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gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 Proteins (GABRA1)

GABRA1 encodes a gamma-aminobutyric acid (GABA) receptor. Additionally we are shipping gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 Antibodies (130) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GABRA1 2554 P14867
Rat GABRA1 GABRA1 29705 P62813
GABRA1 14394 P62812
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Top gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

GABRA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
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More Proteins for gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) Interaction Partners

Human gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) interaction partners

  1. GABRA1 missense mutations were linked to early onset epileptic encephalopathies, including Ohtahara syndrome and West syndrome.

  2. Polymorphism rs4263535 in GABRA1 intron 4 was associated with deeper sedation by intravenous midazolam.

  3. Putative GABAA (show GABRg1 Proteins) and ASIC1a (show ACCN2 Proteins) channels functionally interact with each other, possibly via an inter-molecular association by forming a novel protein complex.

  4. The role of the N-terminal extension and putative alpha-helix in heteromeric alpha1beta2gamma2 GABAA (show GABRg1 Proteins) receptors was most prominent in the alpha1 subunit. Deletion reduced the number of functional receptors.

  5. These results suggest that ARG1 (show ARG1 Proteins) and GABA influence both neural development and neuroblastoma (show ARHGEF16 Proteins) and that benzodiazepines in clinical use may have potential applications for neuroblastoma (show ARHGEF16 Proteins) therapy.

  6. Tobacco smoking, but not nicotine interferes with GABAA (show GABRg1 Proteins) receptor neuroadaptations during prolonged alcohol withdrawal.

  7. Propofol, AziPm, and o-PD Inhibit [3H]Azietomidate and R-[3H]mTFD-MPAB Photolabeling of alpha1beta3 GABAAR (show GABRG2 Proteins).

  8. This study demonstrates altered patterns of N-glycosylation of GABRA1 in the temporal lobe in schizophrenia.

  9. GABRA1 and STXBP1 (show STXBP1 Proteins) make a significant contribution to Dravet syndrome

  10. Genome-wide association studies identify GABRA1 mutation releated to juvenile myoclonic epilepsy.

Cow (Bovine) gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) interaction partners

  1. GAPDH (show GAPDH Proteins) directly phosphorylates the long intracellular loop of GABA(A) receptor alpha1 subunit at identified serine and threonine residues. GAPDH (show GAPDH Proteins) and the alpha1 subunit were found to be colocalized at the neuronal plasma membrane.

  2. Numerous classes of general anesthetics inhibit etomidate binding to gamma-aminobutyric acid type A (GABAA (show GABRg1 Proteins)) receptors

Mouse (Murine) gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) interaction partners

  1. the identity and location of distinct GABAAR (show GABRG2 Proteins) subunits within the cellular networks of the mouse dorsal raphe nucleus and that stress impacts on the expression levels of particular subunits at the gene and protein level

  2. This study demonstrated that Adolescent-onset GABAA (show GABRg1 Proteins) alpha1 silencing regulates reward-related decision making in mice.

  3. Enduring loss of tonic but not phasic GABAAR (show GABRG2 Proteins) currents critically contributes to the prolonged amygdala disinhibition subsequent to chronic stress.

  4. these findings suggest that gephyrin (show GPHN Proteins) may be a key factor in BDNF (show BDNF Proteins)-dependent GABAAR (show GABRG2 Proteins) regulation in the amygdala.

  5. Gabra1 receptors are expressed in the ventral thalamus in an absence epilepsy model.

  6. The effects of heterozygous knock-out of GABAAR (show GABRG2 Proteins) alpha1 on the expression and physiology of GABAARs in the mouse cortex, were determined.

  7. Cell-type specifici deletion of Gaba(a)alpha1 in corticotropin-releasing factor (show CRH Proteins)-containing neurons enhances anxiety and disrupts fear extinction.

  8. Further support for an interaction between GABA(A) and metabotropic glutamate (show GRIN1 Proteins) receptor subtype(mGlu)4 receptors is obtained in the mGlu4 (show GRM4 Proteins) knockout mouse which displayed reduced binding of the GABA(A)receptor in cerebellar parallel fibers.

  9. These data show that enhanced, rather than compromised, GABA(A) receptor-mediated inhibition occurs in cortico-thalamic networks of SSADH (show ALDH5A1 Proteins)(-/-) mice.

  10. Since DOR over-expression increases cortical tolerance to hypoxia, an increase in GABA receptors expression (an energy-costing process) may not be necessary in the cortex with DOR over-expression

gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) Protein Profile

Protein Summary

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.

Gene names and symbols associated with GABRA1

  • gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1)
  • gamma-aminobutyric acid (GABA) A receptor, alpha 1 (Gabra1)
  • gamma-aminobutyric acid (GABA) A receptor, alpha 1 (gabra1)
  • gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 (Gabra1)
  • gamma-aminobutyric acid A receptor subunit alpha-1 (gabra1)
  • ECA4 protein
  • EJM protein
  • EJM5 protein
  • Gabra-1 protein
  • zgc:153566 protein

Protein level used designations for GABRA1

GABA(A) receptor subunit alpha-1 , GABA(A) receptor, alpha 1 , gamma-aminobutyric acid receptor subunit alpha-1 , gamma-aminobutyric acid A receptor, alpha 1 , gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1 , gamma-aminobutyric acid A receptor, alpha 1 , gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 , GABAA alpha 1

GENE ID SPECIES
2554 Homo sapiens
29705 Rattus norvegicus
489143 Canis lupus familiaris
780973 Bos taurus
374214 Gallus gallus
768183 Danio rerio
100172731 Pongo abelii
14394 Mus musculus
100653509 Xenopus laevis
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