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Zinc Finger, FYVE Domain Containing 9 Proteins (ZFYVE9)

ZFYVE9 encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. Additionally we are shipping ZFYVE9 Antibodies (33) and ZFYVE9 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse ZFYVE9 ZFYVE9 230597  
Rat ZFYVE9 ZFYVE9 313477  
ZFYVE9 9372 O95405
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Top ZFYVE9 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Fruit Fly Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

ZFYVE9 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Zinc Finger, FYVE Domain Containing 9 (ZFYVE9) Interaction Partners

Fruit Fly (Drosophila melanogaster) Zinc Finger, FYVE Domain Containing 9 (ZFYVE9) interaction partners

  1. Notch (show NOTCH1 Proteins) binds Uninflatable, and both traffic together through Sara endosomes, which is essential to direct asymmetric endosomes motility and Notch (show NOTCH1 Proteins)-dependent cell fate assignation.

  2. Sara itself contributes to the control of the intestinal stem cells asymmetric division.

  3. PP1 (show PPYR1 Proteins) binds Sara and negatively regulates Dpp (show TGFb Proteins) signaling in Drosophila melanogaster.

  4. During mitosis, Sara endosomes associate with the spindle machinery to segregate into the two daughter cells, daughter cells thereby inherited equal amounts of signaling molecules and retained the Dpp (show TGFb Proteins) signaling levels of the mother cell

  5. asymmetric targeting of Delta and Notch (show NOTCH1 Proteins)-containing Sara endosomes will increase Notch (show NOTCH1 Proteins) signalling in sensory organ precursor daughter cell, pIIa, and decrease it in pIIb

Mouse (Murine) Zinc Finger, FYVE Domain Containing 9 (ZFYVE9) interaction partners

  1. This study describes the expression of two SARA (show SAR1A Proteins) isoforms, SARA1 (show SAR1A Proteins) and SARA2 (show SAR1B Proteins), in mice and reports the generation and characterization of SARA (show SAR1A Proteins) mutant mice with FYVE domain deletion. The loss of SARA (show SAR1A Proteins) promoted skin tumor formation and malignant progression.

  2. osteoblast targeted expression of a mutant endofin protein lacking the pp1c binding activity results in sustained signaling of the BMP type I receptor, which increases bone formation and skeletal angiogenesis.

Human Zinc Finger, FYVE Domain Containing 9 (ZFYVE9) interaction partners

  1. we have identified endofin (show ZFYVE16 Proteins) as an important signalling component required for basal and BMP-induced hepcidin (show HAMP Proteins) expression.

  2. SARA may serve as a potential novel target in pre-Epithelial-mesenchymal transition states for the amelioration renal fibrosis seen in chronic kidney diseases

  3. PI3K (show PIK3CA Proteins)-C2a was also required for TGFb (show TGFB1 Proteins) receptor-mediated formation of SARA-Smad2 (show SMAD2 Proteins)/3 complex

  4. The negative influence that perturbation of RNF11 (show RNF11 Proteins) and SARA levels exerts on the lysosomal degradation of EGFRs could underscore the significance of overexpression of RNF11 (show RNF11 Proteins) in certain cancers.

  5. TGF-beta1 (show TGFB1 Proteins) can induce epithelial-to-mesenchymal transition through reduction in SARA expression, SARA is also basally regulated by its interaction with PI3K (show PIK3CA Proteins).

  6. no correlation between SARA expression and the levels of TGF-beta1 (show TGFB1 Proteins)-induced phosphorylation of Smads in various B-cell lymphomas

  7. SARA binds to ERBIN (show ERBB2IP Proteins) using a new domain, which we have called the ERBID (ERBIN (show ERBB2IP Proteins)-binding domain)

  8. After stimulation with glucose, expression of SARA decreased in a time-dependent manner in epithelium to mesenchymal transition of proximal tubule cells.

  9. Expression of a SARA mutant protein lacking the FYVE finger inhibits downstream activin A (show INHBA Proteins) signaling in endothelial cells.

  10. role in rab5 (show RAB5A Proteins) mediated endocytosis

ZFYVE9 Protein Profile

Protein Summary

This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ZFYVE9

  • Smad anchor for receptor activation (Sara)
  • zinc finger, FYVE domain containing 9 (Zfyve9)
  • zinc finger, FYVE domain containing 9 (ZFYVE9)
  • CG15667 protein
  • Dmel\\CG15667 protein
  • dSARA protein
  • E030027L17 protein
  • MADHIP protein
  • NSP protein
  • sara protein
  • SMADIP protein

Protein level used designations for ZFYVE9

CG15667-PA , CG15667-PB , Sara-PA , Sara-PB , smad anchor for receptor activation , MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor , zinc finger FYVE domain-containing protein 9 , MADH-interacting protein , novel serine protease

GENE ID SPECIES
44263 Drosophila melanogaster
230597 Mus musculus
313477 Rattus norvegicus
9372 Homo sapiens
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