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beta-1,4-N-Acetyl-Galactosaminyl Transferase 2 Proteins (B4GALNT2)

B4GALNT2 catalyzes the last step in the biosynthesis of the human Sd(a) antigen through the addition of an N-acetylgalactosamine residue via a beta-1,4 linkage to a subterminal galactose residue substituted with an alpha-2,3-linked sialic acid. Additionally we are shipping B4GALNT2 Antibodies (7) and B4GALNT2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
B4GALNT2 124872 Q8NHY0
B4GALNT2 14422 Q09199
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Top B4GALNT2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details

B4GALNT2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
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Mouse (Murine) ,
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More Proteins for beta-1,4-N-Acetyl-Galactosaminyl Transferase 2 (B4GALNT2) Interaction Partners

Human beta-1,4-N-Acetyl-Galactosaminyl Transferase 2 (B4GALNT2) interaction partners

  1. In normal colon samples a significant relationship between sLe(x) expression and the ratio between FUT6 (show FUT6 Proteins)/B4GALNT2 activities exists, demonstrating for the first time a role for B4GALNT2 in sLe(x) inhibition in vivo.

  2. molecular cloning; cDNA predicts a 566 aa protein showing 66.6% and 39% identity with mouse CT beta4GalNAc-T and human GM2/GD2 synthase (show B4GALNT1 Proteins)

  3. A putative CpG island encompassing the promoter and exon 1 regions in the human Sd(a) beta4GalNAcT (show CSGALNACT1 Proteins)-II gene was identified.

  4. Epigenetic changes in a group of glycosyltransferases including B4GALNT2 and ST3GAL6 (show ST3GAL6 Proteins) represent a malignant phenotype of gastric cancer caused by silencing of the activity of these enzymes

Mouse (Murine) beta-1,4-N-Acetyl-Galactosaminyl Transferase 2 (B4GALNT2) interaction partners

  1. Overexpression of Galgt2 failed to inhibit skeletal muscle pathology in dystroglycan-deficient muscles

  2. These data support a critical role for B4galnt2 in gastrointestinal infections

  3. Galgt2 is required for postsynaptic expression of the CT carbohydrate at the neuromuscular junction.

  4. We describe changes that result from overexpression of Galgt2, a normally synaptic muscle glycosyltransferase (show GTDC2 Proteins) that can modify alpha dystroglycan and inhibit the development of muscular dystrophy when it is overexpressed.

  5. Study describes detailed characterization of mouse gastrointestinal bacterial communities in 7 distinct locations from the duodenum to the colon and provide evidence for a significant effect of B4galnt2 expression on intestinal bacterial populations.

  6. Data suggest that B4GALNT2 and Sd(a) antigen are essential for embryo implantation.

  7. Expression of B4galnt2 in pregnant mice is regulated by progesterone. The naturally occurring up-regulation of B4galnt2 during pregnancy contributes to normal embryo implantation.

  8. we show that overexpression of the cytotoxic T cell (CT) GalNAc transferase (Galgt2) is effective in inhibiting the development of muscle pathology in the dy(W) mouse model of MDC1A

  9. These experiments demonstrate that Galgt2 can control growth by modulating the expression of myostatin (show MSTN Proteins) and myostatin (show MSTN Proteins) inhibitors during particular periods of muscle development.

  10. low VWF (show VWF Proteins) levels may represent a fitness cost that is offset by a yet unknown benefit of the B4galnt2 tissue-specific switch.

B4GALNT2 Protein Profile

Protein Summary

B4GALNT2 catalyzes the last step in the biosynthesis of the human Sd(a) antigen through the addition of an N-acetylgalactosamine residue via a beta-1,4 linkage to a subterminal galactose residue substituted with an alpha-2,3-linked sialic acid. B4GALNT2 also catalyzes the last step in the biosynthesis of the Cad antigen (Montiel et al., 2003

Gene names and symbols associated with B4GALNT2

  • beta-1,4-N-acetyl-galactosaminyl transferase 2 (B4GALNT2)
  • beta-1,4-N-acetyl-galactosaminyl transferase 2 (B4galnt2)
  • AI593864 protein
  • B4GALT protein
  • Dlb-1 protein
  • Dlb1 protein
  • Galg2 protein
  • Galgt2 protein
  • Ggm3 protein
  • Igf2bp1 protein

Protein level used designations for B4GALNT2

UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase , UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase , beta 1,4 N-acetylgalactosaminyltransferase/betal,4 GalNAcT/Sda-GalNAcT , beta-1,4 N-acetylgalactosaminyltransferase 2 , beta-4-N-acetylgalactosaminyltransferase , sd(a) beta-1,4-GalNAc transferase , sda beta-1,4-GalNAc transferase , CT-Gal NAc transferase , N-acetylgalactosaminyltransferase , UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosyl-N-acetylglucosaminylpolypeptide-beta-1, 4-N-acetylgalactosaminyltransferase , dolichos lectin binding 1

GENE ID SPECIES
124872 Homo sapiens
14422 Mus musculus
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