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may act as a transcription factor [RGD, Feb 2006].. Additionally we are shipping Zinc Finger Protein 689 Proteins (3) and many more products for this protein.
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Cow (Bovine) Polyclonal ZNF689 Primary Antibody for WB - ABIN2778456
Silva, Hamamoto, Furukawa, Nakamura: TIPUH1 encodes a novel KRAB zinc-finger protein highly expressed in human hepatocellular carcinomas. in Oncogene 2006
The results indicate that ZNF689 blocks pro-apoptotic signaling by suppressing the Bak (show BAK1 Antibodies)/Bax (show BAX Antibodies)/Bid (show BID Antibodies) pathway, resulting in the progression of liver cancer and resistance to 5-FU. ZNF689 may be a promising chemotherapeutic target against liver cancer.
TIPUH1 conferred anchorage independent growth and its knockdown in HCCs (show HCCS Antibodies) resulted in their growth inhibition. Interacts with TIF1beta (show TRIM28 Antibodies), hnRNPU (show HNRNPU Antibodies), hnRNPF (show HNRNPF Antibodies), Nucleolin (show NCL Antibodies). May play a role in hepatocarcinogenesis by regulating transcription and/or RNA processing.
may act as a transcription factor
transcription-involved protein upregulated in HCC 1
, zinc finger protein HIT-39
, transcription factor HIT-39