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alpha Hemoglobin Stabilizing Protein (aHSP) ELISA Kits

Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Additionally we are shipping aHSP Antibodies (38) and aHSP Proteins (17) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
aHSP 51327 Q9NZD4
aHSP 170812 Q9CY02
Anti-Rat aHSP aHSP 293522  
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Top aHSP ELISA Kits at antibodies-online.com

Showing 8 out of 14 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.055 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$663.16
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Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
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Chicken
  96 Tests Log in to see 8 to 9 Days
$770.00
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Monkey
  96 Tests Log in to see 8 to 9 Days
$770.00
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Guinea Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
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Rabbit
  96 Tests Log in to see 8 to 9 Days
$770.00
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Mouse
0.312-20 ng/mL   96 Tests Log in to see 11 to 13 Days
$875.60
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Cow
  96 Tests Log in to see 11 to 13 Days
$1,029.60
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More ELISA Kits for aHSP Interaction Partners

Human alpha Hemoglobin Stabilizing Protein (aHSP) interaction partners

  1. AHSP is predominantly expressed in erythroid precursors in bone marrow biopsy specimens from patients with hematologic malignancies.

  2. AHSP expression was higher in patients with sickle cell anemia versus thalassemia, with no significant difference between BTM and BTI. Expression was higher in patients with NTDT and on hydroxyurea therapy.

  3. In maturing RBC (show CACNA1C ELISA Kits) progenitors AHSP bind to free alpha-globin (show HBA1 ELISA Kits) chains to increase the HbA (show SCN2A ELISA Kits) production. (Review)

  4. analysis showed binding of STAT3 (show STAT3 ELISA Kits) to AHSP promoter and binding was significantly augmented with IL6 (show IL6 ELISA Kits) stimulation and upon alpha-globin (show HBA1 ELISA Kits) overexpression

  5. The relationship between AHSP gene expression, disease severity, and the beta/alpha globin (show HBA1 ELISA Kits) mRNA ratio was studied among different homozygote beta-thalassemia patients.

  6. alpha-Hemoglobin-stabilizing protein (AHSP) perturbs the proximal heme pocket of oxy (show GCG ELISA Kits)-alpha-hemoglobin and weakens the iron-oxygen bond.

  7. alpha-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of alpha-subunits of human HbA (show SCN2A ELISA Kits) with hydrogen peroxide.

  8. AHSP acts as a molecular chaperone (show HSP90AA1 ELISA Kits) by rapidly binding and stabilizing met-alpha hemichrome folding intermediates

  9. AHSP could be a secondary compensatory mechanism in red blood cells to counterbalance the excess of alpha-globin (show HBA1 ELISA Kits) chains in HbE (show HBe1 ELISA Kits)/beta-thalassaemia individuals.

  10. NF-E2 (show NFE2 ELISA Kits) may play an important role in AHSP gene regulation, providing new insights into the molecular mechanisms underlying the erythroid-specific expression of AHSP as well as new possibilities for beta-thalassemia treatment

Mouse (Murine) alpha Hemoglobin Stabilizing Protein (aHSP) interaction partners

  1. role of alpha-hemoglobin stabilizing protein in hemoglobin assembly

  2. Endogenous AHSP is not limiting for alpha-globin (show HBA-A1 ELISA Kits) detoxification in beta-thalassemic mice.

  3. activin A (show INHBA ELISA Kits) does not appear to affect the exocrine or endocrine components of the pancreas, but promotes differentiation of pancreatic tissue into intestine via a Shh (show SHH ELISA Kits)-dependent mechanism

  4. Loss of AHSP impairs erythropoiesis and exacerbates beta-thalassemia.

  5. These results support the hypothesis that EKLF (show KLF1 ELISA Kits) acts as a transcription factor and a chromatin modulator for the AHSP and beta-globin (show HBB ELISA Kits) genes and indicate that EKLF (show KLF1 ELISA Kits) may play similar roles for other erythroid genes.

  6. developmental stage- and differentiation state-specific regulation of the nuclear transport of EKLF (show KLF1 ELISA Kits) might be one of the steps necessary for the switch-on of the mammalian adult beta globin (show HBB ELISA Kits) gene transcription

  7. AHSP also acts as a molecular chaperone to stabilize nascent alpha-globin for hemoglobin A assembly

  8. The expression of AHSP in a subclone of murine erythroleukemia cells in relationship to prion protein (show PRNP ELISA Kits) on the cell surface is reported.

aHSP Antigen Profile

Antigen Summary

Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation (By similarity).

Gene names and symbols associated with aHSP

  • alpha hemoglobin stabilizing protein (AHSP) antibody
  • erythroid associated factor (LOC100340962) antibody
  • alpha hemoglobin stabilizing protein (Ahsp) antibody
  • alpha-hemoglobin-stabilizing protein-like (LOC100620111) antibody
  • AHSP antibody
  • EDRF antibody
  • Eraf antibody

Protein level used designations for aHSP

alpha hemoglobin stabilizing protein , erythroid associated factor , alpha hemoglobin stabilising protein , alpha-hemoglobin-stabilizing protein , erythroid differentiation associated factor , erythroid differentiation-related factor , erythroid-associated factor

GENE ID SPECIES
454073 Pan troglodytes
714392 Macaca mulatta
100127218 Ovis aries
100340962 Oryctolagus cuniculus
51327 Homo sapiens
170812 Mus musculus
338381 Bos taurus
293522 Rattus norvegicus
100712877 Cavia porcellus
100620111 Sus scrofa
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