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alpha 1, 4-Galactosyltransferase Proteins (A4GALT)

The protein encoded by A4GALT catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. Additionally we are shipping A4GALT Antibodies (46) and A4GALT Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
A4GALT 53947 Q9NPC4
A4GALT 239559 Q67BJ4
Rat A4GALT A4GALT 63888 Q9JI93
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Top A4GALT Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

A4GALT Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for alpha 1, 4-Galactosyltransferase (A4GALT) Interaction Partners

Human alpha 1, 4-Galactosyltransferase (A4GALT) interaction partners

  1. Mutation in the A4GALT gene is associated with rare p phenotype in P1Pk blood group (show DARC Proteins) system.

  2. The results of this investigation demonstrate a consistent association of A4GALT SNPs rs2143918 and rs5751348 with the P1/P2 phenotypes and suggest that SNP rs5751348 may lead to allelic variations in A4GALT gene expression

  3. these data elucidate a new explanation underlying the p phenotype, implicating the deleted regions of A4GALT as crucial for P1 and P(k) synthesis, possibly due to loss of binding sites for erythroid transcription factors.

  4. P1-decorated PSGL-1 (show SELPLG Proteins)/mIgG2b bound with high avidity to both Stx1 (show STX1A Proteins) and Stx2 (show STX2 Proteins), and as such constitutes a potential therapeutic inhibitor of these toxins.

  5. Results suggest that the C631G mutation alters the acceptor specificity of Gb3/CD77 synthase, rendering it able to catalyze synthesis of the Gal (show GAL Proteins)(alpha1-4)Gal (show GAL Proteins) and Gal (show GAL Proteins)(alpha1-4)GalNAc moieties.

  6. Increased globotriaosylceramide levels are detected in a transgenic mouse expressing human alpha1,4-galactosyltransferase (show GGTA1 Proteins) in a mouse model for treating Fabry disease.

  7. Data showed that GRINA-C was associated with Gb3 synthase, and may demonstrate a new type of posttranscriptional regulation of glycosyltransferases.

  8. of A4GALT mRNA in cultured human bone marrow cells revealed novel transcripts containing only the noncoding exon 1 and a sequence (here termed exon 2a) from intron 1.

  9. We established by quantitative real-time PCR that both fresh colonic epithelial sections and HCT-8 cells express Gb3 synthase mRNA and the alternate Shiga toxin receptor globotetraosylceramide.

  10. The P blood group (show DARC Proteins) phenotype is due to several disctint nonfunctional alleles of A4GALT without any predominant allele.

Mouse (Murine) alpha 1, 4-Galactosyltransferase (A4GALT) interaction partners

A4GALT Protein Profile

Protein Summary

The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor.

Gene names and symbols associated with A4GALT

  • alpha 1,4-galactosyltransferase (A4GALT)
  • alpha 1,4-galactosyltransferase (A4galt)
  • A4GALT1 protein
  • A14GALT protein
  • Gb3 protein
  • Gb3S protein
  • P(k) protein
  • P1 protein
  • P1PK protein
  • PK protein

Protein level used designations for A4GALT

CD77 synthase , GB3 synthase , P blood group (P one antigen) , P(k) antigen synthase , P1/Pk synthase , UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase , alpha-1,4-N-acetylglucosaminyltransferase , alpha4Gal-T1 , globotriaosylceramide synthase , lactosylceramide 4-alpha-galactosyltransferase , Gb3 synthase , Gb3/CD77 synthase , alpha-1,4-galactosyltransferase , alpha 1,4-galactosyltransferase (globotriaosylceramide synthase)

GENE ID SPECIES
53947 Homo sapiens
239559 Mus musculus
63888 Rattus norvegicus
418223 Gallus gallus
481222 Canis lupus familiaris
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