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Zinc Finger Protein, X-Linked Proteins (ZFX)

ZFX on the X chromosome is structurally similar to a related gene on the Y chromosome. Additionally we are shipping ZFX Antibodies (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse ZFX ZFX 22764 P17012
Rat ZFX ZFX 367832  
ZFX 7543 P17010
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Top ZFX Proteins at

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 39 to 44 Days
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days

ZFX Proteins by Origin and Source

Origin Expressed in Conjugate

More Proteins for Zinc Finger Protein, X-Linked (ZFX) Interaction Partners

Mouse (Murine) Zinc Finger Protein, X-Linked (ZFX) interaction partners

  1. Zfx is a common cell-intrinsic regulator of diverse Hedgehog (show SHH Proteins)-induced tumors.

  2. Zfx, a transcription factor that controls hematopoietic stem cell self-renewal, controls the initiation and maintenance of acute myeloid leukemia (show BCL11A Proteins).

  3. These studies identify Zfx as a shared transcriptional regulator of embryonic stem cells and hematopoietic stem cells, suggesting a common genetic basis of self-renewal in embryonic and adult SC.

  4. Zfx restrains the stress response and couples antigen receptor signaling to cell expansion and maintenance during B-cell development and peripheral homeostasis

Human Zinc Finger Protein, X-Linked (ZFX) interaction partners

  1. ZFX expression may have a role in poor prognosis of renal cell carcinoma (show MOK Proteins) patients

  2. Nasopharyngeal carcinoma patients with high ZFX expression had lower 5-year overall survival rates, progression-free survival rates, loco-regional relapse-free survival rates and distant metastasis-free survival rates than those with low ZFX expression

  3. Our results provide evidence suggesting that ZFX overexpression is associated with the development of tongue SCC and ZFX knockdown is a potential treatment for tumor suppression

  4. These data demonstrate that ZFX functions as a critical upstream regulator of c-Myc (show MYC Proteins) and plays essential roles in the maintenance of the glioma stem cells phenotype

  5. ZFX is essential for the development and progression of squamous cell carcinoma of the tongue.

  6. our findings for the first time demonstrated that ZFX expression may be associated with the progress of colorectal cancer

  7. Study detected the expression of ZFX in 42 patients with renal cancer and found the expression of ZFX was specifically upregulated in cancer tissues at the mRNA and protein levels.

  8. Expression of ZFX promotes tumor growth in hepatocellular carcinoma.

  9. ZFX knockdown prevented tumor cell growth and migration in vitro and decreased proportion of tumor bearing mice and reduced mean tumor volume in a subcutaneous tumor model.

  10. ZFX is over-expressed in children with B-acute lymphoblastic leukemia and its levels are higher in those with a poor prognosis than those with a good prognosis

Cow (Bovine) Zinc Finger Protein, X-Linked (ZFX) interaction partners

  1. ZFX transcripts were noted in all pre-compaction stage embryos and in female and male blastocysts; the expression of ZFX was significantly higher in female than in male blastocysts

ZFX Protein Profile

Protein Summary

This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.

Gene names and symbols associated with ZFX

  • zinc finger protein X-linked (Zfx)
  • zinc finger protein, X-linked (zfx)
  • zinc finger protein, X-linked (ZFX)
  • RGD1562664 protein
  • xzfy-1 protein
  • Zfx5 protein
  • Zfx5,6 protein
  • Zfx6 protein
  • zfy1 protein
  • ZNF926 protein

Protein level used designations for ZFX

X-linked zinc finger protein , zinc finger X-chromosomal protein , zinc finger protein X-linked 5 , zinc finger protein X-linked 6 , ZFY-1 , zinc finger Y-chromosomal protein 1 , zinc finger protein 1, Y linked , zinc finger protein X-linked , Zinc finger X-chromosomal protein , zinc finger protein ZFX

22764 Mus musculus
367832 Rattus norvegicus
397971 Xenopus laevis
7543 Homo sapiens
280961 Bos taurus
397294 Sus scrofa
491778 Canis lupus familiaris
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