anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) Antibodies

GABRA1 encodes a gamma-aminobutyric acid (GABA) receptor. Additionally we are shipping gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GABRA1 2554 P14867
GABRA1 29705 P62813
GABRA1 14394 P62812
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Top anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 Antibodies at antibodies-online.com

Showing 10 out of 180 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-GABRA1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-GABRA1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated AA, ICC, IF, IHC, WB GABA (A)Ralpha1 h cell line mix. 100 μg Log in to see 2 to 3 Days
$383.90
Details
Human Rabbit Un-conjugated WB Western blot of rat forebrain lysates from Wild Type (Control) and ?1-knockout (?1-K/O) animals showing specific immunolabeling of the ~51k ?1-subunit of the GABAA-R. The labeling was absent from a lysate prepared from ?1-knockout animals. Western Blot: GABA-A R alpha 1 Antibody [ABIN152533] - Analysis of forebraine lysates from wildtype (Lane A) and a1-knockout rats using 5-7 ug of tissue per lane. The antibody labeled the 51 kDa a1-subunit of GABAa-R. The labeling was absent from the lysate prepared from the a1-knockout animals. 0.1 mL Log in to see 7 to 9 Days
$447.56
Details
Mouse Rabbit Un-conjugated WB 0.1 mL Log in to see 7 to 9 Days
$381.94
Details
Rat Mouse Un-conjugated ICC, IHC, WB dilution: 1 : 1000, sample: unboiled synaptic membrane fraction of rat brain (LP1) Indirect immunostaining of hippocampus neurons with anti-GABA-A receptor α1 (dilution 1 : 500; red) and rabbit anti-synapsin 1/2 (cat. no. 106 002, dilution: 1:500; green). 100 μg Log in to see 5 to 6 Days
$444.68
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-GABA A Receptor alpha 1 antibody, IHC(P) IHC(P): Rat Brain Tissue Anti-GABA A Receptor alpha 1 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Rat Brain Tissue Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Brain, antibody was diluted at 1:100. 100 μL Log in to see 16 Days
$175.80
Details
Cow Rabbit Un-conjugated WB   0.1 mL Log in to see 6 to 8 Days
$709.50
Details

GABRA1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 Antibodies

  1. Mammalian Monoclonal GABRA1 Primary Antibody for ISt, IHC - ABIN1304642 : Zhou, Ding, Deel, Ferrick, Emeson, Gallagher: Altered intrathalamic GABAA neurotransmission in a mouse model of a human genetic absence epilepsy syndrome. in Neurobiology of disease 2014 (PubMed)
    Show all 27 Pubmed References

  2. Human Polyclonal GABRA1 Primary Antibody for WB - ABIN152533 : Herden, Pardo, Hajela, Yuan, Atchison: Differential effects of methylmercury on gamma-aminobutyric acid type A receptor currents in rat cerebellar granule and cerebral cortical neurons in culture. in The Journal of pharmacology and experimental therapeutics 2008 (PubMed)
    Show all 11 Pubmed References

  3. Rat (Rattus) Monoclonal GABRA1 Primary Antibody for ICC, IHC - ABIN1742455 : Acuna, Liu, Südhof: How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs. in Neuron 2016 (PubMed)

  4. Mouse (Murine) Polyclonal GABRA1 Primary Antibody for WB - ABIN152548 : Roberts, Hu, Lund, Brooks-Kayal, Russek: Brain-derived neurotrophic factor (BDNF)-induced synthesis of early growth response factor 3 (Egr3) controls the levels of type A GABA receptor alpha 4 subunits in hippocampal neurons. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 Pubmed References

More Antibodies against gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 Interaction Partners

Human gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) interaction partners

  1. The results further substantiate the role of GABRA1 in phenytoin mode of action in epilepsy.

  2. Our study findings showed COMT (show COMT Antibodies) polymorphism conferring risk and GABRA1 and GABRA2 (show GABRA2 Antibodies) polymorphism as a protective genotype for Indian male with alcohol dependence (AD)

  3. The polymorphism of rs1129647 and rs2290733 of GABRA1 has a nominal relationship with amphetamine-induced psychotic disorder .

  4. Study confirms GABRA1 mutations as significant contributors to the genetic etiology of both mild and severe epilepsy syndromes. GABRA1 mutations, through a possible mechanism of haploinsufficiency, cause an impairment of the GABA inhibitory function leading to a wide spectrum of epilepsy phenotypes.

  5. This unique case not only allows to further define the phenotypic spectrum of infantile epileptic encephalopathy associated with rare de novo GABRA1 variants but exemplifies the need for a sensitive review of unclear associations in clinically defined syndromes and for extended diagnostic work-up in individuals with unusual presentations of a genetically confirmed diagnosis.

  6. This study clarifies a Grp94 (show HSP90B1 Antibodies)-mediated ERAD pathway for GABAA (show GABRg1 Antibodies) receptors, which provides a novel way to finely tune their function in physiological and pathophysiological conditions.

  7. GABRA1 missense mutations were linked to early onset epileptic encephalopathies, including Ohtahara syndrome and West syndrome.

  8. Polymorphism rs4263535 in GABRA1 intron 4 was associated with deeper sedation by intravenous midazolam.

  9. Putative GABAA (show GABRg1 Antibodies) and ASIC1a (show ACCN2 Antibodies) channels functionally interact with each other, possibly via an inter-molecular association by forming a novel protein complex.

  10. The role of the N-terminal extension and putative alpha-helix in heteromeric alpha1beta2gamma2 GABAA (show GABRg1 Antibodies) receptors was most prominent in the alpha1 subunit. Deletion reduced the number of functional receptors.

Cow (Bovine) gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) interaction partners

  1. GAPDH (show GAPDH Antibodies) directly phosphorylates the long intracellular loop of GABA(A) receptor alpha1 subunit at identified serine and threonine residues. GAPDH (show GAPDH Antibodies) and the alpha1 subunit were found to be colocalized at the neuronal plasma membrane.

  2. Numerous classes of general anesthetics inhibit etomidate binding to gamma-aminobutyric acid type A (GABAA (show GABRg1 Antibodies)) receptors

Mouse (Murine) gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) interaction partners

  1. This study suggests that movement of loop G in the beta1 strand of the GABAA (show GABRg1 Antibodies) receptor alpha1 subunit is involved in a conformational rearrangement associated with channel activation

  2. These data suggest that GABA, acting through both presynaptic GABAA (show GABRg1 Antibodies) and GABAB receptors, modulate the amplitude and short-term plasticity of excitatory synapses, a result not possible from activation of either receptor type alone

  3. Nbea (show NBEA Antibodies) targets glutamate (show GRIN1 Antibodies) and GABA receptors to the synapse via distinct molecular pathways by interacting with specific effector proteins.

  4. the identity and location of distinct GABAAR (show GABRG2 Antibodies) subunits within the cellular networks of the mouse dorsal raphe nucleus and that stress impacts on the expression levels of particular subunits at the gene and protein level

  5. This study demonstrated that Adolescent-onset GABAA (show GABRg1 Antibodies) alpha1 silencing regulates reward-related decision making in mice.

  6. Enduring loss of tonic but not phasic GABAAR (show GABRG2 Antibodies) currents critically contributes to the prolonged amygdala disinhibition subsequent to chronic stress.

  7. these findings suggest that gephyrin (show GPHN Antibodies) may be a key factor in BDNF (show BDNF Antibodies)-dependent GABAAR (show GABRG2 Antibodies) regulation in the amygdala.

  8. Gabra1 receptors are expressed in the ventral thalamus in an absence epilepsy model.

  9. The effects of heterozygous knock-out of GABAAR (show GABRG2 Antibodies) alpha1 on the expression and physiology of GABAARs in the mouse cortex, were determined.

  10. Cell-type specifici deletion of Gaba(a)alpha1 in corticotropin-releasing factor (show CRH Antibodies)-containing neurons enhances anxiety and disrupts fear extinction.

gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) Antigen Profile

Protein Summary

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.

Gene names and symbols associated with GABRA1

  • gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1) antibody
  • gamma-aminobutyric acid (GABA) A receptor, alpha 1 (Gabra1) antibody
  • gamma-aminobutyric acid (GABA) A receptor, alpha 1 (gabra1) antibody
  • gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 (Gabra1) antibody
  • gamma-aminobutyric acid A receptor subunit alpha-1 (gabra1) antibody
  • ECA4 antibody
  • EJM antibody
  • EJM5 antibody
  • Gabra-1 antibody
  • zgc:153566 antibody

Protein level used designations for GABRA1

GABA(A) receptor subunit alpha-1 , GABA(A) receptor, alpha 1 , gamma-aminobutyric acid receptor subunit alpha-1 , gamma-aminobutyric acid A receptor, alpha 1 , gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1 , gamma-aminobutyric acid A receptor, alpha 1 , gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 , GABAA alpha 1

GENE ID SPECIES
2554 Homo sapiens
29705 Rattus norvegicus
489143 Canis lupus familiaris
780973 Bos taurus
374214 Gallus gallus
768183 Danio rerio
100172731 Pongo abelii
14394 Mus musculus
100653509 Xenopus laevis
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