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A2ML1 encodes a member of the alpha-macroglobulin superfamily. Additionally we are shipping A2ML1 Antibodies (28) and A2ML1 Kits (7) and many more products for this protein.
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The indigenous Filipino population has a ~50% prevalence of otitis media. A2ML1 genotype is the primary risk factor for otitis media and main determinant of disease progression, although age, the middle ear microbiome, and social clusters might modulate the effect of the A2ML1 genotype.
A2ML1-related otitis media susceptibility may be mediated by changes in the middle ear microbiome.
Studies support a role for alpha-2-macroglobulin-like 1 protein (A2ML1) in the pathophysiology of otitis media.
our results provide evidence that mutations in A2ML1 are a cause of Noonan-like syndrome, with a variable phenotype ranging from severe to very mild.
a new class of target antigens in a paraneoplastic autoimmune multiorgan syndrome
alpha2ML1 binding to the low density lipoprotein receptor-related protein 1 (LRP1 (show LRP1 Proteins)) reveals a new role for LRP1 (show LRP1 Proteins) in the human epidermis
This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein acts as an inhibitor for several proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP\; PMID: 20805888). Alternative splicing results in multiple transcript variants.
C3 and PZP-like, alpha-2-macroglobulin domain containing 9
, alpha-2-macroglobulin-like protein 1