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gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 Proteins (GABRA6)

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Additionally we are shipping GABRA6 Antibodies (73) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat GABRA6 GABRA6 29708 P30191
GABRA6 2559 Q16445
GABRA6 14399 P16305
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Top GABRA6 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

GABRA6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
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Mouse (Murine) ,
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More Proteins for gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6) Interaction Partners

Human gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6) interaction partners

  1. TMEM132D, COMT (show COMT Proteins) and GABRA6 gene polymorphisms may influence susceptibility to panic disorder(PD) and major depressive disorder(MDD)in Japanese adults; these variants may increase vulnerability to PD by modulating oligodendrocytes and GABA and dopaminergic functions in related brain regions, altering neuronal processing of anxiety-related emotional signals

  2. NOS3 (show NANOS3 Proteins), GABRA6, child abuse, neighborhood crime Gene x Gene, Environment x Environment, and Gene x Environment interactions are associated with different patterns of respiratory sinus arrhythmia reactivity.

  3. The gene-gene interaction at two loci involving GABRA6 and Synapsin II (show SYN2 Proteins) revealed a significant association for development of idiopathic generalized epilepsy.

  4. genetic association study in Chinese Han population: Data suggest an SNP in GABRA6 (rs3219151) is associated with decreased predisposition to schizophrenia via alteration of miroRNA binding to target in 3-prime-untranslated region of GABRA6 mRNA.

  5. GABRA6 mutation, R46W, was identified as a susceptibility gene that may contribute to the pathogenesis of childhood absence epilepsy and cause neuronal disinhibition and increase in seizures via a reduction of alphabetagamma and alphabetadelta receptor function and expression

  6. Part of the interindividual differences observed for anxiety traits measured by the Harm Avoidance dimension could be explained by the GABRA6 gene variability.

  7. significant involvement of alpha (GABRA6) and beta (GABRB2 (show GABRB2 Proteins)) subunits of GABA(A) receptor in epilepsy susceptibility in north Indian population

  8. studies have found prefrontal cortical GABA(A) receptor alpha subunit (show POLG Proteins) alterations in schizophrenia

  9. These findings suggest that common variation in the GABRA2, GABRA3 (show GABRA3 Proteins), GABRA6, and GABRG2 (show GABRG2 Proteins) genes does not play a major role in liability to anxiety spectrum disorders.

  10. These findings support a role for the serotonin transporter (show SLC6A4 Proteins) and GABA(A) alpha6 subunit in depression-related traits.

Mouse (Murine) gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6) interaction partners

  1. D3R modulates GABAA receptors function in striatum: chronic blockade of D3R increases alpha6 subunit expression and induces insensitivity to the anxiolytic effect of diazepam

  2. This study demonstrated that Ectopic Expression of alpha6 GABAA (show GABRg1 Proteins) Receptor Subunits in Hilar Somatostatin (show SST Proteins) Neurons Increases Tonic Inhibition and Alters Network Activity in the Dentate Gyrus.

  3. results indicate that in addition to the central role of homologous gamma-aminobutyric acid (GABA) A receptor subunit alpha 6-100R/Q (alpha1-101H) residue in benzodiazepine(BZ) binding this critical BZ binding site has a major impact on BZ binding kinetics

  4. Differential cell surface expression of GABAA (show GABRg1 Proteins) receptor alpha1, alpha6, beta2 and beta3 subunits in cultured mouse cerebellar granule cells influence of cAMP-activated signalling.

  5. GABRA6 expression is regulated by NFI (show NFIC Proteins) in cerebellar granule neurons

  6. Abnormal cerebellar P/Q-type VGCC activity results in a deficit of CGC-specific subtype(s) of GABA(A) receptors which may contribute to, or may be a consequence of the impaired cerebellar network signaling that occurs in cacna1a(tg (show CACNA1A Proteins)) mice.

  7. some aspects of assembly, trafficking, targeting, and/or expression of extrasynaptic alpha6-containing GABA(A) receptors in cerebellar granule cells are selectively regulated by AMPA (show GRIA3 Proteins) receptor-mediated signaling

  8. We tested the hypothesis that homocysteine (Hcy) antagonizes the GABA(A) receptor and behaves as an excitotoxic neurotransmitter that causes blood brain barrier (BBB) permeability and vascular dementia.

GABRA6 Protein Profile

Protein Summary

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

Gene names and symbols associated with GABRA6

  • gamma-aminobutyric acid (GABA) A receptor, alpha 6 (GABRA6)
  • gamma-aminobutyric acid (GABA) A receptor, alpha 6 (LOC100224835)
  • gamma-aminobutyric acid (GABA) A receptor, alpha 6 (Gabra6)
  • gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6 (Gabra6)
  • alpha6 protein
  • Gabra-6 protein
  • GABRA6 protein
  • LOC100224835 protein

Protein level used designations for GABRA6

gamma-aminobutyric acid receptor subunit alpha-6 , gamma-aminobutyric acid (GABA) A receptor, alpha 6 , gamma-aminobutyric acid A receptor, alpha 6 , gamma-aminobutyric acid receptor subunit alpha-6-like , GABA(A) receptor subunit alpha-6 , GABA-A receptor alpha-6 subunit , gamma-aminobutyric acid A receptor, alpha 6 , gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6 , GABA subunit A receptor alpha 6 , GABA(A) receptor, alpha 6 , GABA-A receptor a6 subunit , GABA-ARalpha6 , gamma-aminobutyric acid A recptor, subunit alpha 6 , subunit alpha 6 gamma-aminobutyric acid (GABA-A) receptor

GENE ID SPECIES
539194 Bos taurus
100224835 Taeniopygia guttata
471725 Pan troglodytes
489145 Canis lupus familiaris
697010 Macaca mulatta
100070890 Equus caballus
100403146 Callithrix jacchus
100444943 Pongo abelii
100480146 Ailuropoda melanoleuca
100585387 Nomascus leucogenys
29708 Rattus norvegicus
2559 Homo sapiens
395931 Gallus gallus
14399 Mus musculus
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