alpha-2-Macroglobulin-Like 1 Proteins (A2ML1)

A2ML1 encodes a member of the alpha-macroglobulin superfamily. Additionally we are shipping A2ML1 Antibodies (28) and A2ML1 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID
A2ML1 144568
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Top A2ML1 Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days

A2ML1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,

More Proteins for alpha-2-Macroglobulin-Like 1 (A2ML1) Interaction Partners

Human alpha-2-Macroglobulin-Like 1 (A2ML1) interaction partners

  1. The indigenous Filipino population has a ~50% prevalence of otitis media. A2ML1 genotype is the primary risk factor for otitis media and main determinant of disease progression, although age, the middle ear microbiome, and social clusters might modulate the effect of the A2ML1 genotype.

  2. A2ML1-related otitis media susceptibility may be mediated by changes in the middle ear microbiome.

  3. Studies support a role for alpha-2-macroglobulin-like 1 protein (A2ML1) in the pathophysiology of otitis media.

  4. our results provide evidence that mutations in A2ML1 are a cause of Noonan-like syndrome, with a variable phenotype ranging from severe to very mild.

  5. a new class of target antigens in a paraneoplastic autoimmune multiorgan syndrome

  6. alpha2ML1 binding to the low density lipoprotein receptor-related protein 1 (LRP1 (show LRP1 Proteins)) reveals a new role for LRP1 (show LRP1 Proteins) in the human epidermis

A2ML1 Protein Profile

Protein Summary

This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein acts as an inhibitor for several proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP\; PMID: 20805888). Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with A2ML1

  • alpha-2-macroglobulin-like 1 (A2ML1)
  • CPAMD9 protein

Protein level used designations for A2ML1

C3 and PZP-like, alpha-2-macroglobulin domain containing 9 , alpha-2-macroglobulin-like protein 1

144568 Homo sapiens
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