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May be involved in transcriptional regulation.. Additionally we are shipping Zinc Finger Protein 580 Antibodies (26) and many more products for this protein.
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These results suggest that ZNF580 mediates eNOS (show NOS3 Proteins) expression and endothelial cell migration/proliferation via the TGF-b1/ALK5 (show TGFBR1 Proteins)/Smad2 (show SMAD2 Proteins) pathway, and thus plays a crucial role in vascular endothelial cells.
H2O2 upregulates the expression of ZNF580 via the NF-kappaB (show NFKB1 Proteins) signaling pathway, and overexpression of ZNF580 plays a critical role in augmenting the release of pro-inflammatory cytokine IL-8 (show IL8 Proteins).
ZNF580 is a binding partner of Smad2 (show SMAD2 Proteins) and is involved in the signal transduction of the transforming growth factor-beta signalling pathway.
ZNF580 is a novel factor in the lipoprotein-dependent regulation of endothelial IL-8 (show IL8 Proteins) expression and monocyte arrest.
These results elucidate the important role that ZNF580 plays in the process of migration and proliferation of endothelial cells, which provides a foundation for a novel approach to regulate angiogenesis.
May be involved in transcriptional regulation.
LDL induced EC protein
, LDL-induced EC protein