Zinc Finger Protein 384 Proteins (ZNF384)

ZNF384 encodes a C2H2-type zinc finger protein, which may function as a transcription factor. Additionally we are shipping Zinc Finger Protein 384 Antibodies (58) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ZNF384 171017 Q8TF68
Mouse ZNF384 ZNF384 269800  
ZNF384 171018 Q9EQJ4
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Top Zinc Finger Protein 384 Proteins at antibodies-online.com

Showing 5 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Escherichia coli (E. coli) Human GST tag   50 μg Log in to see 11 Days
$341.00
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HOST_Escherichia coli (E. coli) Human GST tag 1 mg Log in to see 11 to 14 Days
$1,842.50
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,663.00
Details
HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$736.00
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ZNF384 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Rat (Rattus)

More Proteins for Zinc Finger Protein 384 (ZNF384) Interaction Partners

Human Zinc Finger Protein 384 (ZNF384) interaction partners

  1. EP300 (show EP300 Proteins)-ZNF384 mediates GATA3 (show GATA3 Proteins) gene expression and may be involved in the acquisition of the HSC (show FUT1 Proteins) gene expression signature and characteristic immunophenotype in B-cell precursor acute lymphoblastic leukemia cells.

  2. Our observations indicate that ZNF384-related fusion genes consist of a distinct subgroup of B-cell precursor acute lymphoblastic leukemia with a characteristic immunophenotype, while the clinical features depend on the functional properties of individual fusion partners.

  3. the frequency of ZNF384 gene rearrangement in pediatric precursor B cell ALL is approximately 3%.

  4. nuclear matrix protein 4 overexpression increased Aquaporin 5 (show AQP5 Proteins) mRNA expression by 2.5-fold in HEK293 cells

  5. Rare translocation t(12;17)(p13;q12), This translocation has been reported in 25 cases and its putative molecular consequence, the formation of a TAF15 (show TAF15 Proteins)-ZNF384 fusion gene, in only six cases.

  6. The transcription factor gene CIZ/NMP4 is recurrently involved in acute leukemia through fusion with either EWSR1 (show EWSR1 Proteins) or TAF15 (show TAF15 Proteins).

  7. The CIZ protein(also known as ZNF384)was involved and rearrangemented in acute leukemia.

  8. These results suggest that caspase (show CASP3 Proteins)-mediated degradation may represent a novel regulatory mechanism that controls TAF15 (show TAF15 Proteins) and TAF15 (show TAF15 Proteins)-CIZ/NMP4 activities.

Mouse (Murine) Zinc Finger Protein 384 (ZNF384) interaction partners

  1. The heightened osteoanabolism of the Nmp4-/- skeleton enhances the effectiveness of diverse osteoporosis treatments, in part by increasing hyperanabolic osteoprogenitors. Nmp4 provides a promising target pathway for identifying barriers to pharmacologically induced bone formation.

  2. Sustained protein synthesis sensitized cells to pharmacological induction of the Unfolded Protein Response (UPR), and the observed decrease in cell viability was restored upon inhibition of GADD34 (show PPP1R15A Proteins) activity. We conclude that NMP4 is a key regulator of ribosome biogenesis and the UPR, which together play a central role in determining cell viability during endoplasmic reticulum stress.

  3. NMP4 deficiency suppressed the arthritis-induced increase in bone resorption, expression of RANKL (show TNFSF11 Proteins) and MMP-3 (show MMP3 Proteins) mRNA.

  4. Nmp4/CIZ limits the parathyroid hormone (show PTH Proteins) anabolic window by restricting the number of bone marrow stem, progenitor, and blood cells that support anabolic bone remodeling.

  5. The CIZ/NMP4 expression levels are correlated to the metastatic activity in divergent types of melanoma cells.

  6. Together these results provide experimental support for the concept that Nmp4/CIZ plays an inhibitory role in the response of bone cells to mechanical stimulation induced by OFSS.

  7. Nmp4/CIZ within the context of the PTH (show PTH Proteins)-induced anabolic response is described.

  8. Impaired spermatogenesis and male infertility occurred in Nmp4-disrupted mice.

  9. transformation of 3T3 fibroblasts by CIZ/NMP4 fusions is dependent on DNA-binding and might involve transactivation of CIZ target genes

  10. Two adjacent promoters of Nmp4 P(1) [-2521 nucleotide (nt)/-597 nt] and P(2) (-2521 nt/+1 nt) initiate transcription of alternative first exons (U(1) and U(2)).

Zinc Finger Protein 384 (ZNF384) Protein Profile

Protein Summary

This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.

Gene names and symbols associated with ZNF384

  • zinc finger protein 384 (ZNF384)
  • zinc finger protein 384 (Zfp384)
  • zinc finger protein 384 (znf384)
  • BB163993 protein
  • C130073D16Rik protein
  • CAGH1 protein
  • CAGH1A protein
  • Ciz protein
  • ERDA2 protein
  • Nmp4 protein
  • NP protein
  • TNRC1 protein
  • Znf384 protein

Protein level used designations for ZNF384

CAG repeat protein 1 , Cas-interacting zinc finger protein , expanded repeat domain, CAG/CTG 2 , nuclear matrix transcription factor 4 , trinucleotide repeat-containing gene 1 protein , nuclear matrix protein 4 , Cas-associated zinc finger protein

GENE ID SPECIES
171017 Homo sapiens
269800 Mus musculus
171018 Rattus norvegicus
446592 Xenopus laevis
515007 Bos taurus
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