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The ZFYVE16 gene encodes endofin, an endosomal protein implicated in regulating membrane trafficking. Additionally we are shipping Zinc Finger, FYVE Domain Containing 16 Proteins (3) and many more products for this protein.
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Human Polyclonal ZFYVE16 Primary Antibody for FACS, IHC (p) - ABIN651313
Chen, Low, Choong, Ray, Tan, Toy, Lin, Ang, Wong, Lim, Li, Hew, Sze, Druker, Lim: Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells. in Proteomics 2007
Show all 2 references for ABIN651313
Disruption of proper localization to the endosomes and the Y515 phosphorylation of Endofin enhanced MAPK (show MAPK1 Antibodies) activation suggesting that Endofin negatively modulates EGFR (show EGFR Antibodies) signaling following receptor endocytosis.
marked recruitment of TOM1 (show TOM1 Antibodies) to endosomes was observed in cells overexpressing endofin or its carboxyl-terminal fragment
The key mode of action of Trx (show VAC14 Antibodies)-SARA (show ZFYVE9 Antibodies) was to reduce the level of Smad2 (show SMAD2 Antibodies) and Smad3 (show SMAD3 Antibodies) in complex with Smad4 (show SMAD4 Antibodies) after TGF-beta1 (show TGFB1 Antibodies) stimulation.
Facilitates TGF-beta (show TGFB1 Antibodies) signaling as a scaffold protein (show HOMER1 Antibodies) to promote the R-Smad (show SMAD1 Antibodies)-Smad4 (show SMAD4 Antibodies) complex formation by bringing Smad4 (show SMAD4 Antibodies) to the proximity of the receptor complex.
our study is the first to identify and validate Endofin, DCBLD2 (show DCBLD2 Antibodies), and KIAA0582 as part of a complex EGF (show EGF Antibodies) phosphotyrosine signaling network
The ZFYVE16 gene encodes endofin, an endosomal protein implicated in regulating membrane trafficking. It is characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain positioned in the middle of the molecule (Seet et al., 2004
zinc finger FYVE domain-containing protein 16
, endosome-associated FYVE-domain protein
, zinc finger, FYVE domain containing 16
, zinc finger FYVE domain-containing protein 16-like
, endosome-associated FYVE domain protein
, protein phosphatase 1, regulatory subunit 69
, endosomal-associated FYVE domain protein