GABRA1 Products
(gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
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This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
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Featured GABRA1 Categories
GABRA1 Antibodies
High quality antibodies with extensive validation data.
GABRA1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GABRA1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, ICC, IF
Validations
- (4)
Cat. No.
ABIN2485717
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, ICC, IF, AA
Validations
- (4)
Cat. No.
ABIN863138
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, ICC, IF
Validations
- (4)
Cat. No.
ABIN2485730
Quantity
100 μg
Datasheet
Datasheet
Recommended GABRA1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6228560
Quantity
96 tests
Datasheet
Datasheet
Recommended GABRA1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1354645
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123050
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3080444
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GABRA1 products
: "Corticotropin-Releasing Factor Receptor-1 Neurons in the Lateral Amygdala Display Selective Sensitivity to Acute and Chronic Ethanol Exposure." in: eNeuro, Vol. 7, Issue 2, (2020) (PubMed).: "Strain-specific programming of prenatal ethanol exposure across generations." in: Alcohol (Fayetteville, N.Y.), Vol. 60, pp. 191-199, (2017) (PubMed).
: "α2 Subunit-Containing GABAA Receptor Subtypes Are Upregulated and Contribute to Alcohol-Induced Functional Plasticity in the Rat Hippocampus." in: Molecular pharmacology, Vol. 92, Issue 2, pp. 101-112, (2017) (PubMed).
: "How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs." in: Neuron, Vol. 91, Issue 4, pp. 792-807, (2016) (PubMed).
: "Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9526-39, (2016) (PubMed).
: "Role of microRNA-4458 in patients with non-small-cell lung cancer." in: Oncology letters, Vol. 12, Issue 5, pp. 3958-3966, (2016) (PubMed).
: "The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration." in: Nature neuroscience, Vol. 18, Issue 7, pp. 988-96, (2015) (PubMed).
: "The developmental evolution of the seizure phenotype and cortical inhibition in mouse models of juvenile myoclonic epilepsy." in: Neurobiology of disease, Vol. 82, pp. 164-175, (2015) (PubMed).
: "GABAergic interneuronal loss and reduced inhibitory synaptic transmission in the hippocampal CA1 region after mild traumatic brain injury." in: Experimental neurology, Vol. 273, pp. 11-23, (2015) (PubMed).
: "Seizure-related regulation of GABAA receptors in spontaneously epileptic rats." in: Neurobiology of disease, Vol. 77, pp. 246-56, (2015) (PubMed).
Synonyms and alternative names related to GABRA1
gamma-aminobutyric acid type A receptor alpha1 subunit (GABRA1), gamma-aminobutyric acid type A receptor alpha1 subunit (Gabra1), gamma-aminobutyric acid (GABA) A receptor, alpha 1 (gabra1), gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 (Gabra1), gamma-aminobutyric acid receptor subunit alpha-1 (LOC100653509), ECA4, EJM, EJM5, Gabra-1, zgc:153566Protein level used designations for GABRA1
- GABA(A) receptor subunit alpha-1
- GABA(A) receptor, alpha 1
- gamma-aminobutyric acid receptor subunit alpha-1
- gamma-aminobutyric acid A receptor, alpha 1
- gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1
- gamma-aminobutyric acid A receptor, alpha 1
- gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
- GABAA alpha 1
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