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anti-Zinc Finger and BTB Domain Containing 7B (ZBTB7B) Antibodies

ZBTB7B encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. Additionally we are shipping Zinc Finger and BTB Domain Containing 7B Proteins (3) and Zinc Finger and BTB Domain Containing 7B Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZBTB7B 51043 O15156
ZBTB7B 295248  
ZBTB7B 22724 Q64321
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Top anti-Zinc Finger and BTB Domain Containing 7B Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-ZFP67 Antibody Titration: 1.0-2.0ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of ZBTB7B Antibody (Center) Pab (ABIN390349) in mouse brain tissue lysates (35 µg/lane). ZBTB7B (arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ZBTB7B antibody (Center)(ABIN390349), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ZBTB7B antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of ZBTB7B Antibody (Center) Pab in mouse brain tissue lysates (35ug/lane). ZBTB7B (arrow) was detected using the purified Pab (1:60 dilution). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of ZBTB7B Antibody (C-term) (ABIN1882155) in 293 cell line lysates (35 µg/lane). ZBTB7B (arrow) was detected using the purified Pab. Western blot analysis of ZBTB7B Antibody (C-term) (ABIN1882155) in 293 cell line lysates (35 µg/lane). ZBTB7B (arrow) was detected using the purified Pab. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ICC, IHC, ELISA, WB 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Mouse Un-conjugated IF, WB   100 μL Log in to see 10 to 11 Days
$464.29
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated EIA, IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details

ZBTB7B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) ,
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Top referenced anti-Zinc Finger and BTB Domain Containing 7B Antibodies

  1. Human Polyclonal ZBTB7B Primary Antibody for EIA, IHC (p) - ABIN358973 : Galéra, Musso, Ducy, Karsenty: c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin. in Proceedings of the National Academy of Sciences of the United States of America 1994 (PubMed)
    Show all 3 references for ABIN358973

  2. Human Monoclonal ZBTB7B Primary Antibody for ICC, IHC - ABIN1724728 : Ghayor, Herrouin, Chadjichristos, Ala-Kokko, Takigawa, Pujol, Galéra: Regulation of human COL2A1 gene expression in chondrocytes. Identification of C-Krox-responsive elements and modulation by phenotype alteration. in The Journal of biological chemistry 2000 (PubMed)
    Show all 3 references for ABIN1724728

  3. Human Monoclonal ZBTB7B Primary Antibody for IF, WB - ABIN2869481 : Egawa: Runx and ThPOK: a balancing act to regulate thymocyte lineage commitment. in Journal of cellular biochemistry 2009 (PubMed)
    Show all 3 references for ABIN2869481

  4. Human Polyclonal ZBTB7B Primary Antibody for IF, WB - ABIN1882155 : Matsumoto, Horiike, Ohshiro, Yamamoto, Sasaki, Tsutsumi, Kobayashi, Shimizu, Uchiyama, Kuroda, Nomura, Shimazaki, Taniwaki: Expression of master regulators of helper T-cell differentiation in peripheral T-cell lymphoma, not otherwise specified, by immunohistochemical analysis. in American journal of clinical pathology 2010 (PubMed)
    Show all 2 references for ABIN1882155

  5. Cow (Bovine) Polyclonal ZBTB7B Primary Antibody for IHC, WB - ABIN2777563 : Widom, Culic, Lee, Korn: Cloning and characterization of hcKrox, a transcriptional regulator of extracellular matrix gene expression. in Gene 1997 (PubMed)
    Show all 2 references for ABIN2777563

  6. Human Polyclonal ZBTB7B Primary Antibody for EIA, WB - ABIN400978 : He, He, Dave, Zhang, Hua, Nicolas, Xu, Roe, Kappes: The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. in Nature 2005 (PubMed)
    Show all 2 references for ABIN400978

More Antibodies against Zinc Finger and BTB Domain Containing 7B Interaction Partners

Human Zinc Finger and BTB Domain Containing 7B (ZBTB7B) interaction partners

  1. a novel pathway by which TIP60 (show KAT5 Antibodies) and ThPOK synergistically suppresses Eomes (show EOMES Antibodies) function and IFNgamma production, which could contribute to the regulation of inflammation.

  2. ThPOK may be considered a central regulator of the earliest events in the immune system during colorectal cancer development, decreasing the immune response against cancer cells.

  3. The distal regulatory element (DRE (show SUFUH Antibodies)) in the Thpok gene also functions as a transcriptional enhancer, with DNA sequences specifically responsible for thymic enhancer activity.

  4. ThPOK transgene stably represses CD8 (show CD8A Antibodies) gene expression through the deacetylation of Cd8 (show CD8A Antibodies) loci in CD4 (show CD4 Antibodies) cell lineage commitment.

  5. The p65 (show GORASP1 Antibodies) subunit of NF-kappaB (show NFKB1 Antibodies) inhibits COL1A1 (show COL1A1 Antibodies) gene transcription in human dermal and scleroderma fibroblasts through its recruitment on promoter by protein interaction with transcriptional activators (c-Krox, Sp1 (show PSG1 Antibodies), and Sp3 (show SP3 Antibodies)).

  6. impairment of Lck (show LCK Antibodies)-mediated CD4 (show CD4 Antibodies) coreceptor signaling by Nef is an important in vivo mechanism of HIV-1 pathogenesis

  7. Thymoma neoplastic epithelial cells can induce Th-POK expression in T-cell subsets similarly to the normal thymic epithelial cells. In addition, there was no significant difference in Runx3 (show RUNX3 Antibodies) expression in T-cell subsets between normal thymi and thymomas.

  8. These data suggest that the regulation of COL1A1 (show COL1A1 Antibodies) gene transcription in human dermal fibroblasts involves a complex machinery that implicates at least three transcription proteins, hc-Krox, Sp1 (show PSG1 Antibodies), and Sp3 (show SP3 Antibodies).

  9. Chondroitin sulphate and its derived hydrolytic fragments (CSf (show CSF2 Antibodies)) repress COL1A1 (show COL1A1 Antibodies) gene transcription through a -112/-61 bp sequence upstream the start site of transcription and imply hc-Krox and Sp1 (show PSG1 Antibodies) transcription factors.

  10. Runx and ThPOK role in mechanisms of lineage-specific gene regulation in the process of T-cell commitments[review]

Mouse (Murine) Zinc Finger and BTB Domain Containing 7B (ZBTB7B) interaction partners

  1. Runx3 (show RUNX3 Antibodies) is crucial for the phenotypic and functional changes observed in ThPok-deficient invariant natural killer T cells.

  2. present evidence that ectopic ThPOK expression gives rise to a preleukemic and self-perpetuating DN4 lymphoma precursor population

  3. Data indicate that transcription factors Thpok and LRF (show ZBTB7A Antibodies) redundantly maintain CD4 (show CD4 Antibodies)+ lineage integrity.

  4. induction of SOCS (show CISH Antibodies)-encoding genes is the main mechanism by which ThPOK imposes the CD4 (show CD4 Antibodies)(+) lineage fate in the thymus

  5. The role of TCF-1 (show HNF1A Antibodies) and LEF-1 (show LEF1 Antibodies) in the CD4 (show CD4 Antibodies)-versus-CD8 (show CD8A Antibodies) lineage 'choice' was mediated in part by direct positive regulation of the transcription factor Th-POK

  6. These findings imply that long-lasting T-cell receptor signals are needed to establish stable Thpok expression activity to commit to helper T-cell fate.

  7. Gata3 (show GATA3 Antibodies) promotes Cd4 (show CD4 Antibodies) expression in Thpok-deficient thymocytes.

  8. Data indicate that Valpha14 invariant natural killer T (Valpha14i NKT (show CTSL1 Antibodies)) cells from Th-POK-mutant helper deficient (hd/hd (show HTT Antibodies)) mice have increased transcripts of genes normally expressed by Th17 and NKT17 cells.

  9. ZBTB7B is a critical factor genetically predetermining the balance of effector subsets within the NKT (show CTSL1 Antibodies) cell population.

  10. Th-POK and Runx3 (show RUNX3 Antibodies) transcription factors are reciprocally involved in the control of G1-phase progression, on which they exert their functions dependently.

Zinc Finger and BTB Domain Containing 7B (ZBTB7B) Antigen Profile

Protein Summary

This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with ZBTB7B

  • zinc finger and BTB domain containing 7B (ZBTB7B) antibody
  • kruppel-related zinc finger protein hcKrox (zbtb7b) antibody
  • zinc finger and BTB domain containing 7B (Zbtb7b) antibody
  • zinc finger protein 317 (Zfp317) antibody
  • 4932416G03 antibody
  • c-Krox antibody
  • D230022C05Rik antibody
  • hcKROX antibody
  • KRAB9 antibody
  • MGC130914 antibody
  • mszf40 antibody
  • Thpok antibody
  • zbtb7b antibody
  • ZBTB15 antibody
  • ZFP-67 antibody
  • Zfp67 antibody
  • Zfp75 antibody
  • ZNF857B antibody

Protein level used designations for ZBTB7B

zinc finger and BTB domain containing 7B , kruppel-related zinc finger protein hcKrox , T-helper-inducing POZ/Krueppel-like factor , krueppel-related zinc finger protein cKrox , zinc finger and BTB domain containing 15 , zinc finger and BTB domain-containing protein 7B , zinc finger protein 67 homolog , zinc finger protein 857B , zinc finger protein Th-POK , zinc finger protein 67 , T helper-inducing POZ/Krueppel factor , Vzinc finger and BTB domain containing 7B , zfp-67 , zinc finger protein 75

GENE ID SPECIES
457353 Pan troglodytes
779199 Xenopus laevis
51043 Homo sapiens
295248 Rattus norvegicus
22724 Mus musculus
244713 Mus musculus
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