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Palmitoyltransferase with broad specificity. Additionally we are shipping and many more products for this protein.
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Human Polyclonal ZDHHC3 Primary Antibody for EIA, WB - ABIN955650
Hines, Kang, Goytain, Quamme: Golgi-specific DHHC zinc finger protein GODZ mediates membrane Ca2+ transport. in The Journal of biological chemistry 2010
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Findings highlight that FGFR (show FGFR2 Antibodies)- and Src (show SRC Antibodies)-mediated tyrosine phosphorylation of ZDHHC3 modulates ZDHHC3 enzymatic activity and plays a role in neuronal morphogenesis.
coordination of zinc ions by cysteine residues within the cysteine-rich domain is required for the structural integrity of DHHC3
In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin (show NCDN Antibodies) palmitoylation in its targeting to Rab5 (show RAB5A Antibodies)-positive endosomes.
Data conclude that GODZ encodes a Ca(2 (show CA2 Antibodies)+) transport protein in addition to its ability to palmitoylate protein substrates.
identified a novel Golgi apparatus-specific protein, designated as GODZ, which may play a role in membrane protein trafficking (GODZ)
GODZ-mediated palmitoylation is a novel posttranslational modification that is selective for gamma-subunit-containing GABA(A) receptor subtypes, a mechanism that may be important for regulated trafficking of these receptors in the secretory pathway.
GODZ-mediated palmitoylation of GABA(A) receptor gamma 2 subunit (show GABRG2 Antibodies), and possibly other substrates, contributes selectively to the formation and normal function of GABAergic inhibitory synapses.
GODZ regulates plasma membrane targeting of DR4 (show HLADRB4 Antibodies) and thus TRAIL/DR4 (show HLADRB4 Antibodies)-mediated apoptosis in cancer cells.
Palmitoylation by DHHC3 is critical for the function, expression, and stability of integrin alpha6beta4.
Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi.
zinc finger, DHHC-type containing 3
, zinc finger, DHHC domain containing 3
, DHHC1 protein
, palmitoyltransferase ZDHHC3
, GABA-A receptor-associated membrane protein 1
, golgi-specific DHHC zinc finger protein
, zinc finger DHHC domain-containing protein 3
, Golgi apparatus-specific protein with DHHC zinc finger domain
, golgi-specific DHHC Zinc Finger Protein
, zinc finger protein 373