a protein: palmitoyl acyltransferase

Zinc Finger, DHHC-Type Containing 17 (ZDHHC17) Antigen Profile

Protein Summary

Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HD. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. Has transforming activity. Mediates Mg(2+) transport (By similarity).

Gene names and symbols associated with ZDHHC17

  • zinc finger, DHHC-type containing 17 (ZDHHC17) antibody
  • zinc finger, DHHC-type containing 17 (zdhhc17) antibody
  • zinc finger, DHHC domain containing 17 (Zdhhc17) antibody
  • zinc finger, DHHC-type containing 17 (Zdhhc17) antibody
  • A230053P19Rik antibody
  • BB187739 antibody
  • D130071N24Rik antibody
  • HIP3 antibody
  • HIP14 antibody
  • HYPH antibody
  • si:ch211-81a6.1 antibody

Protein level used designations for ZDHHC17

zinc finger, DHHC-type containing 17 , huntingtin interacting protein 14 , palmitoyltransferase ZDHHC17-like , DHHC-17 , huntingtin-interacting protein 14 , palmitoyltransferase ZDHHC17 , zinc finger DHHC domain-containing protein 17 , HIP-14 , HIP-3 , Huntingtin interacting protein H , huntingtin interacting protein 3 , huntingtin yeast partner H , huntingtin-interacting protein 3 , huntingtin-interacting protein H , putative MAPK-activating protein PM11 , putative NF-kappa-B-activating protein 205 , zinc finger, DHHC domain containing 17 , membrane-associated DHHC17 zinc finger protein

GENE ID SPECIES
452088 Pan troglodytes
693595 Macaca mulatta
100059245 Equus caballus
100348308 Oryctolagus cuniculus
100441489 Pongo abelii
100482435 Ailuropoda melanoleuca
100486328 Xenopus (Silurana) tropicalis
100538815 Meleagris gallopavo
100566493 Anolis carolinensis
100597842 Nomascus leucogenys
320150 Mus musculus
23390 Homo sapiens
100148543 Danio rerio
417867 Gallus gallus
541172 Bos taurus
366889 Rattus norvegicus
482574 Canis lupus familiaris
100514712 Sus scrofa
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