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anti-Zyxin (ZYX) Antibodies

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Additionally we are shipping Zyxin Proteins (9) and Zyxin Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZYX 7791 Q15942
ZYX 22793 Q62523
ZYX 114636  
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Top anti-Zyxin Antibodies at antibodies-online.com

Showing 10 out of 86 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells treated with paclitaxel 1uM 24h, using Zyxin (Phospho-Ser142) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ZYX Antibody Titration: 1.25ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate Sample Type: HeLa whole cell lysatePrimary Dilution: 1:200 100 μL Log in to see 2 to 3 Days
$229.00
Details
Dog Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Chicken Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of Zyxin on SL-29 cell lysate. Lane 1: 1:2500, lane 2: 1:5000, lane 3: 1:10000 dilution of anti-Zyxin. Immunofluorescent staining of chick fibroblasts. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Mouse Un-conjugated ICC, IP, WB 100 μg Log in to see 5 to 6 Days
$444.68
Details
Human Mouse Un-conjugated WB Western blot analysis of ZYX over-expressed 293 cell line, cotransfected with ZYX Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of ZYX expression in transfected 293T cell line by ZYX monoclonal antibody (M01), clone 2C10-4A7. Lane 1: ZYX transfected lysate(61.3 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Human Adipose: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$595.83
Details

ZYX Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-Zyxin Antibodies

  1. Human Monoclonal ZYX Primary Antibody for ICC, IP - ABIN1742558 : Mori, Nakagami, Koibuchi, Miura, Takami, Koriyama, Hayashi, Sabe, Mochizuki, Morishita, Kaneda: Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis. in Molecular biology of the cell 2009 (PubMed)
    Show all 10 references for ABIN1742558

  2. Human Monoclonal ZYX Primary Antibody for WB - ABIN395405 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN395405

  3. Chicken Monoclonal ZYX Primary Antibody for IF, IP - ABIN968016 : Drees, Friederich, Fradelizi, Louvard, Beckerle, Golsteyn: Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins. in The Journal of biological chemistry 2000 (PubMed)
    Show all 5 references for ABIN968016

  4. Cow (Bovine) Polyclonal ZYX Primary Antibody for WB - ABIN2775766 : Li, Zhuang, Trueb: Zyxin interacts with the SH3 domains of the cytoskeletal proteins LIM-nebulette and Lasp-1. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN2775766

  5. Human Polyclonal ZYX Primary Antibody for ELISA, WB - ABIN1532180 : Hillier, Fulton, Fulton, Graves, Pepin, Wagner-McPherson, Layman, Maas, Jaeger, Walker, Wylie, Sekhon, Becker, OLaughlin, Schaller, Fewell, Delehaunty, Miner, Nash, Cordes, Du, Sun, Edwards et al.: The DNA sequence of human chromosome 7. ... in Nature 2003 (PubMed)

  6. Cow (Bovine) Polyclonal ZYX Primary Antibody for WB - ABIN2775767 : Martynova, Eroshkin, Ermolina, Ermakova, Korotaeva, Smurova, Gyoeva, Zaraisky: The LIM-domain protein Zyxin binds the homeodomain factor Xanf1/Hesx1 and modulates its activity in the anterior neural plate of Xenopus laevis embryo. in Developmental dynamics : an official publication of the American Association of Anatomists 2008 (PubMed)

More Antibodies against Zyxin Interaction Partners

Caenorhabditis elegans (C. elegans) Zyxin (ZYX) interaction partners

  1. ZYX-1 is a conserved LIM (show PDLIM5 Antibodies) domain-containing focal adhesion protein that regulates synapse maintenance in Caenorhabditis elegans

  2. The zyx-1 gene encodes two different isoforms, ZYX-1a and ZYX-1b, which exhibit different roles in dystrophin (show DMD Antibodies)-dependent muscle degeneration in C. elegans

  3. DYC-1 interacts with ZYX-1, the homologue of the vertebrate focal adhesion LIM domain protein (show PDLIM7 Antibodies) zyxin.

Fruit Fly (Drosophila melanogaster) Zyxin (ZYX) interaction partners

  1. results show that Zyxin is a functional antagonist of Expanded in growth control

  2. The motor domain of DmMyo20 could specifically bind to actin (show ACTB Antibodies) filaments in an ATP-independent manner and enhance the interaction between actin (show ACTB Antibodies) filaments and Zyx102, a downstream component of DmMyo20 in the Fat signaling pathway.

  3. Through epistasis tests, the requirement for Zyx is positioned within the Fat branch of Hippo signaling, downstream of Fat and Dco (show CSNK1E Antibodies), and upstream of the Yorkie (show YAP1 Antibodies) kinase Warts.

  4. Reduction of Zyx102 protein levels using RNA-interference results in lethality at the pharate adult stage.

Human Zyxin (ZYX) interaction partners

  1. VASP (show VASP Antibodies), zyxin and TES (show TES Antibodies) are tension-dependent members of focal adherens junctions independent of the alpha-catenin (show CTNNA1 Antibodies)-vinculin (show VCL Antibodies) module.

  2. Zyxin binding to Ptc2 (show PTCH2 Antibodies) is due to the interaction of Zyxin 2nd LIM (show PDLIM5 Antibodies)-domain (530-590 aa) with the under-membrane region of the cytoplasmic C-terminus of Ptc2 (show PTCH2 Antibodies) (1159-1412 aa).

  3. ZYX gene may be aging-related gene and involved in Osteoporosis.

  4. Matrix density alters zyxin phosphorylation, which limits peripheral process formation and extension in endothelial cells invading 3D collagen matrices.

  5. Zyxin, which is thought to be essential for tight cell-to-cell junctions, decreased 1.8-fold in TNF-alpha (show TNF Antibodies)-treated human brain microvascular endothelial cells.

  6. Integrin-beta5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor beta.

  7. Zyxin is a novel target for beta-amyloid peptide (show APP Antibodies) activities in Alzheimer's disease.

  8. Zyxin is suggested to promote growth, migration and invasiveness of fibroblastic type oral squamous cell carcinoma cells by upregulating Rac1 and Cdc42 (show CDC42 Antibodies).

  9. A stretch-induced signaling pathway in vascular cells leads to the activation of zyxin, a cytoskeletal protein (show ACTN1 Antibodies) specifically involved in transducing mechanical stimuli.

  10. RA-induced cancer cell cytotoxicity was significantly impaired by Zyxin or PTOV1 (show PTOV1 Antibodies). Overall, our findings suggest that Zyxin and PTOV1 (show PTOV1 Antibodies) should be considered as critical determinants in cancer therapy with retinoids

Mouse (Murine) Zyxin (ZYX) interaction partners

  1. zyxin influences focal adhesion dynamics, that it recruits Tes (show TES Antibodies) and that this interaction is functional in regulating cell spreading.

  2. Zyxin contributes to the migratory and invasive phenotype evoked by Tead2 (show TEAD2 Antibodies).

  3. Integrin-beta5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor beta.

  4. paxillin (show PXN Antibodies) and zyxin are LIM (show PDLIM5 Antibodies)-domain adaptor proteins that are recruited to stress fiber strain sites

  5. Zyxin regulates migration of renal epithelial cells through activation of hepatocyte nuclear factor-1beta.

  6. Zyxin is a transforming growth factor-beta (TGF-beta)/Smad3 (show SMAD3 Antibodies) target gene that regulates lung cancer cell motility via integrin alpha5beta1.

  7. a bipartite mechanism for stretch-induced actin remodeling involves mechanosensitive targeting of zyxin to actin stress fibers and localized recruitment of actin regulatory machinery

  8. Mice that lack zyxin function are viable and fertile and display no obvious histological abnormalities in any of the organs examined.Specifically, we evaluated blood platelet function, nervous system development, and skin architecture

  9. LIM-nebulette (show NEBL Antibodies), Lasp-1 (show LASP1 Antibodies), and zyxin may play an important role in the organization of focal adhesions

  10. Cooperates with Ena, vasodilator-stimulated phosphoprotein, and caldesmon to influence integrin-dependent cell motility and actin stress fiber remodeling.

Xenopus laevis Zyxin (ZYX) interaction partners

  1. Zyxin binding to Ptc2 (show PTCH2 Antibodies) is due to the interaction of Zyxin 2nd LIM (show PDLIM5 Antibodies)-domain (530-590 aa) with the under-membrane region of the cytoplasmic C-terminus of Ptc2 (show PTCH2 Antibodies) (1159-1412 aa).

  2. Zyxin inhibits Shh (show SHH Antibodies) signaling during the CNS patterning in Xenopus laevis through interaction with Gli1 (show GLI1 Antibodies)

  3. These results are consistent with a possible role of Zyxin as a negative modulator of Xanf1 transcriptional repressing activity.

  4. binding of the LIM2 domain of zyxin with the Engrailed Homology 1 repressor domain of Xanf1 is responsible for the interaction of these proteins.

Zyxin (ZYX) Antigen Profile

Protein Summary

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

Gene names and symbols associated with anti-Zyxin (ZYX) Antibodies

  • ZYXin (zyx-1) antibody
  • Zyxin (Zyx) antibody
  • zyxin (zyx) antibody
  • zyxin (ZYX) antibody
  • Zyxin (zyx) antibody
  • zyxin (EDI_201420) antibody
  • zyxin (LOC100219276) antibody
  • zyxin (Zyx) antibody
  • zyxin (LOC100049724) antibody
  • 9530098H06Rik antibody
  • BcDNA:LD06023 antibody
  • CG32018 antibody
  • DLim-1 antibody
  • Dmel\\CG32018 antibody
  • DmLIM-1 antibody
  • ESP-2 antibody
  • HED-2 antibody
  • lim antibody
  • Lim102EF antibody
  • MGC145270 antibody
  • R75157 antibody
  • zgc:171680 antibody
  • zyx antibody
  • zyx102 antibody
  • Zyx102EF antibody
  • zyxin antibody

Protein level used designations for anti-Zyxin (ZYX) Antibodies

ZYXin family member (zyx-1) , CG32018-PA , CG32018-PB , CG32018-PG , CG32018-PH , Zyx-PA , Zyx-PB , Zyx-PG , Zyx-PH , Zyx102EF , zyxin , hypothetical protein LOC779718 , zyxin-2

GENE ID SPECIES
174951 Caenorhabditis elegans
317824 Drosophila melanogaster
564246 Danio rerio
706407 Macaca mulatta
779718 Xenopus (Silurana) tropicalis
5914189 Entamoeba dispar SAW760
100011992 Monodelphis domestica
100219276 Taeniopygia guttata
7791 Homo sapiens
768226 Bos taurus
22793 Mus musculus
114636 Rattus norvegicus
482736 Canis lupus familiaris
100524720 Sus scrofa
418300 Gallus gallus
100049724 Xenopus laevis
Selected quality suppliers for anti-Zyxin (ZYX) Antibodies
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