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Zinc Fingers and Homeoboxes 1 Proteins (ZHX1)

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. Additionally we are shipping ZHX1 Antibodies (44) and ZHX1 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ZHX1 11244 Q9UKY1
Mouse ZHX1 ZHX1 22770 P70121
Rat ZHX1 ZHX1 171159 Q8R515
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Top ZHX1 Proteins at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

ZHX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Zinc Fingers and Homeoboxes 1 (ZHX1) Interaction Partners

Human Zinc Fingers and Homeoboxes 1 (ZHX1) interaction partners

  1. High-quality solution NMR structures of three homeodomains from human proteins ALX4, ZHX1 and CASP8AP2 were solved.

  2. miR (show MLXIP Proteins)-199a-3p may function as a novel tumor promoter in gastric cancer and its oncogenic activity may involve the direct targeting and inhibition of ZHX1

  3. Low expression of ZHX1 may be responsible for hepatocarcinogenesis.

  4. Study showed that ZHX1 is SUMOylated by Ubc9 (show UBE2I Proteins) with SUMO1 (show SUMO1 Proteins) at the sites K159, K454, and K626 and that the SUMOylation of ZHX1 regulated the stability, ubiquitination and transcriptional activity of ZHX1.

  5. This study characterized features of ZHX-1 involved in nuclear localization, dimerization, and transcriptional activity, and mapped these domains.

  6. a search of ZHX1-interacting proteins using a yeast two-hybrid system

  7. ZHX1 enhanced the transcriptional repression mediated by DNMT3B (show DNMT3B Proteins) when DNMT3B (show DNMT3B Proteins) is directly targeted to DNA. These results showed for the first the direct linkage between DNMT (show DNMT1 Proteins) and zinc-fingers homeoboxes protein, leading to enhanced gene silencing by DNMT3B (show DNMT3B Proteins)

  8. structure of the tandem zinc-finger region of human ZHX1

Mouse (Murine) Zinc Fingers and Homeoboxes 1 (ZHX1) interaction partners

ZHX1 Protein Profile

Protein Summary

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 8 open reading frame 76 (C8orf76) gene.

Gene names and symbols associated with ZHX1

  • zinc fingers and homeoboxes 1 (ZHX1)
  • zinc fingers and homeoboxes 1 (zhx1)
  • zinc fingers and homeoboxes 1 (Zhx1)
  • 3110006I21Rik protein
  • mKIAA4149 protein
  • ZHX1 protein

Protein level used designations for ZHX1

zinc finger and homeodomain protein 1 , zinc fingers and homeoboxes 1 , zinc fingers and homeoboxes protein 1 , zinc fingers and homeobox 1 , zinc-fingers and homeoboxes 1 , Zinc fingers and homeoboxes protein 1

GENE ID SPECIES
100442425 Pongo abelii
420347 Gallus gallus
475089 Canis lupus familiaris
704254 Macaca mulatta
782847 Bos taurus
100126068 Xenopus (Silurana) tropicalis
100558335 Anolis carolinensis
11244 Homo sapiens
22770 Mus musculus
171159 Rattus norvegicus
100984802 Pan paniscus
464368 Pan troglodytes
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